Archive for the ‘image manipulation’ Category
Jens Christian Schwamborn, a stem cell researcher at the University of Luxembourg, is retracting a 2007 paper on how to grow brain cells.
The paper, “Ubiquitination of the GTPase Rap1B by the ubiquitin ligase Smurf2 is required for the establishment of neuronal polarity,” was published while Schwamborn was at Westfälische Wilhelms‐Universität Münster in Germany. An anonymous critic had sent questions about the study to Germany’s DFG in the middle of last year, and later to Paul Brookes, who posted them on PubMed Commons.
However, questions have been mounting about his research, both on PubPeer (which has critical comments for 15 papers he’s an author on) and in other stem cell labs, who have not been able to reproduce much of Hanna’s work.
We asked Hanna about a PubPeer entry specific to a 2005 paper in Blood. Commenters have accused the authors of figure manipulation and possible data republication. Here’s a figure from that post: Read the rest of this entry »
Alfredo Fusco, a researcher in Italy under criminal investigation, now has a seventh retraction for manipulated images.
Take a look at figure one to the right and see if you can spot all the doubles.
Click here for a more zoomable image.
Here’s the notice for “Denitrosylation of HDAC2 by targeting Nrf2 restores glucocorticosteroid sensitivity in macrophages from COPD patients,” a 2011 paper by researchers at Johns Hopkins and Imperial College: Read the rest of this entry »
Here’s the notice for “Effect of ST3GAL 4 and FUT 7 on sialyl Lewis X synthesis and multidrug resistance in human acute myeloid leukemia,” a paper initially published in June: Read the rest of this entry »
In June, we reported on a retraction in Current Biology that came after a number of PubPeer commenters suggested that the authors had engaged in figure manipulation, memorably comparing watching the published videos to playing the old-school arcade game “Space Invaders.”
Now a second paper from the same team has been retracted from Biology Open after the authors “were unable to repeat the results.” The journal was unable to get in touch with first author Livana Soetedio, whom the University of Illinois at Chicago found had fabricated the data and images in both publications.
A paper by a former postdoc at MD Anderson Cancer Center who “admitted to knowingly and intentionally falsifying” a figure has been retracted.
In August, the Office of Research Integrity announced that it had sanctioned Jun Fu for faking data in a study of the results of a mouse study of NVP-HSP990, a Novartis compound designed to fight brain tumors. Here’s the notice for the study in question, published in Cancer Research:
Read the rest of this entry »
The first retraction, in August of 2013, got a lot of attention for how poorly faked the figures were. At the time, an expression of concern was issued on the paper that has just been retracted.
Today, we exchanged emails with Jeffery Botkin, the research integrity officer at the University of Utah, who ran the investigation into the misconduct. He summarized the report for us below. Read the rest of this entry »
The reason: Image manipulation — which the authors say didn’t materially affect the conclusions of the paper.
The article, “FAK mediates the activation of cardiac fibroblasts induced by mechanical stress through regulation of the mTOR complex,” came from a group led by Ana Paula Dalla Costa, from the State University of Campinas.