University requests 20 retractions of cancer papers following probe

Santosh Katiyar

A university and medical center have requested a batch of retractions following an investigation that found 20 papers by a cancer researcher contained manipulated images.

The request, from University of Alabama, Birmingham (UAB) and Birmingham VA Medical Center, focuses on papers by Santosh Katiyar, who explored alternative approaches to treating skin cancer in animal models.

For more, see our story out today in The Scientist.

Continue reading University requests 20 retractions of cancer papers following probe

A cancer researcher said she collected blood from 98 people. It was all her own.

A researcher collected her own blood and forged the labels so it would appear to be samples from nearly 100 people, according to a new finding of research misconduct released today by the U.S. Office of Research Integrity (ORI).

The former researcher at the University of Texas MD Anderson Cancer Center swapped her own blood samples for those taken from 98 human subjects. The misconduct affects two grant progress reports and two papers; one paper has already been retracted, and the former “research interviewer” — Maria Cristina Miron Elqutub — has agreed to correct or retract the other.

Adel El-Naggar, a co-author on both of the papers also based at the University of Texas MD Anderson Cancer Center, told Retraction Watch:

Continue reading A cancer researcher said she collected blood from 98 people. It was all her own.

A former employee admitted to scientific misconduct. His new institution likely doesn’t know. What should you do?

A few years ago, Richard Miller of the University of Michigan had a serious dilemma: He discovered a former researcher in his lab was doing research somewhere else. Normally, that would be fine — except this research had admitted to committing misconduct in Miller’s lab.

Should he tell the researcher’s new employer? Continue reading A former employee admitted to scientific misconduct. His new institution likely doesn’t know. What should you do?

Controversial Australian science journalist admits to duplication in her PhD thesis

Maryanne Demasi

A prominent (yet controversial) journalist in Australia has admitted to duplicating three images that were part of her PhD thesis — a practice outside experts agreed was acceptable, if not ideal, at the time, according to a report released today.

As part of an inquiry, the University of Adelaide convened an expert panel to investigate 17 allegations of duplication and/or manipulation in Maryanne Demasi’s 2004 thesis. Duplication is a common reason for retractions, such as when researchers use the same image to depict the results of different experiments.

After earning her PhD in rheumatology, Demasi became a journalist who got headlines for more than just her reporting. In 2013, she produced a controversial series about cholesterol and fat (which suggested they have been unfairly villainized, and which cast doubt on cholesterol-lowering drugs known as statins). A few years later, Demasi was fired from the science program Catalyst, after it aired an episode alleging wi-fi could cause brain tumors.

Regarding the allegations of misconduct in Demasi’s thesis, the originals of the images in question were long gone, so in 14 instances, an expert concluded it was not possible to conclude whether or not duplication had occurred. But in the remaining three instances, Demasi admitted she had “duplicated or probably duplicated” the images:

Continue reading Controversial Australian science journalist admits to duplication in her PhD thesis

Prominent researcher dismissed following misconduct probe

Yoshinori Watanabe

The University of Tokyo has fired a high-profile cell biologist after a probe determined his group had falsified data.

According to a news release issued today (in Japanese), the university has issued a “disciplinary dismissal” of Yoshinori Watanabe (according to our Google translate of the notice).

In 2016, the institution began an investigation of seven papers from Watanabe’s lab after receiving anonymous allegations. In August 2017, the university announced the result: Five papers contained falsified or fabricated images. One — a 2015 Science paper — has already been retracted.

According to Clarivate Analytics’ Web of Science, Watanabe has published more than 100 papers, which have been cumulatively cited thousands of times.

Last year, regarding the Science retraction, Watanabe told us:

Continue reading Prominent researcher dismissed following misconduct probe

Researcher loses battle with Cell over wording of retraction notice

For months, a researcher has wrestled with a journal over the wording of an upcoming retraction notice. It appears that she has lost.

