Retraction Watch

Tracking retractions as a window into the scientific process

Archive for the ‘anesthesia retractions’ Category

Lancet retracts (and replaces) paper a year after authors report error that changes “all numbers”

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In March 2016, researchers in Switzerland and Canada published a meta-analysis in The Lancet, exploring the optimal painkiller and dose for treating pain in knee and hip osteoarthritis. Soon after, the authors were informed of an error that would change “all numbers” in a paper that may influence clinical practice.

The authors contacted The Lancet immediately, in July 2016, to inform them of the issue. Sven Trelle, the paper’s corresponding author, also told us: Read the rest of this entry »

Written by Victoria Stern

July 10th, 2017 at 11:02 am

Former prof fudged dozens of images, says university

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On Dec. 2, 2013, Alison Lakin, the research integrity officer at the University of Colorado Denver, received a concerning email.

The emailer was alleging several problems in a 2012 paper in the Journal of Clinical Investigation, co-authored by one of its high-profile faculty members. Lakin discussed the allegations with some administrators and agreed they had merit; Lakin sequestered an author’s laptop and other materials. Over the next few months, the university learned of additional allegations affecting other papers — and discovered even more serious problems in the JCI paper. Namely, the first author had inserted changes to 21 figures in the paper after submitting it, without alerting the other authors, journal, or reviewers.

That journal retracted the paper this month, citing numerous problems:

Read the rest of this entry »

Anesthesiology society bans co-author of researcher with record-number of retractions

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The Japanese Society of Anesthesiologists has permanently banned a co-author of notorious fraudster Yoshitaka Fujii, after investigating many of his publications for alleged fraud.

According to the announcement last month (in Japanese), a committee investigated approximately 40 publications by Yuhji Saitoh of Yachiyo Medical Center and Tokyo Women’s Medical University in Japan. Saitoh resigned from the society once the investigation started; after the committee found evidence of data manipulation and fraud, the society decided it would permanently ban him as a member.

Saitoh was a frequent co-author of Yoshitaka Fujii, an anesthesia researcher with a record-breaking number of retractions (more than 180). Last year, anesthesia fraud sleuth John Carlisle and a co-author analyzed Saitoh’s papers — including many he didn’t co-author with Fujii — and concluded there was very low likelihood the sampling had been conducted randomly, among other potential concerns.

On May 9, the Japanese Society of Anesthesiologists issued the following statement, which we translated:

Read the rest of this entry »

Written by Alison McCook

June 6th, 2017 at 11:30 am

Two in 100 clinical trials in eight major journals likely contain inaccurate data: Study

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A sweeping analysis of more than 5,000 papers in eight leading medical journals has found compelling evidence of suspect data in roughly 2% of randomized controlled clinical trials in those journals.

Although the analysis, by John Carlisle, an anesthetist in the United Kingdom, could not determine whether the concerning data were tainted by misconduct or sloppiness, it suggests that editors of the journals have some investigating to do. Of the 98 studies identified by the method, only 16 have already been retracted. [See update at end.]

The types of studies analyzed — randomized controlled clinical trials — are considered the gold standard of medical evidence, and tend to be the basis for drug approvals and changes in clinical practice. Carlisle, according to an editorial by John Loadsman and Tim McCulloch accompanying the new study published today in Anesthesia, Read the rest of this entry »

Written by Ivan Oransky

June 5th, 2017 at 3:45 am

Researchers mistakenly administer three-fold higher dose of anesthesia

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Researchers have retracted a 2016 paper after discovering that they accidentally administered three times the reported dose of anesthesia to rats.

In the Experimental Physiology paper, the authors set out to mathematically map how rats’ blood pressure changes under different conditions, which required the rats to be anesthetized. But their findings were called into question when they found the rats had received a much higher concentration of anesthesia than intended. According to the notice, this higher dose compromised the “objectives of the experiment.”

The corresponding author Karol Ondrias, from the Institute of Molecular Physiology and Genetics at the Slovak Academy of Sciences in Bratislava, told us how the dosing error occurred: Read the rest of this entry »

Editors retract paper about anesthesia procedure after investigation uncovers data issues

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The editors of an anesthesiology journal have retracted a paper about predicting how patients will respond to a procedure, after the results of an investigation cast doubt on the validity and originality of the work.

