The first retraction has appeared for Alfred Fusco, a leading cancer researcher in Italy under criminal investigation for fraud.
Here’s the notice from the Journal of Clinical Investigation:
High-mobility group A1 inhibits p53 by cytoplasmic relocalization of its proapoptotic activator HIPK2
Giovanna Maria Pierantoni, Cinzia Rinaldo, Marcella Mottolese, Anna Di Benedetto, Francesco Esposito, Silvia Soddu and Alfredo Fusco
Published November 1, 2013
Original citation: J. Clin. Invest. 2007;117(3):693–702. doi:10.1172/JCI29852.
Citation for this retraction: J. Clin. Invest. 2013;123(11):4979. doi:10.1172/JCI73730.
It has come to our attention that multiple HMGA1 bands in the immunoblot images of Figure 1, A, B, and D, and Figure 3D have been inappropriately duplicated. In addition, the p53 blots in Figure 1, A and B, appear to represent a darker exposure of the same blot. The authors are unable to provide the original source files that were used to generate these data. While the authors maintain that these findings were confirmed in replicate experiments, the JCI Editorial Board has decided to retract this paper due to the evident manipulation in these figure panels. No issues have been raised in regard to any of the other data in this manuscript.
The authors regret the errors and concur with this course of action.
The paper has been cited 61 times, according to Thomson Scientific’s Web of Knowledge.
Der Spiegel has covered the Fusco case.