Retraction Watch

Tracking retractions as a window into the scientific process

Archive for the ‘pharmaceutical biology’ Category

Error scuppers paper on treatment for liver fibrosis

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pharmbioPharmaceutical Biology has retracted a 2012 paper by a group of liver researchers from China after the discovery of an error that evidently invalidated the results in the paper.

The article, “Antifibrotic effects of protocatechuic aldehyde on experimental liver fibrosis,” purported to show that

protocatechuic aldehyde, the major degradation of phenolic acids … has potentially conferring antifibrogenic effects.

In other words, the compound appears to prevent the formation of liver fibroids.
But it doesn’t — at least, not according to the study — as the retraction notice explains: Read the rest of this entry »

South Korean plant compound researcher faked email addresses so he could review his own studies

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Hyung-In Moon

Scientists frustrated by the so-called “third reviewer” — the one always asking for additional experiments before recommending acceptance — might be forgiven for having fantasies of being able to review their own papers.

But one Korean scientist, Hyung-In Moon, managed to do just that, through what must have seemed like clever subterfuge at the time. And he got away with it for a while — until he didn’t, as witnessed by this retraction notice for “Larvicidal activity of 4-hydroxycoumarin derivatives against Aedes aegypti,” published in Pharmaceutical Biology, an Informa Healthcare title: Read the rest of this entry »