Category: cancer (journal)

“The sampling had been compromised:” MD Anderson researchers retract cancer study

Erich Sturgis

Researchers from the University of Texas, MD Anderson Cancer Center have retracted a 2015 paper after they discovered their samples had been compromised.

Exactly how the samples were compromised, and how and when the researchers found out, remains unclear.

Originally published March 30, 2015, in Cancer, “Genome-wide association study identifies common genetic variants associated with salivary gland carcinoma and its subtypes” reported that at least three protein-coding gene variants were associated with rare salivary gland cancers. In the paper, the authors — all but one of whom are affiliated with MD Anderson — cautioned that they still needed to confirm the findings and figure out the mechanism by which the genes might increase the risk of cancer.

On Oct. 23, 2017, the researchers asked the journal to either correct or withdraw the paper. According to the retraction notice issued Jan. 9, the researchers had discovered: Continue reading “The sampling had been compromised:” MD Anderson researchers retract cancer study

A researcher sued critics of his work. Now he has 13 retractions.

Fazlul Sarkar
Fazlul Sarkar

A cancer researcher who sued PubPeer commenters for criticizing his work has lost six more papers, bringing his total to 13 retractions. 

Four of the new retraction notices issued by the journal Cancer cite an investigation at Wayne State University in Michigan into the work of Fazlul Sarkar and some of his colleagues. All the new notices, including the other two in Breast Cancer Research and Treatment, are for image-related issues.

Retraction Watch readers will recognize the name Fazlul Sarkar, who took PubPeer to court to unmask the anonymous critics whose comments cost him a job at the University of Mississippi. According to this document, Sarkar retired from Wayne State this year.  

Here’s the first of the four Cancer retraction notices, all of which were issued on July 29: Continue reading A researcher sued critics of his work. Now he has 13 retractions.

Study by deceased award-winning cancer researcher retracted because some patients were “invented”

cancerA 2002 paper has been retracted by Cancer after some of the authors notified the journal that they hadn’t agreed to submit it — and an investigation found that a number of the patients described had been made up.

Here’s the notice for “Radioimmunotherapy of small-volume disease of metastatic colorectal cancer: results of a phase II trial with the iodine-131–labeled humanized anti–carcinoembryonic antigen antibody hMN-14:” Continue reading Study by deceased award-winning cancer researcher retracted because some patients were “invented”

ORI, OHRP find “some human subject issues” in Henschke lung cancer studies, but no evidence of misconduct

cancerWe have an update on two papers about lung cancer screening by Claudia Henschke and colleagues that were subject to an Expression of Concern early last year.

The original Expression of Concern in Cancer read, in part: Continue reading ORI, OHRP find “some human subject issues” in Henschke lung cancer studies, but no evidence of misconduct

Cancer issues expression of concern about two Henschke I-ELCAP lung cancer screening papers

The journal Cancer has issued an Expression of Concern about two lung cancer screening papers long dogged by doubt.

Last April, The Cancer Letter and The New York Times jointly published an investigation into the International Early Lung Cancer Action Program (I-ELCAP) run by Claudia Henschke and David Yankelevitz. Other researchers had already criticized the design and conclusions of that trial, but as the investigation noted, an October 2008 review of the study found that the researchers couldn’t find 90 percent of the subjects’ consent forms, an ethical no-no that jeopardizes as many as 135 papers.

Two papers published in Cancer, in 2000 and 2001, are among those studies, according to the notice (links added), which credits the Times and The Cancer Letter and notes that the journal has referred the case to Federal investigators: Continue reading Cancer issues expression of concern about two Henschke I-ELCAP lung cancer screening papers