Archive for the ‘clinical study retractions’ Category
A group of liver researchers from the University of Pittsburgh has earned a pair of corrections in Hepatology for image problems.
The team was led by George K. Michalopoulos, chair of the department of pathology at the University of Pittsburgh Medical Center.
One article, “Excessive hepatomegaly of mice with hepatocyte-targeted elimination of integrin linked kinase following treatment with 1,4-bis [2-(3,5-dichaloropyridyloxy)] benzene,” appeared in January 2011. According to the notice: Read the rest of this entry »
The article was titled “In vitro neutralization of HCV by goat antibodies against peptides encompassing regions downstream of HVR-1 of E2 glycoprotein.” According to the abstract: Read the rest of this entry »
The Office of Research Integrity (ORI) has ruled in a case we’ve been following for nearly two years — and which seems to have been launched after Retraction Watch readers took a careful look at figures from what appeared to be an unrelated case.
Takao Takahashi and Makato Suzuki, both former postdocs at a cancer research center at UT-Southwestern, both “knowingly, intentionally, and recklessly falsified data” in a total of 10 papers, according to the ORI. Takahashi, now at Gifu University in Japan, was responsible for fakery in four papers, while Suzuki, now at Kumamoto University Hospital, also in Japan, falsified data in six.
We reported on the retraction of the four Takahashi papers, and one of the Suzuki papers, in November 2012. At that time, Adi Gazdar, the head of the lab where the researchers worked, told us that
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We brought you this story last week, about a paper on drug resistant staph being retracted for a lab error. Now, we’ve got an update from Rachel Safer, senior editor for medical journals at Oxford University Press, where the paper was published.
Apparently, the researchers “inadvertently relied upon the use of a test system that was not approved for the microorganism studied in their paper,” leading to the retraction, and the corresponding author of the study wasn’t initially all that responsive:
A few weeks after the paper was published on June 9, comments on PubPeer began accumulating. Commenters called out both potentially manipulated and repeated images. The exact timeline is not clear, because Oncogene does not list a date on the retraction notice, but by August 29 the paper had been retracted.
Here’s the notice for “IL-6 secreted by cancer-associated fibroblasts induces tamoxifen resistance in luminal breast cancer,” by researchers at Shanghai Jiaotong University School of Medicine and Ruijin Hospital, both in Shanghai, China, and the University of Michigan: Read the rest of this entry »
What could have been a truly scary study about drug resistant staph infections in hospitals has been retracted due to a lab error.
Researchers at a community hospital in Pittsburgh claimed that the commonly quoted 3% rate of staph that is resistant to ceftriaxone and sensitive to methicillin was drastically understated. However, an “honest error in the interpretation of a key lab test” called the findings into question.
Here’s the notice for “Microstructural Brain Abnormalities of Children of Idiopathic Generalized Epilepsy With Generalized Tonic-Clonic Seizure: A Voxel-Based Diffusional Kurtosis Imaging Study”: Read the rest of this entry »