Major fraud probe of Japanese anesthesiologist Yoshitaka Fujii may challenge retraction record

We have learned that a widely published Japanese anesthesiologist is under investigation by his university over concerns that he engaged in repeated fraud for decades that has tainted roughly 180 articles—many of which may be retracted as a result.

In a related move, the journal Clinical Therapeutics is retracting papers by the researcher, Yoshitaka Fujii, most recently of Toho University, in Tokyo. Judy Pachella, managing editor of the journal, confirmed the retractions but would not state how many papers were affected. Clinical Therapeutics published 17 articles by Fujii, between 2003 and 2010.

Continue reading Major fraud probe of Japanese anesthesiologist Yoshitaka Fujii may challenge retraction record

Tsuji explains why JBC paper was retracted: Western blot problems

Last week, we reported on the retraction of a paper in the Journal of Biological Chemistry (JBC) that had one of the journal’s typically inscrutable retraction notices.:

This article has been withdrawn by the authors.

Late last week, we heard back from corresponding author Takashi Tsuji by email. It turns out one of our commenters had basically figured out what was wrong. It was, as seems to often be the case lately in retractions we cover, troubles with Western blots: Continue reading Tsuji explains why JBC paper was retracted: Western blot problems

Mysterious retraction in the Journal of Biological Chemistry for Takashi Tsuji’s group

The authors of a paper in the Journal of Biological Chemistry (JBC) have retracted it, but don’t ask us why.

This being the JBC, the retraction notice for “Human T-cell Leukemia Virus Type I Tax Down-regulates the Expression of Phosphatidylinositol 3,4,5-Trisphosphate Inositol Phosphatases via the NF-κB Pathway” is the very definition of opaque: Continue reading Mysterious retraction in the Journal of Biological Chemistry for Takashi Tsuji’s group

A retraction as a group’s papers on smoking and weight loss are too close for comfort

The American Journal of Physiology Endocrinology and Metabolism is retracting a 2009 article by Japanese researchers who appeared to be so fond of their data they published them thrice.

The paper, “Dual suppression of adipogenesis by cigarette smoke through activation of the aryl hydrocarbon receptor and induction of endoplasmic reticulum stress,” by Masanori Kitamura and colleagues, looked at the biochemical mechanism by which cigarette smokers seem to be able to keep weight off. It has been cited eight times, according to Thomson Scientific’s Web of Knowledge.

But according to the retraction notice: Continue reading A retraction as a group’s papers on smoking and weight loss are too close for comfort

That’s a Mori! Seven more retractions brings latest count to 30

The other day we reported that Naoki Mori had lost his 23rd paper to retraction for image manipulation and duplication. Turns out we were wrong by a pretty wide margin.

The International Journal of Cancer has retracted seven more articles by the disgraced Japanese researcher, all for the same reasons:

The following article has been retracted through agreement between the first author and several coauthors, the journal Editor in-Chief, Peter Lichter, and John Wiley & Sons, Ltd. … After an investigation the retraction has been agreed due to inappropriate duplication of images and overlap with other published work.

The papers are as follows: Continue reading That’s a Mori! Seven more retractions brings latest count to 30

Another retraction for Naoki Mori (make that 23?)

The retraction total for Naoki Mori continues to rise.

The October issue of Biochemical and Biophysical Research Communications has retracted a 2007 paper by Mori et al for the same issues — manipulated images — that  brought down the 20-odd other papers of his since the scandal broke in late December.

Here’s the notice for the pulled paper, titled “Downregulation of citrin, a mitochondrial AGC, is associated with apoptosis of hepatocytes:” Continue reading Another retraction for Naoki Mori (make that 23?)

Lack of ethical approval leads to JCO retraction

The Retraction Watch category for “lack of IRB approval” as a reason for retraction — a subject we covered in our most recent Lab Times column — is growing. First there were the 90-odd retractions by Joachim Boldt, then three by Australian researchers studying Aussie-rules football players. Now, we learn that the Journal of Clinical Oncology has retracted a paper over concerns that the authors failed to obtain ethical approval to conduct their study.

The 2010 publication, by researchers at Saitama Medical University in Japan, reported on an analysis of 314 lymphoma patients being treated with chemotherapy — some, and perhaps none, of whom knew they were being studied.

Here’s the notice, which appeared this month: Continue reading Lack of ethical approval leads to JCO retraction

More on Hattori case from co-author: Did grudge lead to scientist’s fall?

We have an update on the case of Yoshiyuki Hattori, the Japanese endocrinologist who has had a half-dozen papers retracted because of issues involving reused data. We’ve reported on some of those retractions, and report on three new ones here.

As a trainee, Hattori spent some time in England, where he met Steven Gross, a prominent pharmacology researcher at Cornell. Gross was impressed with the young physician-scientist, and invited him back to his New York City laboratory to do a postdoc.

Gross’ name appears on one of the retracted articles, “NO suppresses while peroxynitrite sustains NF-κB: a paradigm to rationalize cytoprotective and cytotoxic actions attributed to NO,” which appeared in 2004 in the journal Cardiovascular Research and has been cited 42 times, according to Thomson Scientific’s Web of Knowledge.

According to the notice: Continue reading More on Hattori case from co-author: Did grudge lead to scientist’s fall?

The ‘Goldilocks’ retraction? Revealing differences in how several neurology journals handled related problems

Four neurology journals have retracted articles by a Japanese researcher who admitted to having made “mistakes” in his handling of data. Although the cases are related, the way the journals have handled the  notices is startlingly different. One chose to say nothing, one chose to say little, while two went for full — or at least, approximately that — disclosure.

Guess which ones we like the most? Continue reading The ‘Goldilocks’ retraction? Revealing differences in how several neurology journals handled related problems

Group under investigation retracts second paper, claims errant figure was just a placeholder

The authors of a 2010 Journal of Immunology paper have retracted it, saying that part of one of the figures was actually a placeholder from another experiment.

According to the retraction notice for “Stimulation of FcgRI on Primary Sensory Neurons Increases Insulin-Like Growth Factor-I Production, Thereby Reducing Reperfusion-Induced Renal Injury in Mice” by Naoaki Harada, Juan Zhao, Hiroki Kurihara, Naomi Nakagata, and Kenji Okajima: Continue reading Group under investigation retracts second paper, claims errant figure was just a placeholder