Retraction Watch

Tracking retractions as a window into the scientific process

Archive for the ‘cancer (journal)’ Category

Study by deceased award-winning cancer researcher retracted because some patients were “invented”

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cancerA 2002 paper has been retracted by Cancer after some of the authors notified the journal that they hadn’t agreed to submit it — and an investigation found that a number of the patients described had been made up.

Here’s the notice for “Radioimmunotherapy of small-volume disease of metastatic colorectal cancer: results of a phase II trial with the iodine-131–labeled humanized anti–carcinoembryonic antigen antibody hMN-14:” Read the rest of this entry »

Written by Ivan Oransky

April 9th, 2015 at 11:30 am

ORI, OHRP find “some human subject issues” in Henschke lung cancer studies, but no evidence of misconduct

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cancerWe have an update on two papers about lung cancer screening by Claudia Henschke and colleagues that were subject to an Expression of Concern early last year.

The original Expression of Concern in Cancer read, in part: Read the rest of this entry »

Cancer issues expression of concern about two Henschke I-ELCAP lung cancer screening papers

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The journal Cancer has issued an Expression of Concern about two lung cancer screening papers long dogged by doubt.

Last April, The Cancer Letter and The New York Times jointly published an investigation into the International Early Lung Cancer Action Program (I-ELCAP) run by Claudia Henschke and David Yankelevitz. Other researchers had already criticized the design and conclusions of that trial, but as the investigation noted, an October 2008 review of the study found that the researchers couldn’t find 90 percent of the subjects’ consent forms, an ethical no-no that jeopardizes as many as 135 papers.

Two papers published in Cancer, in 2000 and 2001, are among those studies, according to the notice (links added), which credits the Times and The Cancer Letter and notes that the journal has referred the case to Federal investigators: Read the rest of this entry »