Retraction Watch

Tracking retractions as a window into the scientific process

Archive for the ‘jbc retractions’ Category

Prominent Harvard researcher issues second retraction, again citing duplication

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The former president of the Joslin Diabetes Center has withdrawn a second article within a month of his first, and issued extensive corrections to another paper in the same journal, all due to figure errors.

In November, we reported that Carl Ronald Kahn — also affiliated with Harvard Medical School — had pulled a highly cited 2005 paper from The Journal of Clinical Investigation because of image duplication issues, which Kahn told us were introduced during figure assembly. This December, Kahn retracted a 2003 paper published in The Journal of Biological Chemistry (JBC)—again due to duplication issues that the authors believe “were inadvertently introduced during figure assembly.”

Here’s the retraction notice for “Bi-directional regulation of brown fat adipogenesis by the insulin receptor,” cited 46 times, according to Clarivate Analytics’ Web of Science, formerly part of Thomson Reuters:

Read the rest of this entry »

“An example for all authors to uphold:” Researcher logs 5 corrections

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A scientist in Ireland has corrected five of his papers in a single journal dating back more than a decade, after image-related problems were brought to his attention.

Four of the newly corrected papers have a common last and corresponding author: Luke O’Neill of Trinity College Dublin in the Republic of Ireland. O’Neill is also a co-author of the remaining paper that was fixed. O’Neill told us the mistakes were a “bit sloppy,” noting that he takes responsibility for the errors in the four papers on which he is last author.

O’Neill forwarded Retraction Watch a comment he received from Kaoru Sakabe — data integrity manager at the American Society for Biochemistry and Molecular Biology (which publishes The Journal of Biological Chemistry (JBC)) — that reads: Read the rest of this entry »

Authors in Spain issue string of corrections

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Following a journal probe and questions on PubPeer about their work, authors in Spain have issued four corrections, citing missing raw data for experiments conducted more than 10 years ago.

All papers include the same last two authors, Mireia Duñach at the Autonomous University of Barcelona, and Antonio García de Herreros at the Institut Hospital del Mar d’Investigacions Mèdiques.

Three of the corrections were issued by the Journal of Biological Chemistry, from which the authors retracted three papers earlier this year after a journal investigation concluded they contain reused images, designed to represent different experiments.

Duñach told us the latest corrections are the result of her own initiation:

Read the rest of this entry »

Written by Alison McCook

December 30th, 2016 at 9:30 am

Researcher logs three retractions for image duplications — two of which with familiar co-authors

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A researcher in Brazil is taking responsibility for accidentally mixing up images in three papers in the Journal of Biological Chemistry. 

The corresponding author on the three papers told us the mistake happened because the studies were conducted simultaneously, and relied on one computer.

There’s a side note to these retractions: The co-author list on two papers includes names that should be fairly well-known to our readers — Mario Saad, the researcher who unsuccessfully sued the American Diabetes Association to stop retractions of his papers, and Rui Curi, a researcher whose legal threats assisted in the shutdown of This makes Saad’s ninth retraction.

According to the retraction notices, Lício Velloso  — who, like his co-authors, is based at the University of Campinas in São Paulo, Brazil — assembled all the figures. He told Retraction Watch that the authors initially wanted to correct the papers, adding: Read the rest of this entry »

How a researcher’s request to correct one paper turned into 19 retractions

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Jin Cheng

Last year, a cancer researcher wrote to the Journal of Biological Chemistry, asking to correct one of his papers. The journal responded by requesting the raw data used to prepare his figures. Then, in a follow-up request, it asked for raw data behind the figures in 20 additional published articles.

And when all was said and done six months later, Jin Cheng ended up with far more than just a single correction: Last month, the journal issued withdrawals for 19 of his papers — including the paper he originally asked to correct — along with one correction.

We’ve pieced together some clues about what happened after reviewing correspondence between representatives of JBC and Moffitt Cancer Center, where Cheng conducted his research. A spokesperson for Moffitt confirmed that the retractions did not initiate from an institutional investigation — but that the institution is now conducting one.

That’s not the way retractions typically happen: Often, journals don’t have the resources to conduct investigations themselves, so institutions mostly take the lead in double-checking papers and, if necessary, contacting the journal to initiate a retraction. Here, it seems the opposite took place.

The Moffitt spokesperson also told us that Read the rest of this entry »

Cancer researcher retracts 19 studies at once

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Jin Cheng

A former cancer biologist at the Moffitt Cancer Center in Tampa, Florida has retracted 19 papers from a single journal.

Jin Cheng, who studies how ovarian cancer develops, withdrew 19 papers from the Journal of Biological Chemistry originally published over the last 15 years, and corrected another. All of the retractions are for image manipulation.

