Retraction Watch

PLOS ONE has issued an expression of concern for a paper it published last month suggesting that vitamin D might protect against severe COVID-19. 

Central to the concerns is that the authors seem to have been too far out over their skis in asserting a link between the vitamin and the response to the infection. But as the EoC reveals, many of the potential problems can fairly be attributed to porous peer review as much as over-ambitious authors. 

The article, “Vitamin D sufficiency, a serum 25-hydroxyvitamin D at least 30 ng/mL reduced risk for adverse clinical outcomes in patients with COVID-19 infection,” came from a group at Tehran University of Medical Sciences in Iran and Boston University in the United States. According to the authors: 

In July 2014, Elisabeth Bik notified PLOS ONE that she’d found three papers in the journal by a group of researchers who had clearly manipulated figures in the articles. 

More than six years later, the journal has finally retracted the publications. 

The authors were affiliated with the Fourth Military Medical University in Shaanxi, China. The notice for 2013’s “Hyperthermia-induced NDRG2 upregulation inhibits the invasion of human hepatocellular carcinoma via suppressing ERK1/2 signaling pathway” refers to overlapping data in Figure 1A, similarities between data in Figure 1B and Figure 6C despite the fact that lanes “represent samples exposed to different experimental conditions,” and more: