Archive for the ‘image manipulation’ Category
Brutal honesty: Author takes to PubPeer to announce retraction — and tells us she’ll lose PhD, professorship
The comments suggested that the figures in the paper had problems. Some bands seemed to be duplicated, and one of the images looked very much like that of another paper.
Almost two years ago, we brought you — with the help of Trevor Stokes — the story of a stem cell researcher in Korea whose publication record, and career, unraveled after evidence of image manipulation surfaced in her work.
We’ve reported on four retractions, all in Antioxidants & Redox Signaling, by Soo-Kyung Kang, formerly of Seoul National University resulting from the efforts of a whistleblower. There has been another in Human Gene Therapy: Read the rest of this entry »
The Journal of Biological Chemistry has an illuminating retraction notice — we’re happy to be able to say — about a 2001 article from a group of researchers at the National University of Singapore.
The paper, “Intracellular acidification triggered by mitochondrial-derived hydrogen peroxide is an effector mechanism for drug-induced apoptosis in tumor cells,” was written by Jayshree L. Hirpara, Marie-Véronique Clément and Shazib Pervaiz.
Age has retracted a 2012 article by a group of scientists from the National Institutes of Health and Brigham and Women’s Hospital in Boston after an NIH inquiry turned up evidence of data manipulation in the work.
The article, “Aging decreases rate of docosahexaenoic acid synthesis-secretion from circulating unesterified α-linolenic acid by rat liver,” came from the lab of Stanley Rapoport, chief of the brain physiology and metabolism section of the National Institute on Aging.
Last year, we reported on a Nature correction of a paper for what a McGill University committee had earlier called “intentionally contrived and falsified” figures. It turns out that the correction — like the original paper — left some Nature readers puzzled, so the journal has run a correction of the correction: Read the rest of this entry »
In 2011, a group of researchers at Columbia University reported in Cell that they had been able to convert skin cells from patients with Alzheimer’s disease into functioning neurons — a finding that raised the exciting prospect of “made to order” brain cells for patients with the degenerative disease. As one researcher not involved with the study, led by Asa Abeliovich, put it:
“[This is] simply a remarkable and complete piece of work which will now set a standard for stem cell work in neurological disease. The standard of the characterization of the neuronal cultures is very high,” John Hardy at University College London, U.K., wrote to [Alzforum]. He was not involved in the work but is taking a similar approach in his own lab.
According to the abstract of “Directed Conversion of Alzheimer’s Disease Patient Skin Fibroblasts into Functional Neurons:”
Back in January 2013, we wrote about the retraction of a paper in Diabetes that the authors had “submitted without knowledge of inherent errors or abnormalities that they recognized in retrospect after submission.”
Now, Molecular Pain has retracted a paper by the same authors, this time for data manipulation. The article, “Comparison of central versus peripheral delivery of pregabalin in neuropathic pain states,” was written by Cory Toth, a clinical neuroscientist at the University of Calgary, in Canada, and colleagues. It has been cited eight times, according to Thomson Scientific’s Web of Knowledge.
Toth said of the Diabetes article at the time:
Read the rest of this entry »
The article, “PBOX-15 induces apoptosis and improves the efficacy of oxaliplatin in human colorectal cancer cell lines,” appeared in the European Journal of Pharmacology in August. The first author was Giuseppina Gangemi, of the University of Salerno.
The paper purported to find that:
“I am deeply saddened and disturbed:” Co-author of retracted Nature paper reveals how problems came to light
On Wednesday, we reported on a Nature retraction of a paper whose corresponding author had also had a Cell paper retracted, and had been found to have committed a “violation of academic integrity” by Utrecht University. Today, we present the back story of how those retractions came to be, from another co-author of both papers, Ben Scheres, of Wageningen University: Read the rest of this entry »
There have been a number of developments in the unraveling of two Nature studies out of the RIKEN Institute in Japan and Harvard purporting to show an easy way to create stem cells. There was an interim report of RIKEN’s investigation last Friday, and more details emerged this week.
And today, the Japan Times reported that last week, a correction of a 2011 paper by many of the same authors appeared in Tissue Engineering Part A. Here’s the correction notice, dated March 13: Read the rest of this entry »