Macchiarini may be dismissed from Karolinska; dean of research resigns

Paolo Macchiarini
Paolo Macchiarini

There’s more news to report on the story of surgeon Paolo Macchiarini, who’s been dogged by allegations of misconduct.

After the Karolinska Institutet (KI) announced it would not extend his contract and that he needed to “phase out” his research by November, it has now announced it may dismiss him.

In addition, Hans-Gustaf Ljunggren, KI’s Dean of Research, has resigned.

Here’s the statement we received from a KI spokesperson:

Continue reading Macchiarini may be dismissed from Karolinska; dean of research resigns

Karolinska vice-chancellor resigns following criticism of Macchiarini investigation

Anders Hamsten
Anders Hamsten

Anders Hamsten announced he would be resigning as vice-chancellor from Karolinska Institutet (KI) in the early hours of Saturday, February 13.

In a press release we received at 12:16 a.m. local time in Stockholm, Hamsten issued the following statement:

Following the criticism on the so called Macchiarini affair at KI I conclude it will be hard for me to serve as Vice-Chancellor with the strength and credibility this university needs. I will therefore leave office.

Good thing we published a primer on the whole story a few hours ago. To recap: Continue reading Karolinska vice-chancellor resigns following criticism of Macchiarini investigation

Karolinska orders new investigation of trachea surgeon Macchiarini

Paolo Macchiarini
Paolo Macchiarini

The Karolinska Institutet University Board announced today it was issuing a new external investigation of trachea surgeon Paolo Macchiarini, looking into questions about his recruitment and the handling of previous allegations of misconduct.

According to a press release:

The University Board deems such an inquiry to be an important part of restoring the confidence of the public, the scientific community, staff and students in the university.

The board hopes to appoint the investigative team, which will not consider “matters of a medical-scientific nature,” next week. The goal is to conclude the investigation by the summer.

There were many signs this was coming:  Continue reading Karolinska orders new investigation of trachea surgeon Macchiarini

Karolinska won’t extend star surgeon Macchiarini’s contract

dr-paolo-macchiarini
Paolo Macchiarini

Karolinska Institutet announced today it would not extend the contract of star surgeon Paolo Macchiarini. He has been instructed to “phase out” his research from now until November 30.

According to a press release issued today: Continue reading Karolinska won’t extend star surgeon Macchiarini’s contract

Trachea surgeon Macchiarini acted “without due care,” but is not guilty of misconduct: Karolinska

Paolo Macchiarini
Paolo Macchiarini

Following an investigation, Karolinska Institutet has found that surgeon and visiting professor Paolo Macchiarini acted in some cases “without due care,” but that his behavior “does not qualify as scientific misconduct.”

Karolinska’s Vice Chancellor has also recommended that Macchiarini submit an unspecified number of corrections “to clarify and rectify the failings that the inquiry has brought to light.”

Macchiarini is most well-known for pioneering the creation of tracheas from cadavers and patients’ own stem cells. However, the glow of his success was diminished somewhat after four Karolinska surgeons filed a complaint, alleging Macchiarini had downplayed the risks of the procedure and not obtained proper consent, among other accusations.

An external review by Bengt Gerdin of Uppsala University concluded in May that Continue reading Trachea surgeon Macchiarini acted “without due care,” but is not guilty of misconduct: Karolinska

Journal of Neuroscience retracts plasticity paper for “substantial data misrepresentation”

jneuroscicoverThe Journal of Neuroscience has retracted a 2012 paper by a group from Sweden’s Karolinska Institutet for what appears to be research misconduct. But more on that in a moment.

The article, “The Existence of FGFR1-5-HT1A Receptor Heterocomplexes in Midbrain 5-HT Neurons of the Rat: Relevance for Neuroplasticity,” came from the lab of Kjell Fuxe, whose interests include Parkinson’s disease, addiction and depression. The first and second authors, Dasiel Oscar Borroto-Escuela and Wilber Romero-Fernandez, are listed as being post-docs in the lab.

According to the notice: Continue reading Journal of Neuroscience retracts plasticity paper for “substantial data misrepresentation”