According to the retraction notice, the editors became concerned about the validity of the data and conducted an investigation, which found irregularities, “including misrepresentation of results.” Because the authors could not provide adequate evidence to assuage these concerns, the editors decided to retract the paper.

The paper — about which facial muscles best predict if a patient is ready to be intubated — had already been flagged on F1000: A few years ago, two anesthesiologists from Florida commented that they found the article “confusing,” and felt that the authors “did not prove their hypothesis.”

Here’s the retraction notice for “Comparison of four facial muscles, orbicularis oculi, corrugator supercilii, masseter or mylohyoid, as best predictor of good conditions for intubation: A randomised blinded trial,” published in the European Journal of Anaesthesiology in 2013 and cited once: Read the rest of this entry »

When you have 94 retractions, what’s two more?

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Attention Joachim Boldt: The 1990s are calling, and they want their papers back.

The Annals of Thoracic Surgery has retracted two papers from the early 1990s on which Boldt was the first author – bringing the retraction tally for the disgraced German anesthesiologist to 96, by our count. Both articles were found to contain manipulated data.

The first paper, from 1990, was titled “Acute Preoperative Plasmapheresis and Established Blood Conservation Techniques,” and was written when Boldt was on the faculty at Justus-Liebig University, in Giessen.

According to the notice:

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Co-author of retraction record-holder likely fabricated his own data, analysis shows

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In 2012, John Carlisle, a British anesthesiologist, demonstrated conclusively using statistics that Yoshitaka Fujii had faked data in many studies. Fujii — as followers of this blog well know — now holds the record for most retractions by an individual author (183).

Carlisle’s work accomplished two things: It put to rest any doubt that problems with Fujii’s work might have resulted from innocent mistakes, and it gave journals a mathematical tool for conducting investigations into potential cases of misconduct.

Now comes the payoff. In a new paper, Carlisle and another anesthesiologist, John Loadsman, take aim at one of Fujii’s frequent co-authors, Yuhji Saitoh of Yachiyo Medical Center and Tokyo Women’s Medical University in Japan. The pair analyzed data from 31 studies Saitoh published between 1993 and 2012 — including one study that was rejected in 2015 — for a total of 32 papers. Of those, 23 did not include Fujii as an author.

Writing in the journal Anaesthesia, where Carlisle published his first study about Fujii, he and Loadsman state that: Read the rest of this entry »

Catching up: Publisher to pull four papers by retraction record holder flagged years ago

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the-laryngoscopeJournals published by Wiley are retracting four papers by Yoshitaka Fujii, the anesthesiology researcher with the most retracted scientific papers.

Retraction Watch readers will be familiar with Fujii’s case: He currently holds the number one spot on our leaderboard with more than 180 retractions, some of which are pending. (That’s nearly twice the number of retractions by the researcher in the #2 spot, Joachim Boldt.) 

Earlier this year, The Breast Journal and The Laryngoscope — both of which are published by Wiley-Blackwell — issued expressions of concern (EOCs) for a total of four papers by Fujii. All four papers were included in a 2012 analysis of 168 of Fujii’s studies by J. B. Carlisle, a consultant anesthetist in the UK, who concluded that the chance of much of Fujii’s data appearing the way it does naturally is

…the chance of selecting one particular atom from all the human bodies on earth.

Now, both journals are retracting the papers. 

A Wiley spokesperson told us: Read the rest of this entry »

Anesthesia journal pulls study lacking patient consent

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Journal of AnesthesiaAn anesthesia journal has retracted a paper after an author admitted that the study did not obtain appropriate consent from patients receiving a neuromuscular block in muscles on the face and hands. 

The first author, Yuhji Saitoh, has the same name as a co-author of Yoshitaka Fujii, the all-time record holder with 183 retractions listed on our leaderboard. Thirty-six of those retracted papers include a co-author with the name of Yuhji Saitoh, but we were unable to confirm this is the same person listed on the newly retracted paper.  

Here’s the retraction notice, issued by the Journal of Anesthesia on August 11: Read the rest of this entry »