Why — even after reforms for an episode involving bad statistics — is it so difficult to correct the sports medicine literature? Part 1

Matthew Tenan

Two years ago, following heated debate, a sports science journal banned a statistical method from its pages, and a different journal — which had published a defense of that method earlier — decided to boost its statistical chops. But as Matthew Tenan, a data scientist with a PhD in neuroscience relates in this three-part series, that doesn’t seem to have made it any easier to correct the scientific record. Here’s part one.

In‌ ‌July‌ ‌2019,‌ ‌my‌ ‌colleague‌ ‌‌Andrew‌ ‌Vigotsky‌‌ ‌contacted‌ ‌me.‌ ‌He‌ ‌was‌ ‌curious,‌ ‌he‌ ‌said,‌ ‌whether‌ ‌a‌ paper‌ ‌published‌ ‌in‌ ‌Sports‌ ‌Medicine‌ ‌had‌ ‌undergone‌ ‌statistical‌ ‌review ‌ ‌because‌ ‌he‌ ‌was‌ concerned‌ ‌about‌ ‌some‌ ‌of‌ ‌its‌ ‌claims.‌ ‌The‌ ‌link‌ ‌he‌ ‌sent‌ ‌me‌ ‌was‌ ‌to‌ ‌“‌A‌ ‌Method‌ ‌to‌ ‌Stop‌ ‌Analyzing‌ Random‌ ‌Error‌ ‌and‌ ‌Start‌ ‌Analyzing‌ ‌Differential‌ ‌Responders‌ ‌to‌ ‌Exercise‌,”‌ ‌a‌ ‌paper‌ ‌published‌ ‌on‌ June‌ ‌28,‌ ‌2019‌ ‌by‌ ‌‌Scott‌ ‌Dankel‌‌ ‌and‌ ‌‌Jeremy‌ ‌Loenneke‌.‌

As‌ ‌it‌ ‌happened,‌ ‌I‌ ‌knew‌ ‌that‌ ‌paper,‌ ‌and‌ ‌I‌ ‌had‌ ‌also‌ ‌expressed‌ ‌concerns‌ ‌about‌ ‌it‌ ‌–‌ ‌when‌ ‌I reviewed‌ ‌it‌ ‌before‌ ‌publication‌ ‌as‌ ‌one‌ ‌of‌ ‌the‌ ‌members‌ ‌of‌ ‌the‌ ‌journal’s‌ ‌editorial‌ ‌board.‌ ‌Indeed,‌ ‌I was‌ ‌brought‌ ‌on‌ ‌to‌ ‌the‌ ‌editorial‌ ‌board‌ ‌of‌ ‌‌Sports‌ ‌Medicine‌‌ ‌because‌ ‌the‌ ‌journal‌ ‌had‌ ‌recently‌ received‌ ‌a‌ ‌lot‌ ‌of‌ ‌bad‌ ‌press‌ ‌for‌ ‌publishing‌ ‌a‌ ‌paper‌ ‌about‌ ‌another‌ ‌“novel‌ ‌statistical‌ ‌method”‌ ‌with‌ significant‌ ‌issues and I had been a vocal critic of the sports medicine and sport science‌ field developing their own statistical methods that are not used outside of the field and validated by the wider statistics community.‌ ‌

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Journal retracts hotly contested paper on vaping and heart attacks

ecigarettereviewed.com via Wikimedia

The Journal of the American Heart Association (JAHA) today retracted a paper it published last year claiming that vaping was linked to heart attacks.

The paper, by Dharma Bhatta and Stanton Glantz of the University of California, San Francisco, has faced a barrage of criticism since its publication last June — and Glantz’s claims, in a blog post, that the study was “More evidence that e-cigs cause heart attacks.”

Brad Rodu, a professor at the University of Louisville who comments frequently on vaping, asked the journal to retract the study shortly after it was published. The study, he said, had failed to account for which happened first — heart attacks or vaping. The contretemps was the subject of a July 2019 story by USA Today:

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WHO formally retracts opioid guidelines that came under fire

via Flickr

The World Health Organization has officially retracted its controversial guidelines on the use of opioid analgesics. 

