Nature cancer paper that raised animal welfare concerns is retracted

When Nature published a paper in 2011 describing a compound extracted from a pepper plant that appeared to kill cancer cells but leave healthy cells unscathed, it got some attention.

Of course, the news caught the media’s eye, but also that of other researchers, who have since jumped on the concept, and continued to study the effects of the compound — piperlongumine — on cancer, as well as other conditions.

But ever since the 2011 letter appeared, researchers have raised concerns about some of the figures — including one that showed mice with massive tumors, suggesting they had experienced an unreasonable amount of distress during the study. Nature has responded by issuing two lengthy correction notices in 2012 and 2015 — as well as an editorial that admitted the animals may have “experienced more pain and suffering than originally allowed for,” but did not warrant retracting, as the results remained “valid and useful.”

Today, the journal is retracting the paper, with the following brief notice:

Continue reading Nature cancer paper that raised animal welfare concerns is retracted

Meet two data sleuths who paid a steep price for raising concerns about a problematic paper

Researchers Malte Elson and Patrick Markey probably didn’t know what they were getting into when they first raised questions about a problematic study of the possible effects of violent video games.

Like many other data sleuths out there, they simply wanted to ensure the scientific record wasn’t muddied by problematic data — particularly in such a high-profile area with a potentially profound impact on policy.  Although their efforts ultimately paid off — the paper was retracted, and the first author lost her PhD — they also paid a price. Continue reading Meet two data sleuths who paid a steep price for raising concerns about a problematic paper

Former VA postdoc committed misconduct, banned from agency research for four years

A former postdoc at the U.S. VA Health Care System in Albuquerque, N.M., committed misconduct in three papers, the agency announced today.

Alba Chavez-Dozal, who studied the basic science underpinnings of infectious diseases, had three papers retracted between 2015 and 2016. In findings dated July 18, 2018, but released today, the VA said that Chavez-Dozal, “a post-doctoral research fellow who formerly held a VA without compensation appointment, engaged in research misconduct by intentionally and/or knowingly:” Continue reading Former VA postdoc committed misconduct, banned from agency research for four years

“[T]he data and findings…are unreliable:” Authors explain how a refutation came to be published in the same journal as the original

A rotifer, via Wikimedia

A group of tiny, all-female animals called bdelloid rotifers has long fascinated scientists. Among other questions, of course, is: Why haven’t they gone extinct, if they can’t mix up their genes? In 2016, a group of authors published a paper in Current Biology claiming to show that rotifers could swap DNA the way bacteria do. But a paper published earlier this month in the same journal found “clear evidence that the data and findings of [that study] are unreliable.” It’s unusual for a journal to publish a full paper clearly refuting another — and Current Biology left the original paper as is, without even a link to the new one. The authors of the new paper — Chris Wilson, Reuben Nowell, and Tim Barraclough, all of Imperial College London — explain how all of this came to pass, and why the authors of the original paper deserve praise.

RW: You and others refer to asexual rotifers as an “evolutionary scandal.” Can you explain? Continue reading “[T]he data and findings…are unreliable:” Authors explain how a refutation came to be published in the same journal as the original

Court orders journal to retract a paper after supplement seller sues

An Italian court has ordered a journal to retract a paper. But it hasn’t just yet.

Instead, the Journal of Ovarian Research has published an expression of concern about the 2012 paper, replete with obfuscating legal language.

Here’s the text:

Continue reading Court orders journal to retract a paper after supplement seller sues

Weekend reads: “Chronic compulsive writing syndrome;” a new way to respond to rejection; rewards for a center that doesn’t yet exist

Before we present this week’s Weekend Reads, a question: Do you enjoy our weekly roundup? If so, we could really use your help. Would you consider a tax-deductible donation to support Weekend Reads, and our daily work? Thanks in advance.

The week at Retraction Watch featured, unfortunately, a likely DDOS attack that kept our site dark for much of Tuesday and Wednesday. That means you may have missed this post, about the temporary withdrawal of a paper about a controversial “abortion reversal” method. But the week also featured the retraction of a paper about the Shroud of Turin, a researcher who lost a PhD despite the lack of any misconduct, and a new look at a study of whether spouses were more likely to cheat if their partners earned more than they did. Here’s what was happening elsewhere: Continue reading Weekend reads: “Chronic compulsive writing syndrome;” a new way to respond to rejection; rewards for a center that doesn’t yet exist

Medical ethicist: “I now understand that I should not have been re-using material”

Ezio Di Nucci

A researcher in medical ethics has retracted two papers within the last two years after admitting to reusing material from previous publications.

Ezio Di Nucci, based at the University of Copenhagen, claims he “had misunderstood the relevant practices.”

The first retraction, issued in 2017 by the Journal of Value Inquiry, notes the paper “constituted the third verbatim publication of the same text.” The paper “Strategic Bombing, Causal Beliefs, and Double Effect” has only been cited once since it was published in 2016, according to Clarivate Analytics’ Web of Science.

After that retraction, Di Nucci told us he requested the retraction of a second 2016 article, published by Minds and Machines. The retraction notice for “Habits, Priming and the Explanation of Mindless Action” — which has not yet been indexed — states that “the author misunderstood the practice of re-using one’s own material and apologizes for any inconvenience caused.”

Di Nucci told us:

Continue reading Medical ethicist: “I now understand that I should not have been re-using material”

Over authors’ objections, PLOS ONE retracts paper claiming Shroud of Turin showed evidence of trauma

A year ago, PLOS ONE published a study claiming that there was strong evidence that a person wrapped in the Shroud of Turin — according to lore, the burial shroud of Jesus Christ — had suffered “strong polytrauma.”

Today, they retracted it.

According to the retraction notice for “Atomic resolution studies detect new biologic evidences on the Turin Shroud,” Continue reading Over authors’ objections, PLOS ONE retracts paper claiming Shroud of Turin showed evidence of trauma

Are non-breadwinners more likely to cheat? 2015 study said yes; newly corrected version says “maybe”

A few years ago, you may remember some news headlines discussing a study that suggested people — especially men — are more likely to cheat if their spouses earn more money. Well, it turns out those findings are less convincing than they initially appeared. But they’re not getting retracted.

In a six-page correction notice, author Christin Munsch at the University of Connecticut explains that she made “several errors related to the coding of missing data,” which weakened most of her conclusions in the original paper.

The paper earned some attention from mainstream news outlets. For example, in 2015, The Washington Post wrote:

Continue reading Are non-breadwinners more likely to cheat? 2015 study said yes; newly corrected version says “maybe”

A university is revoking a student’s PhD — but not because of misconduct

Earlier this month, Tokushima University in Japan announced it was revoking a student’s PhD degree — but for a somewhat unusual reason.

The student didn’t appear to commit misconduct. Rather, the authors discovered a series of errors that invalidated the paper’s central conclusion.

The case has us wondering about how universities should respond when they discover some of a PhD student’s research is no longer valid — especially when there is no suspicion of misconduct.

Based on our Google translation of the more detailed description of what happened, the university concluded the problem was the result of the authors’ “simple mistakes:”

Continue reading A university is revoking a student’s PhD — but not because of misconduct