The hits keep coming for University of Maryland researcher Anil Jaiswal.
The latest retraction for the cell biologist is in Cancer Research, for a 2007 paper about ways in which the cell tries to protect the tumor suppressor p53. Like the first Jaiswal retraction we covered, the latest notice specifically taps figure duplication as the cause of death, “as a result of an error.” The other two retractions gave no explanation for the withdrawal.
Here’s the notice:
The authors wish to retract the article titled “NRH:Quinone Oxidoreductase 2 and NAD(P)H:Quinone Oxidoreductase 1 Protect Tumor Suppressor p53 against 20S Proteasomal Degradation Leading to Stabilization and Activation of p53,” which was published in the June 1, 2007, issue of Cancer Research (1). As a result of an error, the p53 and NQO2 panels in Fig. 6A were reused from Fig. 3B of the article titled “Lower induction of p53 and decreased apoptosis in NQO1-null mice lead to increased sensitivity to chemical-induced skin carcinogenesis” by Iskander and colleagues (2).
Two of the four authors agreed to this Retraction. Attempts on the part of the journal office to contact Xing Gong and Labanyamoy Kole were unsuccessful.
Karim Iskander
Onyx Pharmaceuticals, Inc., Houston, Texas
Anil K. Jaiswal
Department of Pharmacology, University of Maryland School of Medicine, Baltimore, Maryland.
We’ve reached out to Jaiswal, the University of Maryland’s office of research integrity, and the journal, and will update if we hear back.
The paper has been cited 79 times, according to Google Scholar.
It took UMB over 9 months from Jaiswal’s first retraction to remove him from being co-director of the Program in Toxicology, and re-assign all his grad students to other faculty. The school never gave a reason and waited until several .weeks into the fall 2014 term, after Jaiswal hosted a meeting to welcome new and returning students. But now 5 months later his UMB website still lists him as co-director of the program
http://medschool.umaryland.edu/FACULTYRESEARCHPROFILE/viewprofile.aspx?id=9727
He is still a full professor but no longer teaches or supervises students.
There is a number of Jaiswal papers flagged on PubPeer for potential manipulations. Hopefully U of Maryland is aware of this phenomenon.
https://pubpeer.com/search?q=jaiswal&sessionid=EDAF2715C4ABA992F259&commit=Search+Publications
The length of Anil Jaiswal’s bioliography would impress many.
Free Radic Biol Med. 2012 Nov 15;53(10):1886-93. doi: 10.1016/j.freeradbiomed.2012.08.584. Epub 2012 Aug 31.
NAD(P)H:quinone oxidoreductase 1 protects bladder epithelium against painful bladder syndrome in mice.
Patrick BA1, Das A, Jaiswal AK.
Author information
Department of Pharmacology and Experimental Therapeutics, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
A 2013 corrigendum for figure 1 has been published for this paper.
http://www.sciencedirect.com/science/article/pii/S0891584913000725
A 2014 corrigendum has been published for figure 5 of this paper.
http://www.sciencedirect.com/science/article/pii/S0891584914004377
Three 2016 Expressions of Concern published for JBC papers.
http://www.jbc.org/content/291/3/1199.1.full.pdf+html
Was there ever any feedback from Anil K Jaiswal, or from Maryland University’s office of Research Integrity?