“The ‘1’ key was not pressed hard enough:” Did a typo kill a cancer paper?

Errors in a 2017 paper about a new cancer test may have occurred because of a simple typo while performing calculations of the tool’s effectiveness.

According to the last author, the “1” key was likely not pressed hard enough.

The error, however small, affected key values “so greatly that the conclusions of the paper can no longer be supported,” the editor said, which prompted the journal to retract the paper. Continue reading “The ‘1’ key was not pressed hard enough:” Did a typo kill a cancer paper?

Child took wrong compound for over a year after “communication error”

Credit: Steven Depolo, Flickr

A journal is retracting a paper after it discovered researchers gave a child the wrong supplement for more than a year.

Rhiannon Bugno, managing editor for Biological Psychiatry, told Retraction Watch the mix-up did not put the patient at risk. However, the mistake was enough for the journal’s editor, John Krystal, of Yale University, to request the retraction of a 2016 paper describing the young girl’s experience taking the compound,“Rett-like Severe Encephalopathy Caused by a De Novo GRIN2B Mutation Is Attenuated by D-serine Dietary Supplement.”

Originally published June 17, 2016, the paper was retracted Jan. 15. Led by corresponding author Xavier Altafaj, of the University of Barcelona (UB) and Bellvitge Biomedical Research Institute (IDIBELL), researchers described using an amino acid, D-serine, to treat a child with a rare genetic disorder that affects neurons.

According to the notice, the researchers did use D-serine in lab work used as proof-of-concept; however, when it came time to try it in the patient, as a result of a “communication error:”

Continue reading Child took wrong compound for over a year after “communication error”

Oops: Elsevier journal retracts the wrong paper

When Saidur Rahman learned last month that his 2010 review paper about nanoparticles in refrigeration systems had been retracted, he was concernedno one at the journal had told him it was going to be pulled.

Rahman, a professor of engineering at Sunway University in Selangor, Malaysia, had recently corrected his 2010 review in Renewable and Sustainable Energy Reviewsspecifically, in January, the journal published a two-page correction rewriting the parts of the paper that were “appear close to some materials we had included in some of our other review research.” But Rahman was not anticipating a retraction. Continue reading Oops: Elsevier journal retracts the wrong paper

Caught Our Notice: No retraction for “likely fraudulent” study

Title: Homocysteine as a predictive factor for hip fracture in elderly women with Parkinson’s disease

What Caught Our Attention:  In a letter to the editor, researchers led by Mark Bolland recently outlined the many reasons why a study by Yoshihiro Sato and colleagues in The American Journal of Medicine was “unreliable,” including evidence that the patient numbers were not achievable as described, and inconsistencies and errors in the study data. And let’s not forget a 2016 analysis (co-authored by Bolland) which cast doubt on Sato’s body of work, suggesting that more than 30 of his papers could be problematic. Continue reading Caught Our Notice: No retraction for “likely fraudulent” study

A “GROSS CASE OF PLAGIARISM:” How did one Elsevier journal plagiarize another?

Nicholas Peppas

When Nicholas Peppas, chair of engineering at the University of Texas at Austin, discovered one of his papers had been plagiarized, he decided to “go public!”

On February 27, Peppas tweeted about a “gross case of plagiarism:” He alleged a 2013 review published in Saudi Pharmaceutical Journal had directly copied sections of his 2011 review in Advanced Drug Delivery Reviews—both published by Elsevier. (The tweet includes a side-by-side image of a section of the two texts.) Continue reading A “GROSS CASE OF PLAGIARISM:” How did one Elsevier journal plagiarize another?

New tool looks for signs of image doctoring

Mary Walsh

One of the most common reasons for retractions is image manipulation. When searching for evidence of it, researchers often rely on what their eyes tell them. But what if screening tools could help? Last week, researchers described a new automated tool to screen images for duplication (reported by Nature News); with help from publishing giant Elsevier, another group at Harvard Medical School is developing a different approach. We spoke with creators Mary Walsh, Chief Scientific Investigator in the Office for Professional Standards and Integrity, and Daniel Wainstock, Associate Director of Research Integrity, about how the tool works, and why — unlike the other recently described automated tool — they want to make theirs freely available.

