Cleveland Clinic heart researchers earn two expressions of concern

Cleveland Clinic, via Wikimedia

A team of heart researchers at Cleveland Clinic in Ohio has received expressions of concern for two papers in the Journal of Biological Chemistry, which says the images in the articles appear suspect. 

The papers, both of which appeared in 2004, come from the lab of Subha Sen, a highly-funded scientist who has received millions in NIH grants over the past decade. Sen’s work also has drawn scrutiny on PubPeer, with comments cropping up on the site roughly three years ago for many of her papers

In 2016, Sen’s group retracted a 2009 article in JBC titled “A unique microRNA profile in end-stage heart failure indicates alterations in specific cardiovascular signaling networks.” According to the notice: 

Continue reading Cleveland Clinic heart researchers earn two expressions of concern

Keeping coronavirus numbers straight: JAMA sounds an alarm

via CDC

As Retraction Watch readers know, reporting on the same data more than once — without notifying editors and readers — is bad for the scientific record and can lead to a retraction. Apparently, in the rush to publish findings about the coronavirus pandemic, some researchers are doing just that.

According to an editorial in JAMA today by editor in chief Howard Bauchner and two deputy editors, Robert Golub and Jody Zylke:

Continue reading Keeping coronavirus numbers straight: JAMA sounds an alarm

“Statins May Cut Glaucoma Risk,” said a New York Times headline. But is that true?

via Flickr

Last year, JAMA Ophthalmology published a study that claimed to find a link between using cholesterol-lowering drugs known as statins and a reduced risk of glaucoma. In a New York Times story on the paper, lead author

Jae H. Kang, an assistant professor of medicine at Brigham and Women’s Hospital in Boston, suggested that statins reduce pressure in the eye, help maintain good blood flow and may help protect the optic nerve.

But Kang came to realize, while reviewing the results for another study, that her research had a major error, as she writes in a letter accompanying the retraction and replacement of the study. Kang tells Retraction Watch:

Continue reading “Statins May Cut Glaucoma Risk,” said a New York Times headline. But is that true?

Weekend reads: Museum director sues after suspension; Nobelist ’embroiled in research scandal;’ spider biologist lawyers up after retractions

Before we present this week’s Weekend Reads, a question: Do you enjoy our weekly roundup? If so, we could really use your help. Would you consider a tax-deductible donation to support Weekend Reads, and our daily work? Thanks in advance.

The week at Retraction Watch featured:

Here’s what was happening elsewhere:

Continue reading Weekend reads: Museum director sues after suspension; Nobelist ’embroiled in research scandal;’ spider biologist lawyers up after retractions

A ‘Cat Tale’: A story of how flawed science formed the basis of policy

On the surface, it would seem like a good thing when science undergirds policy decisions. But what if that science is deeply flawed? Craig Pittman, an award-winning journalist at the Tampa Bay Times and author of 4 books, writes that his new book Cat Tale: The Wild, Weird Battle to Save the Florida Panther is “a tale of raw courage, of scientific skulduggery and political shenanigans, of big-money interests versus what’s right for everyone.” In this excerpt, Pittman explains what happened — and what didn’t — after a group of scientists known as the Science Review Team (SRT) found serious problems in research used to support regulatory policies involving panthers.

In 2003, the SRT released a report containing its verdict. As you might guess, it ripped apart Maehr’s work, piece by piece, and yes, they called him out by name. They didn’t label him a fraud, but they made it clear that Dr. Panther had done some pretty shady things.

Because they were scientists, they didn’t scream out their find­ings in impassioned prose. They were cool and calm—but there was no mistaking what they were saying.

Continue reading A ‘Cat Tale’: A story of how flawed science formed the basis of policy

‘I shot at my own foot with my own gun’: Journal rebuffs attempt at un-retraction

via Flickr

An Elsevier journal has denied the efforts of a group of researchers — well, most of them, anyway — to reverse a retraction after having agreed to the move in the first place.

The dispute centers on a 2018 paper in Preventive Medicine Reports titled  “Association between low-testosterone and kidney stones in US men: The national health and nutrition examination survey 2011–2012” — which, as the title implies, found that:

Continue reading ‘I shot at my own foot with my own gun’: Journal rebuffs attempt at un-retraction

‘Harming‌ ‌the‌ ‌scientific‌ ‌process‌:’ An attempt to correct the sports science literature, part 3

Matthew Tenan

Why is it so difficult to correct the scientific record in sports science? In the first installment in this series of guest posts, Matthew Tenan, a data scientist with a PhD in neuroscience, began the story of how he and some colleagues came to scrutinize a paper. In the second, he explained what happened next. In today’s final installment, he reflects on the editors’ response and what he thinks it means for his field.

