Retraction Watch

Tracking retractions as a window into the scientific process

Archive for the ‘karolinska institutet’ Category

Huh? Cancer paper gets retracted because of its correction

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Here’s a rather odd case: When readers raised issues about some of the images in a 2008 cancer paper, the authors issued a correction last year. But when readers asked additional questions about the corrected images, the authors decided to retract the paper entirely, along with its correction.

Both the original and corrected versions were questioned on PubPeer.

Here’s the retraction notice for the 2008 article “PRIMA-1MET induces mitochondrial apoptosis through activation of caspase-2,” published in Oncogene, which includes a link to the July 2016 correction: Read the rest of this entry »

Karolinska requests retraction of 2014 Macchiarini paper

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Paolo Macchiarini

It has been a tough couple of years for surgeon Paolo Macchiarini, once lauded for pioneering a groundbreaking procedure to transplant tracheas.

After a series of documentaries prompted his former employer, Karolinska Institutet (KI), to reopen a misconduct investigation against him, KI has today released one verdict regarding a 2014 Nature Communications paper: guilty.

KI said it is contacting the journal to request a retraction of the paper, which has already been flagged with an expression of concern.

Here’s more from a release from the institution: Read the rest of this entry »

Macchiarini dismissed from Karolinska

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Paolo Macchiarini

Paolo Macchiarini

The Karolinska Institutet has dismissed former rising star surgeon Paolo Macchiarini from his post, effective immediately.

A KI news release, dated today, states:

The Staff Disciplinary Board at Karolinska Institutet has today decided to relieve Paolo Macchiarini of his duties as a researcher at KI. He is to be informed immediately that his contract has been rescinded.

For a refresher on the story, check out our constantly updating timeline. As a brief recap: Read the rest of this entry »

Written by Alison McCook

March 23rd, 2016 at 7:35 am

Whistleblower removed from Macchiarini’s Lancet author list

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Paolo Macchiarini

Paolo Macchiarini

Last week, The Lancet honored a co-author’s request to remove his name from Paolo Macchiarini’s seminal 2011 paper, which described the first transplant of an artificial trachea seeded with autologous stem cells but has since come under fire.

On March 3, the journal posted this notice:

The Lancet has been contacted by Dr KH Grinnemo who was an author on the paper. Dr Grinnemo no longer wishes to be an author and asks for his name to be removed. This correction has been made to the online version as of March 3, 2016.

The paper has been cited 187 times, designating it “highly cited” by Thomson Reuters Web of Science.

As The Scientist reports, Karl-Henrik Grinnemo is one of the four surgeons at Karolinska Hospital who filed a complaint against Macchiarini in 2014 — alleging, for instance, Read the rest of this entry »

Written by Alison McCook

March 8th, 2016 at 11:30 am

Macchiarini may be dismissed from Karolinska; dean of research resigns

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Paolo Macchiarini

Paolo Macchiarini

There’s more news to report on the story of surgeon Paolo Macchiarini, who’s been dogged by allegations of misconduct.

After the Karolinska Institutet (KI) announced it would not extend his contract and that he needed to “phase out” his research by November, it has now announced it may dismiss him.

In addition, Hans-Gustaf Ljunggren, KI’s Dean of Research, has resigned.

Here’s the statement we received from a KI spokesperson:

Read the rest of this entry »

Written by Alison McCook

February 22nd, 2016 at 4:41 pm

Karolinska vice-chancellor resigns following criticism of Macchiarini investigation

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Anders Hamsten

Anders Hamsten

Anders Hamsten announced he would be resigning as vice-chancellor from Karolinska Institutet (KI) in the early hours of Saturday, February 13.

In a press release we received at 12:16 a.m. local time in Stockholm, Hamsten issued the following statement:

Following the criticism on the so called Macchiarini affair at KI I conclude it will be hard for me to serve as Vice-Chancellor with the strength and credibility this university needs. I will therefore leave office.

Good thing we published a primer on the whole story a few hours ago. To recap: Read the rest of this entry »

Written by Alison McCook

February 12th, 2016 at 7:00 pm

Karolinska orders new investigation of trachea surgeon Macchiarini

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Paolo Macchiarini

Paolo Macchiarini

The Karolinska Institutet University Board announced today it was issuing a new external investigation of trachea surgeon Paolo Macchiarini, looking into questions about his recruitment and the handling of previous allegations of misconduct.

According to a press release:

The University Board deems such an inquiry to be an important part of restoring the confidence of the public, the scientific community, staff and students in the university.

The board hopes to appoint the investigative team, which will not consider “matters of a medical-scientific nature,” next week. The goal is to conclude the investigation by the summer.

There were many signs this was coming:  Read the rest of this entry »

Written by Alison McCook

February 5th, 2016 at 8:30 am

Karolinska won’t extend star surgeon Macchiarini’s contract

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dr-paolo-macchiarini

Paolo Macchiarini

Karolinska Institutet announced today it would not extend the contract of star surgeon Paolo Macchiarini. He has been instructed to “phase out” his research from now until November 30.

According to a press release issued today: Read the rest of this entry »

Written by Alison McCook

February 4th, 2016 at 11:35 am

Trachea surgeon Macchiarini acted “without due care,” but is not guilty of misconduct: Karolinska

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Paolo Macchiarini

Paolo Macchiarini

Following an investigation, Karolinska Institutet has found that surgeon and visiting professor Paolo Macchiarini acted in some cases “without due care,” but that his behavior “does not qualify as scientific misconduct.”

Karolinska’s Vice Chancellor has also recommended that Macchiarini submit an unspecified number of corrections “to clarify and rectify the failings that the inquiry has brought to light.”

Macchiarini is most well-known for pioneering the creation of tracheas from cadavers and patients’ own stem cells. However, the glow of his success was diminished somewhat after four Karolinska surgeons filed a complaint, alleging Macchiarini had downplayed the risks of the procedure and not obtained proper consent, among other accusations.

An external review by Bengt Gerdin of Uppsala University concluded in May that Read the rest of this entry »

Written by Alison McCook

August 28th, 2015 at 8:45 am

Journal of Neuroscience retracts plasticity paper for “substantial data misrepresentation”

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jneuroscicoverThe Journal of Neuroscience has retracted a 2012 paper by a group from Sweden’s Karolinska Institutet for what appears to be research misconduct. But more on that in a moment.

The article, “The Existence of FGFR1-5-HT1A Receptor Heterocomplexes in Midbrain 5-HT Neurons of the Rat: Relevance for Neuroplasticity,” came from the lab of Kjell Fuxe, whose interests include Parkinson’s disease, addiction and depression. The first and second authors, Dasiel Oscar Borroto-Escuela and Wilber Romero-Fernandez, are listed as being post-docs in the lab.

According to the notice: Read the rest of this entry »