Anil Potti and colleagues retract ninth paper, this one in JCO
“An Integrated Genomic-Based Approach to Individualized Treatment of Patients With Advanced-Stage Ovarian Cancer” by Holly K. Dressman, Andrew Berchuck, Gina Chan, Jun Zhai, Andrea Bild, Robyn Sayer, Janiel Cragun, Jennifer Clarke, Regina S. Whitaker, LiHua Li, Jonathan Gray, Jeffrey Marks, Geoffrey S. Ginsburg, Anil Potti, Mike West, Joseph R. Nevins, and Johnathan M. Lancaster (J Clin Oncol 25:517-525, 2007)
The majority of the authors wish to retract this article because they have identified several instances of misalignment of genomic and clinical outcome data. Although a reanalysis of correctly aligned data still demonstrated a capacity to predict patient response to platinum-based therapy, the accuracy of these predictions has been reduced from 77.8% to 72.2%, and as a result, the original conclusions have been compromised. The authors deeply regret the impact of this action on the work of other investigators.
The following authors agreed with this retraction decision: Andrew Berchuck, Gina Chan, Janiel Cragun, Holly K. Dressman, Geoffrey S. Ginsburg, Jonathan Gray, Johnathan M. Lancaster, Jeffrey Marks, Joseph R. Nevins, Anil Potti, Mike West, and Regina S. Whitaker.
The following authors disagreed with this retraction decision: Andrea Bild, Jennifer Clarke, LiHua Li, and Jun Zhai.
The following author could not be reached for comment: Robyn Sayer.
This article was retracted on January 27, 2012.
The paper has been cited 114 times, according to Thomson Scientific’s Web of Knowledge. The retraction was first reported by The Cancer Letter.
The retraction, one of about a dozen that Duke says are expected, along with another dozen or so partial retractions, is the second one from the JCO for the group. At the time of the first, in November 2010, the journal told us:
Prior to retracting any paper, JCO must receive a signed statement from each author saying that he or she agrees that the article should be retracted and that the wording of the retraction is satisfactory to him or her.
We’ve tried reaching a few of the authors who didn’t agree to the retraction, and will update with anything we hear back.
hat tip: Steve McKinney