Retraction for ‘unsound’ analysis was ‘disproportionate and discouraging,’ author says

The editors of Scientific Reports have retracted an article on burnout because the statistical analysis of its main finding was “unsound.” But the authors dispute the editors’ take on the statistics and claim a mistake in the paper triggered an unfair review.

For the paper, published in November, the authors measured concentrations of cortisol in hair samples from nearly 500 healthcare workers in Buenos Aires to study the effect of the COVID-19 pandemic on chronic stress and burnout. The analysis hinged on a statistical method called mediation analysis.

“Mediation analysis is a method to understand how one thing causes another by looking at what happens in between,” said lead author Federico Fortuna, of the Institute of Physiopathology and Clinical Biochemistry at the University of Buenos Aires. “In our study, we examined whether depersonalisation mediates the relationship between hair cortisol — a biological stress marker — and emotional exhaustion, a key psychological symptom of burnout.”

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When it comes to conflicts of interest, affiliations are apparently no smoking gun

Seven papers on various aspects of vaping and cigarettes published in Toxicology Reports listed each authors’ affiliation –  the tobacco company Philip Morris International – when they originally appeared in the journal between 2019 and 2023. And all but one article disclosed the funding for the research originated from the company. 

That apparently wasn’t enough for the journal.

Toxicology Reports has issued a correction to add those affiliations as a conflict of interest. The statements were “missing or incorrect” in the original papers, according to the correction notice, published in the June 2025 issue of Toxicology Reports. In addition to reiterating that the authors work for PMI, the correction also adds to the conflict of interest statements that the authors were funded by the company and used its products in the research.

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Viral paper on black plastic kitchen utensils earns second correction

The authors of a paper that went viral with attention-grabbing headlines urging people to throw out their black plastic kitchen tools have corrected the work for a second time.

But a letter accompanying the correction suggests the latest update still fails “to completely correct the math and methodological errors present in the study,” according to Mark Jones, an industrial chemist and consultant who has been following the case. “The errors are sufficient to warrant a restating of the abstract, sections of the paper and conclusions, if not a retraction.”

The paper, “From e-waste to living space: Flame retardants contaminating household items add to concern about plastic recycling,” originally appeared in Chemosphere in September. The study authors, from the advocacy group Toxic-Free Future and the Amsterdam Institute for Life and Environment at Vrije Universiteit Amsterdam, looked for the presence of flame retardants in certain household plastic items, including toys, food service trays and kitchen utensils. 

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Science issues correction on a paper after repeat experiments and misconduct finding

Science has changed an expression of concern on a 2022 paper to an erratum after removing one of the coauthors — who was found to have committed misconduct — and allowing the researchers to repeat experiments.

The paper, “Structural basis for strychnine activation of human bitter taste receptor TAS2R46,” has been cited 68 times, according to Clarivate’s Web of Science. 

Two months after publishing the article in September 2022, Science issued an editorial expression of concern, stating a post-publication analysis had found one figure with “potential discrepancies.”

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Apparent NCI director candidate wants ‘open, respectful’ post-publication peer review while promoting anonymous site that calls sleuths a ‘mob’

Wafik S. El-Deiry

Brown University physician-scientist Wafik El-Deiry has been a longtime critic of the post-publication forum PubPeer, where 75 of his papers have been flagged. For example, in an April post on X, formerly Twitter, he stated, “It is not good that PubPeer has been weaponized and has become tyrannical.” In July 2024, he referred to the emails authors receive when someone posts a comment about their papers as being “under attack by PubPeer and their anonymous mob.”

PubPeer, started in 2012, won the 2024 Einstein Award For Promoting Quality in Research. (Disclosure: Our co-founder Ivan Oransky is a volunteer member of the board of directors of the PubPeer Foundation.)

In April, a site called Science Guardians, an “online journal club” with remarkable similarities – but also key differences – to PubPeer, launched what it called an “investigation” into PubPeer. Since then the anonymous account has posted numerous posts on X critiquing PubPeer while promising to reveal the “perpetrators of the PubPeer Network Mob.” 

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10 years after the downfall of a same-sex marriage canvassing study, tenure, some better practices — and an engagement

A study on how conversations can change minds grabbed headlines when it was published — and again five months later when retracted.

“Gay Advocates Can Shift Same-Sex Marriage Views,” read the New York Times headline. “Doorstep visits change attitudes on gay marriage,” declared the Los Angeles Times. “Cure Homophobia With This One Weird Trick!” Slate spouted.

