Retraction Watch

Tracking retractions as a window into the scientific process

Archive for the ‘image manipulation’ Category

Stem cell researcher retracts neuron paper for “image aberrations”

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embo journalJens Christian Schwamborn, a stem cell researcher at the University of Luxembourg, is retracting a 2007 paper on how to grow brain cells.

The paper, “Ubiquitination of the GTPase Rap1B by the ubiquitin ligase Smurf2 is required for the establishment of neuronal polarity,” was published while Schwamborn was at Westfälische Wilhelms‐Universität Münster in Germany. An anonymous critic had sent questions about the study to Germany’s DFG in the middle of last year, and later to Paul Brookes, who posted them on PubMed Commons.

Those criticisms match the problems listed in the detailed notice: Read the rest of this entry »

Written by Ivan Oransky

December 18th, 2014 at 9:30 am

Stem cell researcher Hanna “working…to correct the unfortunate and inadvertent mistakes” in papers

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jacob

Jacob Hanna

Jacob Hanna of Israel’s Weizmann Institute has been a media darling for years, including as a member of the 2010 Technology Review 30 under 35 for his work with stem cells.

However, questions have been mounting about his research, both on PubPeer (which has critical comments for 15 papers he’s an author on) and in other stem cell labs, who have not been able to reproduce much of Hanna’s work.

We asked Hanna about a PubPeer entry specific to a 2005 paper in BloodCommenters have accused the authors of figure manipulation and possible data republication. Here’s a figure from that post: Read the rest of this entry »

Written by Cat Ferguson

December 17th, 2014 at 1:00 pm

Italian researcher facing criminal charges notches seventh retraction

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proteomicsAlfredo Fusco, a researcher in Italy under criminal investigation, now has a seventh retraction for manipulated images.

Here’s the notice for “Retraction: Identification of new high mobility group A1 associated proteins,” to which not all of the authors agreed: Read the rest of this entry »

Written by Cat Ferguson

December 9th, 2014 at 9:30 am

JCI lymphoma paper retracted after authors can’t find underlying data to explain duplicated bands

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Screen Shot 2014-11-25 at 5.12.55 PMA paper in the Journal of Clinical Investigation has been retracted for manipulated images, including duplicated bands in a Western blot.

Take a look at figure one to the right and see if you can spot all the doubles.

Click here for a more zoomable image.

Here’s the notice: Read the rest of this entry »

Written by Cat Ferguson

December 8th, 2014 at 1:15 pm

COPD paper in JCI retracted following PubPeer critiques

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jciA 2011 paper in the Journal of Clinical Investigation whose PubPeer entry we highlighted in September has been retracted.

Here’s the notice for “Denitrosylation of HDAC2 by targeting Nrf2 restores glucocorticosteroid sensitivity in macrophages from COPD patients,” a 2011 paper by researchers at Johns Hopkins and Imperial College: Read the rest of this entry »

PubPeer strikes again: Leukemia paper retracted for image duplications

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bbaIn July, a PubPeer commenter called out a paper in Biochimica et Biophysica Acta for image duplication; by September, the paper was retracted for the exact reason detailed in the anonymous comment.

Here’s the notice for “Effect of ST3GAL 4 and FUT 7 on sialyl Lewis X synthesis and multidrug resistance in human acute myeloid leukemia,” a paper initially published in June: Read the rest of this entry »

Second retraction appears for arcade game-like image manipulation

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In June, we reported on a retraction in Current Biology that came after a number of PubPeer commenters suggested that the authors had engaged in figure manipulation, memorably comparing watching the published videos to playing the old-school arcade game “Space Invaders.”

Now a second paper from the same team has been retracted from Biology Open after the authors “were unable to repeat the results.” The journal was unable to get in touch with first author Livana Soetedio, whom the University of Illinois at Chicago found had fabricated the data and images in both publications.

Here’s the notice for “Targeting of vasoactive intestinal peptide receptor 2, VPAC2, a secretin family G-protein coupled receptor, to primary cilia”: Read the rest of this entry »

Written by Cat Ferguson

November 19th, 2014 at 11:30 am

Retraction appears for faked study of Novartis anti-cancer compound

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Raymond Sawaya, director of MD Anderson’s brain tumor program, presents Jun Fu with the 2014 Caroline Ross Endowment Fellowship.

Raymond Sawaya, director of MD Anderson’s brain tumor program, presents Jun Fu with the 2014 Caroline Ross Endowment Fellowship.

A paper by a former postdoc at MD Anderson Cancer Center who “admitted to knowingly and intentionally falsifying” a figure has been retracted.

In August, the Office of Research Integrity announced that it had sanctioned Jun Fu for faking data in a study of the results of a mouse study of NVP-HSP990, a Novartis compound designed to fight brain tumors. Here’s the notice for the study in question, published in Cancer Research:
Read the rest of this entry »

University of Utah investigation fingers chemistry grad student for misconduct

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acs nanoA second retraction has been issued in a case of research misconduct at the chemistry department of the University of Utah.

The first retraction, in August of 2013, got a lot of attention for how poorly faked the figures were. At the time, an expression of concern was issued on the paper that has just been retracted.

Today, we exchanged emails with Jeffery Botkin, the research integrity officer at the University of Utah, who ran the investigation into the misconduct. He summarized the report for us below. Read the rest of this entry »

Written by Cat Ferguson

November 6th, 2014 at 3:57 pm

Heart journal pulls paper for image manipulation

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cardresCardiovascular Research has retracted a 2010 paper by a group of prominent cardiology researchers in Brazil.

The reason: Image manipulation — which the authors say didn’t materially affect the conclusions of the paper.

The article, “FAK mediates the activation of cardiac fibroblasts induced by mechanical stress through regulation of the mTOR complex,” came from a group led by Ana Paula Dalla Costa, from the State University of Campinas.

Here’s the abstract of the study, which has been cited 19 times, according to Thomson Scientific’s Web of Knowledge: Read the rest of this entry »