About these ads

Retraction Watch

Tracking retractions as a window into the scientific process

JCI retracts 10-year-old cancer study because figures were “intentionally mislabeled”

with 5 comments

jci june 14The Journal of Clinical Investigation is retracting a 2004 paper by a cancer researchers from Italy because of “evident misrepresentation of data and image duplication.”

Here’s the notice for “The IL-12Rβ2 gene functions as a tumor suppressor in human B cell malignancies:”

It has come to our attention that multiple gel images in Figure 1A were inappropriately duplicated from a previous publication (Airoldi I. et al. Expression and function of IL-12 and IL-18 receptors on human tonsillar B cells. J Immunol. 2000;165(12):6880–6888) in violation of JCI editorial policy. The experimental results presented in Figure 1A were intentionally mislabeled as representing total tonsil B lymphocytes and naive, GC, and memory B cells from the same tonsil, in contrast with the sample labeling in the previous publication. The JCI editorial board is retracting this article due to the evident misrepresentation of data and image duplication. No issues have been raised in regard to any of the other data in this manuscript.

The paper has been cited 48 times, according to Thomson Scientific’s Web of Knowledge.

Pseudonymous whistleblower Clare Francis contacted the journal about the issues in the paper in November of last year.

About these ads

5 Responses

Subscribe to comments with RSS.

  1. The senior author of the paper has these entries at Pubpeer:-

    J Clin Invest. 2004;113(11):1651–1659. The topic of this post.
    https://pubpeer.com/publications/15173892

    Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):3996-4001.
    https://pubpeer.com/publications/17360466

    PLoS One. 2009 Jul 1;4(7):e6119.
    https://pubpeer.com/publications/19582164

    Cancer Res. 2006 Apr 15;66(8):3978-80.
    https://pubpeer.com/publications/16618714

    Br J Cancer. 2004 Jun 1;90(11):2210-8.
    https://pubpeer.com/publications/15150552

    Br J Cancer. 2003 May 19;88(10):1527-36.
    https://pubpeer.com/publications/12771917

    Neoplasia. 2004 Sep-Oct;6(5):558-68.
    https://pubpeer.com/publications/15548365

    david hardman

    June 6, 2014 at 10:14 am

  2. Wonderful, JCI is indeed the scientific journal to praise read, cyte and buy!!!! I wish other respecful journal such as Science, The large Nature family J., Cell, … had the same ability to listen and act! So much time and money wasted on what cannot be called “science”!!! It is like christie’s was auctioning at the same starting price a photograph made by Robert Mapplethorpe and one of my selfies!! How long will it take to Christie’s to get out of business? Anyhow Many Thanks to Clare Francis and to JCI

    Paul

    June 8, 2014 at 3:42 am


We welcome comments. Please read our comments policy at http://retractionwatch.wordpress.com/the-retraction-watch-faq/ and leave your comment below.

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

Follow

Get every new post delivered to your Inbox.

Join 33,801 other followers

%d bloggers like this: