Author: Megan Scudellari

Third retraction for GWU biologist as university seeks to dismiss his $8 million lawsuit

Rakesh Kumar, via George Washington University
Rakesh Kumar, via George Washington University

Cancer biologist Rakesh Kumar has chalked up another retraction, this time for “identical,” “duplicated,” and “replicated” figures and images.

It comes on the heels of a flurry of motions in Kumar’s $8 million lawsuit against his employer, George Washington University, for breach of contract and emotional distress because it removed him as department chair last year and placed his research on hold. Kumar remains employed by the university.

The retracted paper, published in Development in 2004, “Metastasis-associated protein 1 deregulation causes inappropriate mammary gland development and tumorigenesis,” analyzed the role of a protein, MTA1, in mammary gland development and cancer. It was published while Kumar was at M.D. Anderson in Houston, and has been cited 81 times, according to Thomson Scientific’s Web of Knowledge.

By our count, Kumar now has three retractions and five corrections. Numerous anonymous comments on Kumar’s papers have been posted on PubPeer, many of them critiquing images. Here’s the complete notice from Development: Continue reading Third retraction for GWU biologist as university seeks to dismiss his $8 million lawsuit

Dude, whose gene is that? Genetics paper retracted for lack of permission

pbrPlant Biotechnology Reports is retracting a 2009 paper by a group of researchers in South Korea because the authors submitted the article “without the permission” of the owner of a gene used in the study.

The paper abstract is no longer online, though the Committee on Publication Ethics (COPE) recommends that retraction notices be linked to the retracted article wherever possible. So we can’t even tell you what the paper is about, outside of its title: “T1 transgenic tobacco plants carrying multicopy T-DNAs at the same locus exhibit various expression levels of transgenes.”

Here’s all we’ve got—the retraction notice itself: Continue reading Dude, whose gene is that? Genetics paper retracted for lack of permission

NIH cancer paper retracted for faked data

JCIFollowing an investigation into research misconduct, the Journal of Clinical Investigation has retracted a cancer genetics paper from a laboratory at the National Institutes of Health due to “data falsification and fabrication” of four figures and a table in the paper.

The paper, “FOXO3 programs tumor-associated DCs to become tolerogenic in human and murine prostate cancer,” describes an overexpressed gene in mouse prostate cancers that appears to suppress immune system cells.

The journal retracted the paper following an investigation into author Stephanie K. Watkins, then a postdoctoral fellow at the National Cancer Institute. According to a NIH press release released about the study in March 2011, the work “has led to the submission of a patent application by the NIH on behalf of Hurwitz and Watkins to target FOXO3 as a way to boost immune responses in cancer and to silence excessive immune responses in autoimmune diseases.” We found an NIH record of the patent application, but no record of an approved patent at the United States Patent and Trademark Office under either Hurwitz or Watkins’ names.

The paper has been cited 62 times, according to Thomson Scientific’s Web of Knowledge. Here’s the full notice: Continue reading NIH cancer paper retracted for faked data

“Unreliable” data suffocates third paper for Duke pulmonary team

ajrcmbOnce again, a team of Duke University scientists has retracted a paper, this time due to “unreliable” figure data.

With co-authors at the U.S. Environmental Protection Agency, the Duke team has withdrawn a paper from the American Journal of Respiratory Cell and Molecular Biology after concern about data in three figures led them to repeat one of their main experiments. They subsequently found “no evidence” supporting their previous conclusion.

By our count, it is the third retraction from a team that includes William Foster, a pulmonary researcher at the Duke Medical Center. The Duke team retracted a paper in 2013 on a related topic—the effect of early life ozone exposure on airways—from the Journal of Applied Physiology when it was discovered that, familiarly, data in a figure were “unreliable”. Recently, they also retracted a PNAS paper on asthma treatment earlier this month, due to missing primary data and mismatched data from two sources.

Continue reading “Unreliable” data suffocates third paper for Duke pulmonary team

Chem paper fails to catalyze when wrong files are “inadvertently used”

joceah_v080i008.inddThree chemists at the Indian Institute of Technology Guwahati in India have retracted a paper from the Journal of Organic Chemistry because the “incorrect files were inadvertently used.”

The article, “Room-Temperature Cu(II)-Catalyzed Chemo- and Regioselective Ortho-Nitration of Arenes via C–H Functionalization,” described a protocol to perform nitration — the addition of nitro groups onto an organic compound — using an inexpensive copper catalyst.

All three authors signed the one-sentence notice:

Continue reading Chem paper fails to catalyze when wrong files are “inadvertently used”

Chinese medical case study erased after guardian consent withdrawn

JMCRThe editor of the Journal of Medical Case Reports, a BioMed Central title, has retracted and removed a case study of a novel surgical treatment after the patient’s legal guardian withdrew consent post-publication.

The paper, “Novel two-stage surgical treatment for Cantrell syndrome complicated by severe pulmonary hypertension: a case report,” describes the treatment of a six-month-old Han Chinese girl suffering from a rare combination of birth defects called Cantrell syndrome, complicated by pulmonary hypertension.

The original article, published in March 2014, has been removed from the journal’s website, though the abstract can be read on PubMed. It is unclear whether the authors, the child’s guardian, or some other party informed the editor of the withdrawal of consent.

The brief notice offers few details:

Continue reading Chinese medical case study erased after guardian consent withdrawn