Category: zhiguo wang

Corrections in PLoS One, Nature Medicine for Zhiguo Wang, and details about Montreal Heart Institute investigation

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PLoS One and Nature Medicine have issued corrections for papers by Zhiguo Wang, the former Montreal Heart Institute researcher who resigned in September following an investigation into image manipulation in his lab. 

In September, PLoS One told us that they were investigating the paper. Here’s the text of the correction for “Transcriptional and Post-Transcriptional Mechanisms for Oncogenic Overexpression of Ether À Go-Go K+ Channel:” Continue reading Corrections in PLoS One, Nature Medicine for Zhiguo Wang, and details about Montreal Heart Institute investigation

Zhiguo Wang retractions appear in the Journal of Cellular Physiology

Last month, we reported that the last three of six promised retractions by Zhiguo Wang, who was a researcher at the Montreal Heart Institute until the results of an Institute investigation forced him to resign in early September — would be in the Journal of Cellular Physiology. They’ve now appeared.

Here are the three notices, which are far more informative than the Journal of Biological Chemistry was — and which make it clear Wang acted alone: Continue reading Zhiguo Wang retractions appear in the Journal of Cellular Physiology

Remaining Zhiguo Wang retractions will be in the Journal of Cellular Physiology

We’ve been following the case of Zhiguo Wang, the former Montreal Heart Institute researcher who was forced to resign his post in early September following an investigation into his work. At the time of that announcement, two retractions of the Wang group’s papers — which we had reported on in August — had appeared. The Institute said they had requested three more.

We figured that meant a total of five, although the Institute wouldn’t say which they were. So when we found out about a third retraction, in the Journal of Cell Science, we said it was the first of the remaining three.

We were wrong. Continue reading Remaining Zhiguo Wang retractions will be in the Journal of Cellular Physiology

Nature Medicine paper by former Montreal Heart Institute researcher Zhiguo Wang unlikely to be retracted

We’ve been reporting on the case of Zhiguo Wang, the Montreal Heart Institute researcher who was dismissed earlier this month for scientific misconduct. In the announcement about Wang’s dismissal, the institute said it had requested the retraction of three papers other than the two that Wang had himself retracted earlier this summer, making a total of five.

We’ve been following up with journals that published Wang’s work, with the help of eagle-eyed Retraction Watch readers, and last week reported on the first of those three additional retractions, in the Journal of Cell Science. Late last week, we heard from Juan Carlos Lopez, the chief editor of Nature Medicine, which had published a paper by the group. Lopez had earlier said he was waiting for a Montreal Heart Institute report on their findings. He tells us it’s unlikely the Nature Medicine paper will be among those retracted: Continue reading Nature Medicine paper by former Montreal Heart Institute researcher Zhiguo Wang unlikely to be retracted

Third retraction from dismissed Montreal cardiology researcher Zhiguo Wang appears

Ten days ago, we reported on the dismissal of Zhiguo Wang, a Montreal Heart Institute researcher who had already retracted two papers because of image manipulation. At the time, an official said the institute had requested three more retractions, but when we asked which three papers, we were told:

As written in the press release, the MHI has requested the retraction of three additional scientific articles. We will not be able to confirm the name of the scientific articles and/or publications until confirmation of the retractions.

The first of those three has now appeared, in the Journal of Cell Science, for the 2007 paper, “The muscle-specific microRNAs miR-1 and miR-133 produce opposing effects on apoptosis by targeting HSP60, HSP70 and caspase-9 in cardiomyocytes.” According to the retraction notice — which is unfortunately behind a paywall (see update at end): Continue reading Third retraction from dismissed Montreal cardiology researcher Zhiguo Wang appears

Montreal Heart Institute researcher dismissed following two retractions for image manipulation

A Montreal Heart Institute researcher who retracted two papers less than a month ago has been fired from his post.

Zhiguo Wang, who had been funded by the Canadian Institute of Health Research and the Canadian Diabetes Association, studied the genes linked to heart rhythm abnormalities, among other subjects. Wang also has an appointment at the University of Montreal.

As first reported in Retraction Watch, Wang withdrew two papers for the Journal of Biological Chemistry (JBC) in the journal’s August 12 issue. The story was quickly picked up by Postmedia and the CBC. At the time, Wang told us: Continue reading Montreal Heart Institute researcher dismissed following two retractions for image manipulation

Authors retract two JBC papers on how heart rhythms go awry; Montreal Heart Institute looking into why

The authors of two Journal of Biological Chemistry (JBC) studies of the molecular underpinnings of hearts whose rhythms have gone awry have retracted the papers, for reasons that are not completely clear.

The two papers are  “MicroRNA miR-133 represses HERG K+ channel expression contributing to QT prolongation in diabetic hearts,” published in 2007, and “Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart,” published in 2008.

This being the JBC, the retraction notices in the August 12, 2011 issue say nothing: Continue reading Authors retract two JBC papers on how heart rhythms go awry; Montreal Heart Institute looking into why