Driving those headlines was a December 2014 study in Science, by Michael J. LaCour, then a Ph.D. student at the University of California, Los Angeles, and Donald Green, a professor at Columbia University.

Researchers praised the “buzzy new study,” as Slate called it at the time, for its robust effects and impressive results. The key finding: A brief conversation with a gay door-to-door canvasser could change the mind of someone opposed to same-sex marriage. 

By the time the study was published, David Broockman, then a graduate student at the University of California, Berkeley, had already seen LaCour’s results and was keen to pursue his own version of it. He and fellow graduate student Joshua Kalla had collaborated before and wanted to look more closely at the impact canvassing could have on elections. But as the pair deconstructed LaCour’s study to figure out how to replicate it, they hit several curious stumbling blocks. And when they got a hold of LaCour’s dataset, or replication package, they quickly realized the results weren’t adding up. 

Continue reading 10 years after the downfall of a same-sex marriage canvassing study, tenure, some better practices — and an engagement

Fourth retraction for Italian scientist comes 11 years after sleuths flagged paper

PLOS One has retracted a 2011 paper first flagged for image issues 11 years ago. The retraction marks the fourth for the paper’s lead author, Gabriella Marfè of the University of Campania “Luigi Vanvitelli,” in Caserta, Italy. 

Involvement of FOXO Transcription Factors, TRAIL-FasL/Fas, and Sirtuin Proteins Family in Canine Coronavirus Type II-Induced Apoptosis,” has been cited 41 times, according to Clarivate’s Web of Science. 

Elisabeth Bik flagged the article on PubPeer in 2014 for apparent image manipulation and duplication in six figures. In a 2019 email to PLOS staff, pseudonymous sleuth Claire Francis drew attention to Bik’s findings. The journal retracted the paper on May 6 of this year.

Continue reading Fourth retraction for Italian scientist comes 11 years after sleuths flagged paper

IQ study retracted in fallout from decades-old misconduct report

The authors of a paper on how motivation influences  intelligence test scores have retracted their paper following the retraction of a 50-year-old study included in their analysis. 

Part meta-analysis and part longitudinal study, “Role of test motivation in intelligence testing” appeared in Proceedings of the National Academy of Sciences in 2011. The meta-analysis portion included a 1978 paper by Stephen Breuning, a child psychologist who was the subject of 1987 report from the National Institute of Mental Health that found he “knowingly, willfully, and repeatedly” engaged in research misconduct and fabricated results in 10 NIMH funded articles.

As we reported earlier this year, six of Breuning’s papers have been retracted, including one last December. That article, published in 1978 in the Journal of School Psychology, found record albums, sporting event tickets, portable radios, and other incentives boosted scores on IQ tests.

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‘More of the same’: Journals, trade website refuse to correct critiques of book on Alzheimer’s fraud

Amyloid-beta plaques (brown) and tau protein tangles (blue). Credit: National Institute on Aging/NIH

Investigative journalist Charles Piller’s latest book, Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer’s, came out in February. It details the work of Matthew Schrag, a neurologist at Vanderbilt University in Nashville, Tenn., and other sleuths who uncovered evidence of problems in hundreds of research papers about the neurologic condition. 

Most reviews and coverage have been positive, Piller said. But some Alzheimer’s researchers have criticized the book in reviews published in JAMA, The Lancet Neurology, and the website Alzforum, which hosts news and commentary on Alzheimer’s research. 

Piller and Schrag say they respect that others are entitled to their opinions, but expressed concern that some of these reviews contain inaccuracies that downplay their findings. And the journals and Alzforum have refused to publish responses they submitted or make corrections they requested. 

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Genentech authors flip PNAS study from corrected to retracted following Retraction Watch coverage

The authors of a 2006 paper have retracted their article following an extensive correction in January – and a Retraction Watch story noting the correction missed at least one additional issue with the work.

Death-receptor activation halts clathrin-dependent endocytosis,” published in July 2006 in Proceedings of the National Academy of Sciences, has been cited 99 times, according to Clarivate’s Web of Science. Most of the authors were affiliated with the biotech company Genentech. 

As we previously reported, commenters on PubPeer raised issues about possible image duplications, spurring the authors to review the work. The January correction addressed about two dozen instances of image splicing and duplication in five of the paper’s figures. The notice stated the authors repeated the experiments for a manuscript posted on bioRxiv in October 2024. “The new data confirms the original results, reaffirming the experimental conclusions,” the authors wrote in the correction notice. 

Continue reading Genentech authors flip PNAS study from corrected to retracted following Retraction Watch coverage