Retraction Watch

Tracking retractions as a window into the scientific process

Archive for the ‘sam w. lee’ Category

Paper by Harvard cancer biologist flagged over “credible concerns”

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A cancer biologist at Harvard who’s issued multiple editorial notices in recent years has received an expression of concern about a 2011 paper, citing “credible concerns” with the data and conclusions.

The publisher does not detail the nature of the issues in the notice.

In the past few years, last author Sam W. Lee lost a Molecular Cell paper in 2013 due to figure duplication and a Journal of Biological Chemistry paper in 2015, citing “manipulated” data in a figure.

Lee also issued two mega-corrections in 2011 in Nature and Current Biology, which also cited figure duplication. Interestingly, both papers were corrected for a second time — the 2006 Current Biology paper in 2016, over figure-related errors, and the 2011 Nature paper in 2015, over concerns the animals used may have experienced excess suffering (prompting an editorial from the journal).

The latest notice, issued by the Journal of Biological Chemistry, doesn’t provide much information for the basis of its expression of concern over Lee’s 2011 paper: Read the rest of this entry »

Retraction appears for Harvard scientist who had two mega-corrections last year

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molecular cellSam Lee, a Harvard biologist who had two mega-corrections published last year, has retracted a paper in Molecular Cell because some of the figures were “inappropriately assembled.”

Here’s the notice for “GAMT, a p53-Inducible Modulator of Apoptosis, Is Critical for the Adaptive Response to Nutrient Stress:” Read the rest of this entry »

Written by Ivan Oransky

August 23rd, 2013 at 8:30 am

Image correction in Current Biology for Harvard’s Sam Lee

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The work of Sam W. Lee, a cancer biologist at Harvard and Massachusetts General Hospital, has come under fire at Science Fraud lately over concerns about the possible reuse of images in his group’s published studies.

Turns out there’s some there, there after all. The journal Current Biology has issued a pretty thorny correction for one of Lee’s 2006 articles, “RhoE Is a Pro-Survival p53 Target Gene that Inhibits ROCK I-Mediated Apoptosis in Response to Genotoxic Stress,” citing multiple issues with its figures: Read the rest of this entry »