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Retraction Watch

Tracking retractions as a window into the scientific process

Archive for the ‘clinical study retractions’ Category

Wrong cell line leads to retraction of kidney cancer study

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plosoneA group of authors in China has retracted their December 2013 paper in PLoS ONE after realizing that they’d been studying the wrong cells.

The paper, “Up-Regulation of pVHL along with Down-Regulation of HIF-1α by NDRG2 Expression Attenuates Proliferation and Invasion in Renal Cancer Cells,” came from Lei Gao, of the Fourth Military Medical University, in Xi’an, and colleagues. It purported to find that:

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Brutal honesty: Author takes to PubPeer to announce retraction — and tells us she’ll lose PhD, professorship

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Eriko Suzuki

Eriko Suzuki

Over the past week, there have been a number of comments on PubPeer — a site of which we’re big fans — about a 2007 paper in Oncogene.

The comments suggested that the figures in the paper had problems. Some bands seemed to be duplicated, and one of the images looked very much like that of another paper.

Then, today, first author Eriko Suzuki left this comment: Read the rest of this entry »

Heart study retracted because it was submitted without permission of most of the authors

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clincardcoverA group of authors in South Korea has lost their 2012 paper in Clinical Cardiology because, well, they weren’t a group after all.

The paper, “Correlation of Electrocardiographic Changes and Myocardial Fibrosis in Patients With Hypertrophic Cardiomyopathy Detected by Cardiac Magnetic Resonance Imaging,” came from corresponding author of Konkuk University School of Medicine in Seoul, and a half-dozen colleagues. At least, that’s what the manuscript said.

But according to the retraction notice, Yang had nothing to do with the paper — nor did five other co-authors. Read the rest of this entry »

Multiple data errors force retraction of paper about preemies

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adcfnA group of neonatal researchers in Caen has lost their 2013 review article in Archives of Disease in Childhood Fetal & Neonatal Edition for a variety of problems with their analysis of the data.

The article was titled “NIDCAP in preterm infants and the neurodevelopmental effect in the first 2 years,” and its first author was Laura Fazilleau of University Hospital Côte de Nacre.

According to the abstract: Read the rest of this entry »

Written by amarcus41

April 16, 2014 at 9:30 am

NIH/Harvard team loses aging study to manipulated data

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agecoverAge has retracted a 2012 article by a group of scientists from the National Institutes of Health and Brigham and Women’s Hospital in Boston after an NIH inquiry turned up evidence of data manipulation in the work.

The article, “Aging decreases rate of docosahexaenoic acid synthesis-secretion from circulating unesterified α-linolenic acid by rat liver,” came from the lab of Stanley Rapoport, chief of the brain physiology and metabolism section of the National Institute on Aging.

As the abstract explained: Read the rest of this entry »

Fraud fells Alzheimer’s “made to order” neurons paper in Cell

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cell414In 2011, a group of researchers at Columbia University reported in Cell that they had been able to convert skin cells from patients with Alzheimer’s disease into functioning neurons — a finding that raised the exciting prospect of “made to order” brain cells for patients with the degenerative disease. As one researcher not involved with the study, led by Asa Abeliovich, put it:

“[This is] simply a remarkable and complete piece of work which will now set a standard for stem cell work in neurological disease. The standard of the characterization of the neuronal cultures is very high,” John Hardy at University College London, U.K., wrote to [Alzforum]. He was not involved in the work but is taking a similar approach in his own lab.

According to the abstract of “Directed Conversion of Alzheimer’s Disease Patient Skin Fibroblasts into Functional Neurons:”

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Harvard-Brigham heart researcher under investigation earns Lancet Expression of Concern

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logo_lancetOn Tuesday, we broke the news of the retraction in Circulation of a paper on cardiac stem cells by a group of researchers being investigated by Harvard Medical School and the Brigham and Women’s Hospital. Today, The Lancet has issued an Expression of Concern about another paper led by Piero Anversa, the last author of the Circulation paper.

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Written by ivanoransky

April 11, 2014 at 6:44 am

Harvard and the Brigham investigating leading heart group for “compromised” data

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circulationcoverCirculation has retracted a 2012 study by a group of Harvard heart specialists over concerns of corrupt data, and the university is investigating. The group was led by Piero Anversa, a leading cardiologist, and Joseph Loscalzo — who will be familiar to readers of Circulation as the editor in chief of that journal. (Anversa’s also on the editorial board).

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Pain study retracted for bogus data is second withdrawal for University of Calgary group

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molpainBack in January 2013, we wrote about the retraction of a paper in Diabetes that the authors had “submitted without knowledge of inherent errors or abnormalities that they recognized in retrospect after submission.”

Now, Molecular Pain has retracted a paper by the same authors, this time for data manipulation. The article, “Comparison of central versus peripheral delivery of pregabalin in neuropathic pain states,” was written by Cory Toth, a clinical neuroscientist at the University of Calgary, in Canada, and colleagues. It has been cited eight times, according to Thomson Scientific’s Web of Knowledge.

Toth said of the Diabetes article at the time:
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Written by amarcus41

April 7, 2014 at 11:00 am

Do you see what I see? Heart imaging journal yanks cardiac study for plagiarism

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intjcardimagThe International Journal of Cardiovascular Imaging has retracted a 2013 paper by a group of researchers from Italy. The reason: plagiarism.

The paper was titled “Diagnostic accuracy of 320-row computed tomography as compared with invasive coronary angiography in unselected, consecutive patients with suspected coronary artery disease,” and it came from scientists in Rome led by Francesco Pelliccia of the Department of Heart and Great Vessels at Sapienza University.

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Written by amarcus41

April 4, 2014 at 11:00 am

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