Retraction Watch: What prompted you to develop this tool?

Continue reading New tool looks for signs of image doctoring

Overlooked virus “generated a mess,” infected highly cited Cell, PNAS papers

When Alexander Harms arrived at the University of Copenhagen in August 2016, as a postdoc planning to study a type of antibiotic resistance in bacteria, he carried with him a warning from another lab who had recruited him:

People said, “If you go there, you have to deal with these weird articles that nobody believes.”

The papers in question had been published in the Proceedings of the National Academy of Sciences in 2011 and Cell in 2013. Led by Kenn Gerdes, Harms’s new lab director, the work laid out a complex chain of events that mapped out how an E. coli bacterium can go into a dormant state, called persistence, that allows it to survive while the rest of its colony is wiped out.

Despite some experts’ skepticism, each paper had been cited hundreds of times. And Harms told us:

I personally did believe in the published work. There had been papers from others that kind of attacked [the Gerdes lab’s theory], but that was not high-quality work.

But by November 2016, Harms figured out that the skeptics had been right.  Continue reading Overlooked virus “generated a mess,” infected highly cited Cell, PNAS papers

After “considerable intellectual agony,” journal retracts Wansink paper

Eduardo Franco

Ever since critics began raising concerns about high-profile food scientist Brian Wansink’s work, he’s had to issue a series of high-profile retractions — and now has his seventh (including one paper that was retracted twice, after the journal removed a revised version, along with 14 corrections). The latest notice — first reported by BuzzFeed —  is for a paper that was originally corrected by the journal Preventive Medicine earlier this month — and the correction notice was longer (1636 words) than the original, highly cited paper (1401 words). Following criticism by James Heathers about the highly cited study back in March 2017, the authors issued a series of changes, including explaining the children studied were preschoolers (3-5 years old), not preteens (8-11), as originally claimed. (They made that mistake once before, in another retracted paper.) But critics remained concerned. Yesterday, the journal retracted the paper. We spoke with editor Eduardo Franco of McGill University — who provided us with an advanced copy of an accompanying editorial, soon to be published — about the editorial processes behind the two notices, including the moment the journal knew the correction wouldn’t suffice.

Retraction Watch: You write that the initial decision to correct the paper came with “considerable intellectual agony.” Can you say why?

Continue reading After “considerable intellectual agony,” journal retracts Wansink paper

Caught Our Notice: Brian Wansink issues correction that’s longer than original paper

Title: Attractive names sustain increased vegetable intake in schools

What Caught Our Attention: One thing can be said for the corrections for Brian Wansink‘s papers — they aren’t short.  After James Heathers outlined some of his concerns about the highly cited study back in March, 2017, the journal has issued a correction, and it’s longer (1636 words) than the original, highly cited paper (1401 words). Some of the changes include explaining the children studied were preschoolers (3-5 years old), not preteens (8-11), as originally claimed. (It may be hard to imagine how the authors could make such a mistake, but they did it once before, in another retracted paper.) Even with all those words explaining the correction — we’re only including an excerpt of the entire notice below — some concerns still remain: Continue reading Caught Our Notice: Brian Wansink issues correction that’s longer than original paper

Study that said hate cuts 12 years off gay lives fails to replicate

A highly cited paper has received a major correction as a result of the ongoing battle over attitudes towards gay people, when a prominent — and polarizing — critic showed it could not be replicated.  

In December 2017, researchers led by Mark Hatzenbuehler of Columbia University corrected the paper, originally published in Social Science & Medicine in February 2014, which showed that gay people who live in areas where people were highly prejudiced against them had a significantly shorter life expectancy. The corrigendum came more than a year after a researcher who has testified against same-sex marriage was unable to replicate the original study.

“Structural stigma and all-cause mortality in sexual minority populations,” has been cited 102 times, according to Clarivate Analytics’ Web of Science, and attracted media coverage when it was published, from outlets such as Reuters and U.S. News & World Report.

Continue reading Study that said hate cuts 12 years off gay lives fails to replicate