Earlier this week, Cell retracted the paper, despite the protests of first author Shalon Babbitt Ledbetter. When Ledbetter learned the journal was planning to retract the biochemistry paper over image manipulations, but wouldn’t name the culprit in the notice, she shared her concerns on PubPeer. Although a 2015 letter sent to Cell from Saint Louis University identified last author Dorota Skowyra as responsible for multiple manipulations, the journal wasn’t planning to say Skowyra was responsible in the retraction notice. Which would leave all other authors — particularly Ledbetter — under a cloud of suspicion.

Now, Cell Press has finally retracted the paper, along with another paper in Molecular Cell that lists Skowyra as corresponding author. Both notices describe image manipulations that were investigated by Saint Louis University (SLU). Neither identifies who is responsible.

Continue reading Researcher loses battle with Cell over wording of retraction notice

Child psychiatrist’s research was suspended “indefinitely” following probe

Mani Pavuluri

The University of Illinois at Chicago (UIC) permanently suspended all research activities for a child psychiatrist years ago following an inquiry into her work, Retraction Watch has learned.

In 2015, a UIC spokesperson told us the university had suspended Mani Pavuluri’s clinical research in 2013, after a child in one of her studies had been hospitalized for exhibiting an increase in irritability and aggression. This prompted the university to launch a misconduct probe, and send letters to approximately 350 families of children participating in the research, notifying them of what happened. Now, a spokesperson has informed us that after the institution concluded its probe, it suspended her research “indefinitely.”

Continue reading Child psychiatrist’s research was suspended “indefinitely” following probe

Caught Our Notice: Researcher who sued PubPeer commenter up to 21 retractions

Titles: 1) Notch-1 induces Epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells

2) Sensitization of squamous cell carcinoma to cisplatin induced killing by natural agents

What Caught Our Attention: Regular readers will be familiar with the saga involving Fazlul Sarkar and PubPeer: In 2014, Sarkar sued anonymous commenters on the site, claiming defamation (and that damaging comments may have cost him a new job). Although Sarkar won an initial ruling, it was overturned by an appeals court. In the midst of that, the ACLU (which represented PubPeer in the case) released a copy of a misconduct investigation report compiled by Sarkar’s institution, Wayne State University, which concluded that he had committed enough misconduct to warrant retracting 40 papers. The two latest notices, both of which cite Wayne State’s investigation, bring Sarkar’s total to 21.   Continue reading Caught Our Notice: Researcher who sued PubPeer commenter up to 21 retractions

Paper used to support WHO guidelines on preventing infections “has no scientific validity”

A surgery journal retracted a 2014 paper last month after discovering that the study has “no scientific validity.”

Mario Schietroma and his coauthors, based at the University of LAquila in Italy, reported that giving patients high concentrations of oxygen during and after colorectal surgery significantly reduced their risk of infections. Although the authors reported significant p-values, the retraction notice states that, “upon recalculation, no p-values were close to significant.” The University of LAquila told Retraction Watch it is investigating, but did not provide details. Continue reading Paper used to support WHO guidelines on preventing infections “has no scientific validity”

Caught Our Notice: Former rising star loses fourth paper

Title: Haemophilus influenzae responds to glucocorticoids used in asthma therapy by modulation of biofilm formation and antibiotic resistance

What Caught Our Attention: This is the fourth retraction for Robert Ryan, formerly a high-profile researcher studying infections that can be deadly in people with lung diseases such as cystic fibrosis. In 2016, the University of Dundee in Scotland determined that Ryan had committed research misconduct, including misrepresenting clinical data and duplicating images in a dozen different publications. (Ryan tried to appeal the decision, then resigned.) The latest retraction cites a few problems with the paper, including uncertainty about the provenance of some data.

According to the notice, the second-to-last author, George A. O’Toole at Dartmouth, disagrees with the text of the notice, not the decision to retract. We contacted O’Toole, who declined to comment.

We received a statement from Ryan about the retraction:

Continue reading Caught Our Notice: Former rising star loses fourth paper