Journals acknowledge that a critical “reader” has a name: Elisabeth Bik

Elisabeth Bik

Followers of this blog know that “a reader” seems to be the force behind a huge number of retractions – and that, despite the apparent unwillingness of journals to name them, they are real people. One of the more prolific “readers” is Elisabeth Bik, the data sleuth whose efforts to identify problematic images has led to the removal of hundreds of dodgy papers.

Journals now seem more willing to give credit where it’s due, by identifying Bik – who has faced threats for her efforts – in their notices.  

A few recent examples: Biomedicine & Pharmacotherapy, an Elsevier title, has name-checked Bik in a dozen retractions of papers dating back to 2017. 

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University of Glasgow ‘in discussions to retract’ seven papers, confirming Retraction Watch reporting

Miles Houslay

The University of Glasgow is “in discussions to retract” seven papers by a pharmacology researcher who worked there for more than 25 years, after it learned of allegations on PubPeer by pseudonymous whistleblower Clare Francis.

The development confirms reporting by Retraction Watch earlier this month. In that post, we wrote: 

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Journal mulls expression of concern for Cassava Sciences paper

A journal is considering issuing an expression of concern for a 2005 paper by authors tied to a company that’s now under investigation for fraud, Retraction Watch has learned. 

[See an update on this post (bottom).]

The article, “Ultra-low-dose naloxone suppresses opioid tolerance, dependence and associated changes in mu opioid receptor–G protein coupling and Gβγ signaling,” was written by a group linked to Pain Therapeutics, Inc., which in 2019 changed its name to Cassava Sciences.

Last week, the Wall Street Journal reported that the U.S. Securities and Exchange Commission and the National Institutes of Health were investigating claims that the company manipulated data for simulfilam, its experimental drug for Alzheimer’s disease. 

As we reported in August, a law firm submitted a “citizen’s petition” to the FDA citing: 

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Exclusive: Urology researcher demoted after misconduct investigation — then becomes chair at another school

Hari Koul

A urology researcher at Louisiana State University lost his post as department chair after a misconduct investigation, Retraction Watch has learned. But he eventually moved on to be department chair at a different LSU campus — where he remains today.

In June, we reported that the work of urology researcher Hari Koul had been investigated by his former employer, the University of Colorado, following a recommendation by LSU. But between the time the misconduct investigation concluded in 2014 and the publication of our story, only three of nine papers by Koul that Colorado recommended for corrections or retractions had been amended in any way. More of those publications have been retracted following our story, the reporting of which was how some editors learned of the issues.

Now, via a public records request, we’ve gained access to the inquiry at LSU which led to the investigation at CU Denver and includes notes from interviews with Koul and his postdoc. The Denver investigation didn’t find Koul guilty of misconduct, but it found many errors in his published work, leading LSU’s Health Science Center in Shreveport to demote him in 2016. After several years of apparently unrelated legal battles with LSU’s Health Science Center in Shreveport, Koul moved to a different LSU institution, LSU Health Sciences Center in New Orleans, last year.

Continue reading Exclusive: Urology researcher demoted after misconduct investigation — then becomes chair at another school

“Fabulous document”, “very helpful guidance”: Sleuths react to recommendations for handling image integrity issues

Retraction Watch readers are likely familiar with the varied — and often unsatisfying — responses of journals to scientific sleuthing that uncovers potential problems with published images. Some editors take the issues seriously, even hiring staff to respond to allegations and vet manuscripts before publication. Some, however, take years to handle the allegations, or ignore them altogether.

Recently, STM’s Standards and Technology Committee (STEC) appointed a working group to look at these issues At  a webinar last week, the group — including members from the American Chemical Society, Elsevier, Springer Nature, Taylor & Francis, Wiley, and other publishers — released a draft of their recommendations, which:

Continue reading “Fabulous document”, “very helpful guidance”: Sleuths react to recommendations for handling image integrity issues

Highly cited paper marks 14th retraction for Chinese Academy of Sciences researcher

A chemistry journal has retracted a 2014 paper by a group from China after the first author on the article copped to having Photoshopped a figure — marking the second retraction for members of the group in less than a week and the 14th for one of the authors

The paper, “Polymer nanodots of graphitic carbon nitride as effective fluorescent probes for the detection of Fe3+ and Cu2+ ions,” appeared in Nanoscale and was written by a group with ties to Soochow University,  Hefei University of Technology and the Chinese Academy of Sciences, in Beijing, and Yale University. The first author was Shouwei Zhang, whose name appears on at least seven papers flagged on PubPeer for problematic images. 

The senior author was  Xiangke Wang, whose tally of PubPeer entries is now at 76 and who now has 14 retractions. One of those, the 2013 article “Superior adsorption capacity of hierarchical iron oxide@magnesium silicate magnetic nanorods for fast removal of organic pollutants from aqueous solution,” was retracted from the Journal of Materials Chemistry A on September 13, with the following notice

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Biotech’s data supporting Alzheimer’s trials under scrutiny

A law firm known for filing shareholder suits says that data supporting a drug company’s plan for trials of its experimental treatment for Alzheimer’s disease show evidence of manipulation.

Stock in the company, Cassava Biosciences, tumbled yesterday after the FDA posted material from the firm, Labaton Sucharow, and a top research integrity expert tells Retraction Watch he sees near-certain signs of fabrication in the data.

Earlier this week, Labaton Sucharow submitted a “citizen’s petition” to the FDA regarding a regulatory filing from Cassava, and called on the agency to halt trials of Cassava’s drug simulfilam on the grounds that it had: 

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Journals retract papers following publication of university investigation by Retraction Watch

Hari Koul

Two journals have retracted three papers by a former researcher at the University of Colorado Denver six weeks after Retraction Watch first revealed that the university had recommended correcting the research record in 2016. Another journal has issued an expression of concern for a paper flagged in the investigation.

Despite a recommendation that nine different papers be corrected and retracted, journals had, by last month, retracted just two papers by the researcher, Hari Koul, now at Louisiana State University, and corrected one. Koul, as we reported, had apparently failed to inform multiple journal editors of the need for corrections and retractions.

At the time, Jennifer Regala, the executive editor of the Journal of Urology, which just retracted two of Koul’s papers, told Retraction Watch: “We were not aware of these allegations, so of course these are of grave concern to us.” She said that the American Urological Association, which publishes the journal, planned to conduct its own investigation. 

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Exclusive: Six years after a misconduct investigation, more than half of suspect papers remain unflagged

Hari Koul

When the University of Colorado at Denver completed an investigation in 2015 into the work of a former faculty member, the school recommended that nine papers be corrected or retracted.

But six years after the close of that investigation, the researcher, urologist Hari Koul, has had just two papers retracted and one corrected. 

Multiple journal editors told Retraction Watch they had not been informed that papers published in their journals were recommended for retraction or correction, according to documents obtained by Retraction Watch via a public records request. And emails show Koul was still negotiating the retraction of at least one of the papers last year.

Continue reading Exclusive: Six years after a misconduct investigation, more than half of suspect papers remain unflagged

On the perils of scientific collaboration from thousands of miles away

David Ojcius

Collaborations can be fraught. Ask David Ojcius. 

Ojcius, an emeritus professor of molecular and cell biology at the University of California, Merced, and a department chair at the University of the Pacific, is up to four retractions, five corrections and an expression of concern in papers he wrote with collaborators in China and elsewhere. 

Ojcius is the editor-in-chief of Microbes and Infection, which has retracted one of his papers and corrected another. 

Continue reading On the perils of scientific collaboration from thousands of miles away