Retraction Watch

Tracking retractions as a window into the scientific process

Archive for the ‘image manipulation’ Category

2014 ORI finding results in retraction of cancer paper with manipulated images

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Mol Can TherA paper flagged in an Office of Research Integrity notice more than one year ago has finally been retracted. According to the notice, the paper includes images manipulated by author H. Rosie Xing, a former University of Chicago cancer researcher.

The main conclusions of the paper are affected by the ORI finding, according to the retraction note from Molecular Cancer Therapeutics. But otherwise, the note contains information that was available in the ORI finding, published in December 2014.

Pharmacologic Inactivation of Kinase Suppressor of Ras1 Sensitizes Epidermal Growth Factor Receptor and Oncogenic Ras-Dependent Tumors to Ionizing Radiation Treatment” has been cited seven times, according to Thomson Scientific’s Web of Knowledge — twice since the ORI finding came out.

The retraction note explains which images were affected by the manipulation:

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Investigation prompts 5th retraction for cancer researcher for “unresolvable concerns”

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3.coverAn investigation at the University of New South Wales in Australia has led to a fifth retraction for a cancer researcher long accused of misconduct, due to “unresolvable concerns” with some images.

As we reported in December, UNSW cleared Levon Khachigian of misconduct, concluding that his previous issues stemmed from “genuine error or honest oversight.” Now, Circulation Research is retracting one of his papers after an investigation commissioned by UNSW was unable to find electronic records for two similar images from a 2009 paper, nor records of the images in original lab books.

Again, the retraction note affirms that this is not a sign of misconduct:

UNSW has not attributed any instance of research misconduct or responsibility for the unavailability of the original data to Professor Khachigian or to any of the authors of the publication.

Here’s the retraction note in full for “Angiotensin II-Inducible Smooth Muscle Cell Apoptosis Involves the Angiotensin II Type 2 Receptor, GATA-6 Activation, and FasL-Fas Engagement:” Read the rest of this entry »

Data irregularities force author to retract three solar cell papers

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no spine minimum. full size. Editor: Jon JEM: Esther RTP: Bryan Nolte TOC image

An engineer has retracted three papers on a method for making nanoscale materials that are useful in solar cells.

The papers, all published in ACS Applied Materials & Interfaces, contain irregularities in data, and one includes images “which have been published elsewhere and identified with different samples,” according to the note.

The first author on all three papers is Khalid Mahmood, who — according to the bio from a talk he gave last year on efficient solar cells — is currently a postdoc at King Abdullah University of Science and Technology in Saudi Arabia. He did the work in the retracted papers while a student at the Korea Advanced Institute of Science and Technology, where, according to the bio, he completed his PhD in two years.

Here’s the retraction note for the first paper (which also contains a typo in the title — “electrospay”)

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EMBO takes back Voinnet’s award, investigates other awardee who just lost a Nature Genetics paper

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Screen Shot 2016-01-28 at 11.41.20 AMEMBO has taken back an award given to beleaguered plant biologist Olivier Voinnet in 2009, and is investigating a recent grantee who had a paper retracted from Nature Genetics yesterday.

The European Molecular Biology Organization (EMBO) “promotes excellence in the life sciences” in Europe, in part by awarding prizes to promising young scientists. Voinnet and Sonia Melo earned their awards by exhibiting potential as young scientists studying genetics — of plants and cancer, respectively — but now EMBO is skeptical of the papers that formed the basis of their applications.

Melo’s Installation Grant from EMBO was announced just last month, and consists of 50,000 Euros annually for three to five years. She is currently based at the University of Porto, in Portugal.

Voinnet’s problems are well-documented on this blog — 21 corrections, seven retractions, and two investigations. Earlier this week, we reported that the Swiss National Science Foundation had cut off Voinnet’s funding, and banned him for three years. Read the rest of this entry »

Paper claiming GMO dangers retracted amid allegations of data manipulation

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FNS2015012717103119A nutrition journal is retracting a paper about potential dangers of eating food containing genetically modified organisms (GMOs) for duplicating a figure, as news stories from Italy are reporting accusations that the last author falsified some of his research.

In the paper, Federico Infascelli, an animal nutrition researcher at the University of Naples, and his colleagues showed modified genes could wind up in the blood and organs of baby goats whose mothers ate GM soybeans. According our Google Translate version of an article by Italian newspaper La Repubblicaan investigation suggests that Infascelli has manipulated images to suggest GMOs are harmful. He could face fines and be suspended from the university.