For example, here’s the notice for “Activation of phosphatidylinositol 3-kinase/Akt pathway by androgen through interaction of p85α, androgen receptor, and Src,” a paper originally published in 2003: Read the rest of this entry »

Written by Ivan Oransky

October 21st, 2016 at 11:38 am

Researcher pegged for misconduct in 11 papers earns 2nd retraction

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clinical-cancer-researchA cancer journal has retracted a paper by a researcher who doctored data in 11 studies, according to a report by the U.S. Office of Research Integrity (ORI).

According to an investigation report released by the ORI last year, all 11 studies co-authored by Girija Dasmahapatra, formerly based at Virginia Commonwealth University (VCU) in Richmond, will either be retracted or corrected. In April, Dasmahapatra lost the first of the 11 papers flagged by the ORI in the journal Leukemia. Earlier this month, a second paper from the list was pulled by Clinical Cancer Research.

Dasmahapatra isn’t the only VCU researcher who’s been busy correcting the literature. All 11 papers mentioned in the ORI report list Steven Grant as last author; Paul Dent is a co-author of nine of these studies. Last month, we reported on a retraction in the Journal of Biological Chemistry (JBC) and a mega-correction in Molecular Pharmacology issued for papers by Grant and Dent due to problems with images. Neither paper included Dasmahapatra as a co-author.

We’ve also previously reported on four other errata for image-related issues for papers by Dent (one of which lists Grant as a co-author). Now, we’ve come across another correction in JBC for the pair, which was published last month.

First, here’s the new retraction notice from Clinical Cancer Research, which includes Grant and Dent as co-authors: Read the rest of this entry »

Cancer biologist says Nature journal “censored” his News & Views, retracts it

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nature-reviews-clinical-oncologyA cancer biologist has retracted a 2016 News & Views article in a Nature journal, alleging that the journal tried to censor his writing by asking him to remove passages that criticized another journal (Cell)

Carlo Croce, the sole author of the article in Nature Reviews Clinical Oncology from Ohio State University in Columbus, described the journal’s actions to us as “disgusting” and “worrisome.”

A spokesperson from the journal sent us this statement:

We regret that this situation occurred. We cannot comment beyond the retraction notice.

This isn’t Croce’s first retraction (we just found another recent one, in the Journal of Biological Chemistry, over image problems). He’s also co-authored multiple papers with Alfredo Fusco, a cancer researcher in Italy who has nine retractions under his belt, and is undergoing criminal investigation for scientific misconduct.

Here’s the retraction notice, published in Nature Reviews Clinical Oncology on October 4: Read the rest of this entry »

Author asks to retract nearly 20-year old paper over figure questions, lack of data

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journal-of-biological-chemistryThe last author of a 1999 paper has asked the journal to retract it less than one month after a user raised questions about images on PubPeer.

Yesterday, last author Jim Woodgett posted a note on the site saying the author who generated the figures in question could not find the original data, and since he agreed the images appeared “suspicious,” he had contacted the journal to retract the paper.

Here’s the note from Woodgett, based at Lunenfeld-Tanenbaum
Research Institute at Mount Sinai Hospital in Toronto: Read the rest of this entry »

Researcher in Ireland loses two 13-year old studies

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journal-of-biological-chemistryThe Journal of Biological Chemistry (JBC) has retracted two 2003 studies after concluding that figures in the papers had been duplicated, and portions of some figures in one paper “did not accurately represent the results of the experimental conditions.”

The two newly retracted papers have the same last author — Therese Kinsella, a biochemist at the University College Dublin (UCD), who told us the data have been upheld by subsequent research, but that she supports the retractions, which are now part of a UCD investigation.

The retractions will bring up some familiar names: The first author on one of the papers is Sinéad Miggin from Maynooth University in the Republic of Ireland; in 2014, Miggin logged two retractions in the JBC, which triggered an investigation into co-author Aisha Qasim ButtLast year, Maynooth University revoked Butt’s PhD after she admitted to “falsification and misrepresentation” of data in both studies as well as her PhD thesis. At the time, Miggin and two other researchers were fully exonerated by Maynooth University from “any wrongdoing.”

Butt, however, is not an author of either of the newly retracted papers. Although Butt’s LinkedIn page still lists her as a postdoctoral researcher at UCD, a spokesperson from the institution told us she is no longer based there.

We don’t often see such old papers retracted. Kaoru Sakabe, Manager of Publishing Issues at the American Society for Biochemistry and Molecular Biology, which publishes JBC, told us how this decision came about: Read the rest of this entry »