According to the notice for the paper, which has been cited 8 times, according to Thomson Scientific’s Web of Knowledge:
Retraction for “GCK is essential to systemic inflammation and pattern recognition receptor signaling to JNK and p38,” by Jian Zhong, L. Cristina Gavrilescu, Árpád Molnár, Lauren Murray, Stephen Garafalo, John H. Kehrl, Amy R. Simon, Richard A. Van Etten, and John M. Kyriakis, which appeared in issue 11, March 17, 2009, of Proc Natl Acad Sci USA (106:4372–4377; first published February 25, 2009; 10.1073/pnas.0812642106).
The undersigned authors wish to note the following: “Upon rederivation of the gck-/- mouse line, we have been unable to reproduce the data showing that disruption of gck impairs PAMP activation of JNK and p38. We also cannot reproduce the finding that administration of PAMPs leads to the signal-dependent stabilization of endognous GCK. Inasmuch as these signal transduction findings supported a central conclusion of the above article, we wish to retract this article in its entirety.”
But not all of the authors were on that list of the undersigned. The first author, Jian Zhong, didn’t sign. We tried reaching him to ask why, but while his Tufts profile page is still active, his Tufts email bounced.
So what made the authors rederive their cell lines? We’ve asked senior author John Kyriakis for more details, but he referred us to the Tufts media affairs office. They tell us:
Dr. Zhong left our institution for another opportunity several years ago, and he didn’t respond to our attempts to reach him regarding the retraction.
Hat tip: Vladimir Svetlov