University cuts anesthesiology researcher’s funding amid four retractions

An anesthesiologist who had his funding revoked for fabricating data has earned a fourth retraction for publishing the same data in two Springer Nature journals. 

Wen-fei Tan, an anesthesiologist at The First Hospital of China Medical University in Shenyang, is the first author of the recently retracted paper “Changes in the first postoperative night bispectral index of patients after thyroidectomy with different types of primary anesthetic management: a randomized controlled trial,” published in the Journal of Clinical Monitoring and Computing (JCMC), a Springer Nature journal, in 2017. It has been cited four times, according to Clarivate’s Web of Science. 

The retraction notice states: 

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How journal editors kept questionable data about women’s health out of the literature years before retractions

John Carlisle

In July of 2017, Mohamed Rezk, of the department of obstetrics and gynecology at Menoufia University in Egypt, submitted a manuscript to the journal Anesthesia with a colleague. 

The manuscript, “Analgesic and antiemetic effect of Intraperitoneal magnesium sulfate in laparoscopic salpingectomy: a randomized controlled trial,” caught the attention of John Carlisle, an editor at the journal whose name will be familiar to Retraction Watch readers as the sleuth whose statistical analyses have identified hundreds of papers with implausible clinical trial data

The baseline data appeared unremarkable, Carlisle told us, but the same wasn’t true of the outcomes data. Of 24 values that could have been odd or even numbers, all of them were even. 

The probability of that was “​​0.000000000000000000000 something,” Carlisle said. 

Continue reading How journal editors kept questionable data about women’s health out of the literature years before retractions

More than 100 of an anesthesiologist’s papers retracted

Showa University Hospital

There’s a new entry on the Retraction Watch Leaderboard. And this one is also the fourth member of the Retraction Watch Century Club.

An anesthesiology researcher in Japan is now up to 117 retractions – putting him third on our list of most-retracted authors.

Hironobu Ueshima, formerly of Showa University Hospital in Tokyo, was found to have committed misconduct in 142 papers, according to a pair of investigations, one by his erstwhile institution and another by the Japanese Society of Anesthesiologists (JSA). We first reported on the existence of the investigation in June 2020, some three months after Australian anesthesiologist and journal editor John Loadsman raised concerns with journals involved in the case. 

Continue reading More than 100 of an anesthesiologist’s papers retracted

Four years after anesthesiology society’s request, four articles remain unretracted

Three years ago, we wrote that the Japanese Society of Anesthesiologists had in 2017 asked several journals to retract a total of nine papers by Yuhji Saitoh, formerly of Yachiyo Medical Center and Tokyo Women’s Medical University. 

According to the society, Saitoh had committed ethics violations in 10 articles, three of which had already been retracted and seven of which remained in the wild. (Saitoh had been a frequent co-author with Yoshitaka Fujii, currently our record holder for most retractions by a single researcher — 183 — but the JSA report found that he’d committed misconduct on his own, too. He has 53 retractions, according to our count, placing him seventh on our leaderboard.)

Four of those 10 articles appeared in the Canadian Journal of Anesthesia and two others were published in the British Journal of Anaesthesia.  (The seventh paper, in the Fukushima Journal of Medical Sciences, has since been retracted.)

Continue reading Four years after anesthesiology society’s request, four articles remain unretracted

Meet a sleuth whose work has led to the identification of hundreds of fraudulent papers

John Loadsman

Last month, Retraction Watch reported on the case of Hironobo Ueshima, an anesthesiology researcher found guilty of misconduct in more than 140 papers. A journal editor, John Loadsman, was the first to suspect there were issues in Ueshima’s work. But this was hardly the first time Loadsman had been the canary in the coal mine of the anesthesiology literature, placing him squarely on our ever-growing list of scientific sleuths that includes Elisabeth Bik, who has been in the news recently because of threats. In this Q&A, we ask Loadsman what happened in the Ueshima case, and for his sense of how big a problem fraud in the literature is.

Retraction Watch (RW): You were the editor who first spotted problems with Ueshima’s work. Walk us through how you cracked the case. What made you suspect that his data were not kosher?

Continue reading Meet a sleuth whose work has led to the identification of hundreds of fraudulent papers

Anesthesiology researcher guilty of misconduct in more than 140 papers: Investigation

Showa University Hospital, via Wikimedia

A Japanese anesthesiologist has been found guilty of fabricating data and other misconduct in 142 articles, leading to his termination and the sanction of several of his co-authors. 

Showa University says its investigation into Hironobu Ueshima, the existence of which we first reported on last June, found that the prolific researcher had doctored his results, falsified his findings and tinkered with authorship.

The university’s report on the case is available here, in Japanese, and a similar report from the Japanese Society of Anesthesiologists is available here in English. The JSA report cites 142 papers — including 120 letters to the editor, 12 original papers, and 9 case reports — with evidence of misconduct including fabricated data and improper authorship. The investigation also found evidence of misconduct in several unpublished studies by Ueshima. By our count, he has six retractions to date.

Continue reading Anesthesiology researcher guilty of misconduct in more than 140 papers: Investigation

Drug company withdraws court motion requesting retraction of papers critical of its painkiller

A drug maker has blinked in a lawsuit against the leading anesthesiology society in the United States, along with several anesthesiology researchers, who it claims libeled the company in a series of articles and other materials critical of its main product. 

As we reported last month, Pacira Biosciences, which makes the local anesthetic agent Exparel, field the suit in federal court in April, alleging that the American Society of Anesthesiologists (ASA), the editor of its flagship journal, Anesthesiology, and others, were unfairly targeting the drug.

The company asked the court for a preliminary injunction to retract two papers and an editorial about Exparel that Anesthesiology published in February. But on May 7,  Pacira withdrew the motion, about a week after the ASA filed its own motion calling for a quick hearing on the merits of the company’s motion. 

According to an unusually forceful statement (for a medical society) from the ASA

Continue reading Drug company withdraws court motion requesting retraction of papers critical of its painkiller

“We didn’t want to hurt them. We are polite”: When a retraction notice pulls punches

via Flickr

A group of anesthesiology researchers in China have lost their 2020 paper on nerve blocks during lung surgery after finding that the work contained “too many” errors to stand. But after hearing from the top editor of the journal, it’s pretty clear “too many errors” was a euphemism for even worse problems.

The article, “Opioid-sparing effect of modified intercostal nerve block during single-port thoracoscopic lobectomy: A randomised controlled trial,” came from a team at Anhui Medical University. The senior author was  Guang-hong Xu. The paper appeared online in early December in the European Journal of Anaesthesiology

At which point it caught the attention of a reader in Australia, who emailed the journal to  point out fishiness in the data. 

Charles Marc Samama, the editor-in-chief of the EJA, told us:

Continue reading “We didn’t want to hurt them. We are polite”: When a retraction notice pulls punches

Painfully awkward: Duplicate anesthesiology study retracted

Sugammadex, via Wikimedia

A study that compared drugs used to reverse the effects of relaxants for surgery has been retracted because the majority of the results were already published.

The study, “Comparison of sugammadex and pyridostigmine bromide for reversal of rocuronium-induced neuromuscular blockade in short-term pediatric surgery,” appeared in the journal Medicine in February 2020.

The work found that the drug sugammadex worked faster than pyridostigmine in children undergoing surgery, and doesn’t appear to have anything wrong with it. But a study with the same authors and same name (barring a single uncapitalized letter) had already been published in the journal Anesthesia and Pain Medicine on July 31, 2019.

Continue reading Painfully awkward: Duplicate anesthesiology study retracted

Leading anesthesiologist retracts paper after reader “noticed that the statistical approach was sub-optimal”

An anesthesia journal has retracted a 2020 paper by a group from China, Turkey and the United States after a post-publication review discovered issues with the analysis. 

According to the notice, in the European Journal of Anaesthesiology:  

Continue reading Leading anesthesiologist retracts paper after reader “noticed that the statistical approach was sub-optimal”