La Repubblica reports that a committee appointed by the rector of the university, Gaetano Manfredi, found errors in Infascelli’s data that suggested he had manipulated the results to show GMOs were harmful.

One paper by Infascelli has been retracted from Food and Nutrition Science, Gamma-Glutamyl Transferase Activity in Kids Born from Goats Fed Genetically Modified Soybean.” The retraction note says the paper was pulled for duplication:

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Second of 3 retractions appears for biologist, the result of “a substantial number of falsifications”

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Screen Shot 2016-01-13 at 10.19.01 AMA cell biologist who falsifed Western blots has notched a second retraction, with one more expected after a investigation at Nanyang Technological University in Singapore.

First author Sudarsanareddy Lokireddy, now apparently a research fellow at Harvard, did not agree to the retraction, the result of “a substantial number of falsifications.”

In December, we covered the results of the NTU investigation, where Lokireddy used to work. During that investigation, he admitted to falsifying data, Research Integrity Officer Tony Mayer told us. The end result: three retractions.

One of those papers was retracted by Cell Metabolism in December. The second paper, published in Molecular Endocrinology, has been cited 52 times, according to Thomson Scientific’s Web of Knowledge. The retraction note explains which figures were falsified:

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Prostate cancer paper retracted after investigation can’t review original image

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1.coverAn article about how a COX-2 inhibitor (celecoxib) inhibits growth of prostate cancer in rats is being retracted after the authors were unable to provide an investigation committee at New York University with the backup they were asking for.

When the paper was published in 2003, first author Bhagavathi Narayanan worked at the Institute for Cancer Prevention in New York (also known as the American Health Foundation). But when the institute went broke the next year — thanks partly to lavish salaries and offices, as the New York Post reported —  the authors claim they could no longer obtain back up for an image in the paper, once it was questioned years later by NYU, where Narayanan is now based.

Here’s the retraction note, published in Clinical Cancer Research:

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Four retractions follow Swedish government findings of negligence, dishonesty

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242915_1uu_logoA Swedish ethical review board has censured two biologists and their employer, Uppsala University, for events related to “extensive image manipulations” in five papers published between 2010 and 2014. The case has led to criticism from an outside expert — who brought the allegations to Uppsala — over the current system in Sweden for handling such investigations.

Four of the papers have been retracted, and the authors have requested a correction in the fifth.

After an eight-month investigation, in September the government-run Expert Group for Scientific Misconduct at the Central Ethical Review Board in Stockholm, Sweden, concluded that Uppsala professor Kenneth Söderhäll — who has published more than 200 papers — and lecturer Irene Söderhäll acted “negligently” and “dishonestly” by Read the rest of this entry »

Fifth retraction for Wayne State researcher who fudged figures

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Teresita L. Briones

Another retraction has appeared for Teresita Briones, who used to study neuroscience at Wayne State University — the final of five papers flagged by the Office of Research Integrity for containing falsified data.

According to the ORI notice published in May, Briones “intentionally, knowingly, and recklessly engaged in research misconduct by falsifying and/or fabricating data.” This latest paper to be retracted, which looks at the role of specific receptor in chronic inflammation of nervous tissue in rats, has two figures that “were duplicated, reused and falsely relabelled, and claimed to represent different experiments,” according to the retraction note.

The retraction note for “Chronic neuroinflammation and cognitive impairment following transient global cerebral ischemia: role of fractalkine/CX3CR1 signaling,” published in the Journal of Neuroinflammation, specifies the problematic figures:

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Singapore investigation leads to two retractions, two more on the way

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cov150hAuthors have retracted papers from Cell Metabolism and the Journal of Biological Chemistry after an investigation in Singapore found issues, including falsified data. The investigation is ongoing, and two additional retractions, along with two corrections, are on the horizon.

The investigation looked into papers by first authors Sudarsanareddy Lokireddy, now a postdoc at Harvard, and Sandhya Sriram, a postdoc at the Agency for Science, Technology and Research in Singapore. Led by the Nanyang Technological University in Singapore, where some of the work was done, the investigation concluded that there were issues with six papers on which either Sriram or Lokireddy was first author.

All authors but Lokireddy have agreed to retractions or corrections. Ravi Kambadur of NTU, and Mridula Sharma at the National University of Singapore, are the last two authors on all the papers.

According to a notice from the NTU, the “investigation found a number of instances of alterations to data” in three papers on which Lokireddy is first author. One of those was retracted December 1 by Cell Metabolism: Read the rest of this entry »