In‌ ‌refusing‌ ‌to‌ ‌retract‌ ‌the‌ ‌Dankel‌ ‌and‌ ‌Loenneke‌ ‌manuscript‌ ‌we‌ ‌showed‌ ‌to‌ ‌be‌ ‌mathematically‌ ‌flawed,‌ ‌the‌ ‌editors‌ referred to “feedback‌ ‌from‌ ‌someone‌ ‌with‌ ‌greater‌ ‌expertise”‌ and ‌included‌ ‌the‌ ‌following:‌ ‌

Continue reading ‘Harming‌ ‌the‌ ‌scientific‌ ‌process‌:’ An attempt to correct the sports science literature, part 3

‘A flawed decision:’ What happened when sports scientists tried to correct the scientific record, part 2

Matthew Tenan

Why is it so difficult to correct the scientific record in sports science? In the first installment in this series of guest posts, Matthew Tenan, a data scientist with a PhD in neuroscience, began the story of how he and some colleagues came to scrutinize a paper. In this post, he explains what happened next.

The‌ ‌journal‌ ‌Sports‌ ‌Medicine‌ ‌is‌ ‌widely‌ ‌considered‌ ‌one‌ ‌of‌ ‌the‌ ‌top‌ ‌journals‌ ‌–‌ ‌if‌ ‌not‌ ‌the‌ ‌top‌ ‌journal‌ ‌–‌ ‌in‌ ‌the‌ ‌fields‌ ‌of‌ ‌sport‌ ‌science,‌ ‌exercise‌ ‌science‌ ‌and‌ ‌physical‌ ‌education.‌  ‌This‌ ‌journal‌ ‌is‌ ‌managed‌ ‌by‌ ‌two‌ ‌professional‌ ‌editors‌ ‌who‌ ‌do‌ ‌not‌ ‌hold‌ ‌PhDs‌ ‌in‌ ‌the‌ ‌journal’s‌ ‌subject‌ ‌area‌ ‌but‌ ‌are‌ ‌generally‌ ‌versed‌ ‌in‌ ‌the‌ ‌topic‌ ‌and‌ ‌have‌ ‌the‌ ‌goal‌ ‌of‌ ‌managing‌ ‌a‌ ‌successful‌ ‌journal‌ ‌for‌ ‌SpringerNature.‌ ‌

The‌ ‌manuscript‌ ‌by‌ ‌Dankel‌ ‌and‌ ‌Loenneke‌ ‌was‌ ‌reviewed‌ ‌by‌ ‌three‌ ‌reviewers.‌  ‌I‌ ‌know‌ ‌this‌ ‌because‌ ‌I‌ ‌was‌ ‌one‌ ‌of‌ ‌the‌ ‌reviewers‌ ‌and,‌ ‌as‌ ‌noted‌ ‌in‌ ‌the‌ ‌first‌ ‌post‌ ‌in‌ ‌this‌ ‌series,‌ ‌I‌ ‌strongly‌ ‌advised‌ ‌against‌ ‌its‌ ‌publication.‌ ‌Greg‌ ‌Atkinson,‌ ‌a‌ ‌practicing‌ ‌scientist‌ ‌in‌ ‌the‌ ‌area‌ ‌of‌ ‌health‌ sciences,‌ ‌has‌ ‌publicly‌ ‌stated‌, in a private Facebook group, that he‌ ‌was‌ ‌one‌ ‌of‌ ‌the‌ ‌reviewers‌ ‌who‌ ‌recommended‌ ‌the‌ ‌paper‌ be‌ ‌published.‌ ‌Both‌ ‌myself,‌ ‌Atkinson,‌ ‌and‌ ‌the‌ ‌senior‌ ‌author‌ ‌on‌ ‌the‌ ‌manuscript,‌ ‌Loenneke,‌ ‌sit‌ ‌on‌ the‌ ‌editorial‌ ‌board‌ ‌of‌ ‌the‌ ‌journal‌ ‌Sports‌ ‌Medicine.‌ ‌And‌ ‌while‌ ‌the‌ ‌paper‌ ‌published‌ ‌in‌ ‌the‌ ‌journal‌ ‌by‌ ‌Dankel‌ ‌and‌ ‌Loenneke‌ ‌proposes‌ ‌a‌ ‌novel‌ ‌statistical‌ ‌method,‌ ‌neither‌ ‌of‌ ‌the‌ ‌two‌ ‌authors‌ ‌on‌ ‌the‌ ‌manuscript,‌ ‌myself,‌ ‌nor‌ ‌Atkinson,‌ ‌have‌ ‌PhDs‌ ‌in‌ ‌statistics.‌ ‌The‌ ‌published‌ ‌paper‌ ‌does‌ ‌not‌ ‌cite‌ ‌a‌ ‌single‌ ‌statistics‌ ‌journal‌ ‌in‌ ‌the‌ ‌course‌ ‌of‌ ‌reporting‌ ‌their‌ ‌“novel‌ ‌method.”‌