The agency’s move applies to two statements, issued in 2011 and 2012. Last June, WHO announced that it was “discontinuing” the guidelines in the wake of a critical report which said the documents were heavily tainted by commercial bias. According to a BMJ story published at the time

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Prominent cancer researcher loses nine papers, making 10

Andrew Dannenberg (credit Patricia Kuharic)

The Journal of Biological Chemistry (JBC) has retracted nine papers in bulk by a group of cancer researchers in New York led by the prominent scientist Andrew Dannenberg

The work of Dannenberg’s group at Weill Cornell — and the figures in particular — has been the subject of scrutiny on PubPeer for more than two years. 

The group also lost an article more than a decade ago in The Lancet, bringing their total so far to 10. Cancer Discovery subjected a paper to an expression of concern in August. Much of the tainted work was funded by grants from the U.S. government, as well as from funding authorities in other countries.  

According to the notice for 2014’s “p53 protein regulates Hsp90 ATPase activity and thereby Wnt signaling by modulating Aha1 expression“:

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How a plagiarized eye image in the NEJM was discovered

via Wikimedia

The Images in Clinical Medicine section of the New England Journal of Medicine (NEJM) is prime real estate for physicians and others wanting to share a compelling picture with their colleagues. But earlier this month, an eye specialist in Michigan saw double when he looked at the Dec. 5, 2019, installment of the feature. 

Depicted was a picture from a pair of eye specialists in India who claimed to have seen a case of a person who’d suffered retinal bleeding after having been struck in the eye by a tennis ball:

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‘A long and lonely process:’ Whistleblowers in a misconduct case speak out

Last week, we reported on a case at the University of Leiden in which the institution found that a former psychology researcher there had committed research misconduct. In the anonymized report — which we were able to confirm regarded Lorenza Colzato, who is listed as a faculty member at Ruhr University in Bochum and at TU Dresden — the university found a lack of ethics approval for some studies and fabricating results in some grant applications. We asked the three whistleblowers in the case — Bryant Jongkees, Roberta Sellaro, and Laura Steenbergen — to reflect on their experiences. (We should note that they did not confirm it was Colzato named in the report.)

Retraction Watch (RW): What prompted you to come forward?

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Authors retract two studies on high blood pressure and supplements after realizing they’d made a common error

A group of researchers from Iran, Italy and the UK have retracted two meta-analyses on supplements and high blood pressure after making what a statistics expert calls a common error.

Both papers were originally published in the Journal of Human Hypertension. Here’s the retraction notice for “Elevated blood pressure reduction after α-lipoic acid supplementation: a meta-analysis of randomized controlled trials:”

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‘We decided to play it safe.’ Journal doesn’t retract paper even though the authors neglected to mention that they didn’t do the experiments themselves.

via James Heilman/Wikipedia

An eye journal has issued an expression of concern for a paper on glaucoma that, given the litany of problems with the data, could well have been retracted. Not least of the issues: The authors admitted to using an outside firm to conduct experiments they’d tried to pass off as having done themselves. 

The article, “Fisetin rescues retinal functions by suppressing inflammatory response in a DBA/2J mouse model of glaucoma,” came from a group at People’s Hospital of Rizhao. It appeared online last February in Documenta Ophthalmologica, the journal of the International Society for Clinical Electrophysiology and Vision. 

According to the researchers: 

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Reviewers asked authors to change their study design. It apparently didn’t go well.

In what the editor of a psychiatry journal says in an unusual case, the authors of a paper on treatments for depression have retracted it after being alerted to “inconsistencies” stemming from a change to their study design that the peer reviewers had requested. 

Here’s the retraction notice, in The Journal of Nervous and Mental Disease:

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What’s the hernia? Authors lose surgery paper for miscounting cases

Inguinal hernia

A group of pediatric surgeons in China has lost their 2016 paper on a technique for repairing abdominal defects in children because they apparently had trouble keeping those defects straight. 

The article, “A new technique for extraperitoneal repair of inguinal hernia,” appeared in the Journal of Surgical Research, an Elsevier title. The authors reported that a laparoscopic method of repairing inguinal hernias in children was superior to conventional, open surgery. According to the authors, they had nearly 1,900 patients to prove their point. 

But as the retraction notice indicates, the numbers didn’t add up. 

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