Retraction Watch

Tracking retractions as a window into the scientific process

Archive for the ‘clinical study retractions’ Category

Researcher who unsuccessfully sued journal to stop retractions earns another expression of concern

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Mario Saad

Mario Saad

A journal has added expressions of concern (EOCs) to four papers about diabetes, including one co-authored by an author who previously sued a different journal when it took a similar action on his papers.

The Journal of Physiology flagged the papers after an investigation “could not rule out the possibility” that they contained duplicated Western blots. Though the three other papers do not include Mario Saad on their author list, he plays a role: The papers include blots duplicated from other papers of Saad’s. And they reveal that Saad may have published those blots multiple times in his own work.

The EOCs all start out with the same statement: Read the rest of this entry »

Study on pregnant women with HIV lied about having ethics approval

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Screen Shot 2016-04-12 at 5.47.50 AMWe recently discovered a relatively old retraction notice — from 2014 — of a study on pregnant women with HIV.

The paper was retracted two years ago when BMC Research Notes discovered the authors falsely claimed they had obtained ethics approval from an institution in Kenya.

The study looked at the effectiveness of an antiretroviral therapy in 50 women who were receiving care at a center in Nairobi, Kenya. But the authors did not have permission from the center to use data from the women, nor the necessary ethics approval from Moi University to carry out the work.

Here’s the retraction note for “Effectiveness of option B highly active antiretroviral therapy (HAART) prevention of mother-to-child transmission (PMTCT) in pregnant HIV women:”

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Written by Shannon Palus

May 6th, 2016 at 11:30 am

Data manipulation flushes paper on gut bacteria

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cell reportsData manipulation in a Cell Reports paper blew the importance of a kind of bacteria out of proportion.

Retracted this month — less than three months after it was published — the paper showed, according to a summary on the cover page:

B. subtilis is a symbiont that resides in the gut of C. elegans and generates nitric oxide that is essential for the host. Xiao et al. demonstrate that nitric oxide promotes defense against pathogenic bacteria by activating p38 MAPK, demonstrating the importance of commensal bacteria in host immunity.

But B. subtilis — a member of the Bacillaceae family — aren’t actually as plentiful as they appeared, explains the retraction notice for “Gut-Colonizing Bacteria Promote C. elegans Innate Immunity by Producing Nitric Oxide:”

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Biologists earn 5th retraction following Swedish investigation

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plos pathA team of biologists have earned a fifth retraction for a paper containing manipulated images, following an investigation by the Swedish government.

Last year, the investigation found that former Uppsala University doctoral student Apiruck Watthanasurorot had manipulated figures in five papers, four of which have already been retracted. Earlier this year, we reported that his supervisor, last author Kenneth Söderhäll, had requested PLOS Pathogens simply correct the fifth paper because independent groups have confirmed the findings. But according to the retraction notice for “Bacteria-Induced Dscam Isoforms of the Crustacean, Pacifastacus leniusculus,” Söderhäll has since agreed to the retraction:

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Cancer paper that doctored image from Science story earns retraction

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lungcancercoverHere’s a joke for all you middle-schoolers out there. How are doctored images like bad pennies? They keep cropping up!

Here’s the latest one we’ve picked up: Lung Cancer has retracted a 2014 paper on the genetics of tumors after concluding the authors cribbed a figure that had appeared in a 2005 feature story in Science.

The paper, “ß-elemene against human lung cancer via up-regulation of P53 protein expression to promote the release of exosome,” drew attention on PubPeer last September from a reader who noticed striking similarities between one of the images the authors used and a figure in the Science piece (subscription required). According to the PubPeer commenter: Read the rest of this entry »

Macchiarini did not obtain necessary ethics approvals, says Swedish Research Council

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lancetSurgeon Paolo Macchiarini did not apply for the necessary ethics approval to perform the pioneering transplants he’s known for, according to the Swedish Research Council.

Chief Legal Counsel Anna Hörnlund, who wrote a letter in this week’s The Lancet, says Macchiarini’s work needed to obtain ethical approval from one of six regional ethical review boards, as required by Swedish law — and neither Macchiarini nor his former employer, Karolinska Institutet, did so:

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Written by Alison McCook

May 2nd, 2016 at 11:30 am

Premature adaptation leads to withdrawal of sexual function paper

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The Journal of Sex & Marital Therapy has retracted a 2012 paper by a pair of authors in Spain who failed to obtain approval to adapt the model of sexual function they used in their study.

The article indicates that the work was based on previous research. But that declaration wasn’t enough to satisfy the creators of the model involved.

As the retraction notice states: Read the rest of this entry »

Team in Japan earns third retraction for misconduct

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JSRA team of researchers has earned its third retraction after an investigation at Oita University in Japan found instances of misconduct in their research.

The most recent notice mentions the investigation, and specifies that the first author, Satoshi Hagiwara, was responsible for the problematic figures in the paper. Hagiwara is also the first author on two retracted papers we reported on last year; one of the earlier retractions also mentions the investigation, but does not assign responsibility to any particular author. All three papers share three authors.

The retraction notice for “Continuous Hemodiafiltration Therapy Ameliorates LPS-Induced Systemic Inflammation in a Rat Model,” published in the Journal of Surgical Research, explains the issues with the paper:

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Paper linking fecal transplants to obesity in rats retracted for faked data

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Diabetes Cover

A paper linking the fecal microbiome to obesity has been retracted after it became clear that one of the co-authors faked some of the data.

The 2014 paper in Diabetes — which found that rats given fecal transplants from obese mice were more likely to become obese themselves if given a particular diet — was pulled after after an institutional investigation found a co-author guilty of falsifying data underlying one figure and fabricating the data of two others.

Co-author Yassine Sakar — formerly based at the French National Institute of Agronomic Research (INRA) in Paris, France — was found responsible for the misconduct. But an official from the institution said that some responsibility must also be shared by the corresponding author Mihai Covosa, who has since resigned from the institution.

Here’s the retraction notice: Read the rest of this entry »

Research assistant fired for using student’s thesis in a paper

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Reviews in Medical Microbiology

A research assistant at King Saud University (KSU) has lost his job after he used material from a student’s thesis without permission or attribution in a paper.

Lakshmana Krishnappa was terminated after a disciplinary committee considered his case last November, the vice dean for postgraduate training and research at KSU told Retraction Watch. In April of last year, Krishnappa retracted a paper published in January 2015 — we think that’s the date; the journal doesn’t make it all that clear — that included plagiarized material, published in Reviews in Medical Microbiology. He recently lost a second unrelated paper for duplication.

Here’s the retraction notice for the Reviews in Medical Microbiology paper, “Acinetobacter baumannii: pathogenecity, virulence factors and their correlation with adherence and invasion:”

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