‌What‌ ‌could‌ ‌go‌ ‌wrong,‌ ‌right?‌ ‌

Continue reading ‘A flawed decision:’ What happened when sports scientists tried to correct the scientific record, part 2

Why — even after reforms for an episode involving bad statistics — is it so difficult to correct the sports medicine literature? Part 1

Matthew Tenan

Two years ago, following heated debate, a sports science journal banned a statistical method from its pages, and a different journal — which had published a defense of that method earlier — decided to boost its statistical chops. But as Matthew Tenan, a data scientist with a PhD in neuroscience relates in this three-part series, that doesn’t seem to have made it any easier to correct the scientific record. Here’s part one.

In‌ ‌July‌ ‌2019,‌ ‌my‌ ‌colleague‌ ‌‌Andrew‌ ‌Vigotsky‌‌ ‌contacted‌ ‌me.‌ ‌He‌ ‌was‌ ‌curious,‌ ‌he‌ ‌said,‌ ‌whether‌ ‌a‌ paper‌ ‌published‌ ‌in‌ ‌Sports‌ ‌Medicine‌ ‌had‌ ‌undergone‌ ‌statistical‌ ‌review ‌ ‌because‌ ‌he‌ ‌was‌ concerned‌ ‌about‌ ‌some‌ ‌of‌ ‌its‌ ‌claims.‌ ‌The‌ ‌link‌ ‌he‌ ‌sent‌ ‌me‌ ‌was‌ ‌to‌ ‌“‌A‌ ‌Method‌ ‌to‌ ‌Stop‌ ‌Analyzing‌ Random‌ ‌Error‌ ‌and‌ ‌Start‌ ‌Analyzing‌ ‌Differential‌ ‌Responders‌ ‌to‌ ‌Exercise‌,”‌ ‌a‌ ‌paper‌ ‌published‌ ‌on‌ June‌ ‌28,‌ ‌2019‌ ‌by‌ ‌‌Scott‌ ‌Dankel‌‌ ‌and‌ ‌‌Jeremy‌ ‌Loenneke‌.‌

As‌ ‌it‌ ‌happened,‌ ‌I‌ ‌knew‌ ‌that‌ ‌paper,‌ ‌and‌ ‌I‌ ‌had‌ ‌also‌ ‌expressed‌ ‌concerns‌ ‌about‌ ‌it‌ ‌–‌ ‌when‌ ‌I reviewed‌ ‌it‌ ‌before‌ ‌publication‌ ‌as‌ ‌one‌ ‌of‌ ‌the‌ ‌members‌ ‌of‌ ‌the‌ ‌journal’s‌ ‌editorial‌ ‌board.‌ ‌Indeed,‌ ‌I was‌ ‌brought‌ ‌on‌ ‌to‌ ‌the‌ ‌editorial‌ ‌board‌ ‌of‌ ‌‌Sports‌ ‌Medicine‌‌ ‌because‌ ‌the‌ ‌journal‌ ‌had‌ ‌recently‌ received‌ ‌a‌ ‌lot‌ ‌of‌ ‌bad‌ ‌press‌ ‌for‌ ‌publishing‌ ‌a‌ ‌paper‌ ‌about‌ ‌another‌ ‌“novel‌ ‌statistical‌ ‌method”‌ ‌with‌ significant‌ ‌issues and I had been a vocal critic of the sports medicine and sport science‌ field developing their own statistical methods that are not used outside of the field and validated by the wider statistics community.‌ ‌

Continue reading Why — even after reforms for an episode involving bad statistics — is it so difficult to correct the sports medicine literature? Part 1

Weekend reads: A whistleblower is fired; problems in heart research; doing the right thing in science

Before we present this week’s Weekend Reads, a question: Do you enjoy our weekly roundup? If so, we could really use your help. Would you consider a tax-deductible donation to support Weekend Reads, and our daily work? Thanks in advance.

The week at Retraction Watch featured:

Here’s what was happening elsewhere:

Continue reading Weekend reads: A whistleblower is fired; problems in heart research; doing the right thing in science