by journal – Page 6 – Retraction Watch

Former medical school dean earns sixth retraction

A kidney researcher and former dean of a medical school has now had six papers retracted and one marked with an expression of concern in a little more than a year.

The latest retraction for Joseph I. Shapiro, of a 2015 paper in Science Advances, comes two years after PubPeer commenters began posting about potentially duplicated images in the article, and one year after the authors corrected two of its figures.

Shapiro, the corresponding author on the article, stepped down as dean of the Joan C. Edwards School of Medicine at Marshall University in Huntington, W. Va., on June 30th of this year, but remains a tenured professor at the institution. Neither he nor Komal Sodhi, the first author on the article and also of Marshall, have responded to our request for comment.

Retractions of work Shapiro led began last September, according to our database, following critical comments on PubPeer.

Paper by gene therapy Zolgensma developer retracted because of discrepancies in mouse survival rates

A paper describing preclinical work that was foundational for the gene therapy for spinal muscular atrophy now sold as Zolgensma has been retracted for data inaccuracies.

The article, “Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN,” was published in Nature Biotechnology in 2010. Its corresponding author, Brian Kaspar, was at The Ohio State University at the time. Kaspar went on to become the scientific founder and chief scientific officer of AveXis, which created Zolgensma and was acquired by Novartis in 2018 for $8.7 billion.

The paper has been cited 557 times, according to Clarivate’s Web of Science, and referenced in at least 59 patents, according to Altmetric.

According to the retraction notice, the authors contacted the journal last year about “inaccuracies” in the data. After the journal’s investigation, the editors decided to retract the article over the author’s objections. The notice explained:

Med school vice dean says he’s correcting paper amid negative misconduct inquiry

A gastroenterology research group led by a vice dean at a medical school has requested that a journal correct a paper with an image duplicated from an earlier study by the same group, Retraction Watch has learned. The journal has not yet determined what kind of notice to place on the article.

The group’s leader informed us of the correction request in emails asking us to remove a comment on a post from June pointing out the duplicated image. He also told us that he requested the correction before his employer received an allegation of research misconduct and started an inquiry, which found he and his group had not committed research misconduct.

Uma Sundaram, vice dean of research and graduate education at the Joan C. Edwards School of Medicine of Marshall University in Huntington, W. Va. and chair of the department of clinical and translational science, is corresponding author on both of the papers that share an image. Sundaram also has a dual appointment at a VA medical center in Huntington.

One chiropractic manipulation patient injury. Two case reports. Two editor’s notes.

What happens when two different groups from two different medical specialties see a patient, and then write up separate case reports?

Ask teams of doctors in the neurology and rheumatology departments of the Faculdade de Medicina, Universidade de São Paulo in Brazil. They both published case reports about a patient was injured after undergoing chiropractic spinal cord manipulation. And now both journals have editor’s notes acknowledging dual publication.

The patient’s case appeared in Neurology as “Spinal Cord Injury, Vertebral Artery Dissection, and Cerebellar Strokes After Chiropractic Manipulation” and as “Breaking the diagnosis: ankylosing spondylitis evidenced by cervical fracture following spine manipulation” in the journal Internal and Emergency Medicine. The two publications included the same figure and reported many of the same details about the patient with undiagnosed ankylosing spondylitis who experienced spinal cord injury and cerebellar strokes after experiencing spinal cord manipulation.

The editors of both journals published notes flagging the cases, an expression of concern in Internal and Emergency Medicine and a “notice of dual publication” in Neurology.

The notices are nearly identical, and state, in part:

Exclusive: NIH researcher resigned amid retractions, including Nature paper

A tenure-track investigator at the National Institute of Environmental Health Sciences (NIEHS), a division of the National Institutes of Health, resigned in March, as questions mounted about her work, Retraction Watch has learned.

Jennifer Martinez has retracted at least two papers, including a 2016 Nature paper with the chair of the immunology department at St. Jude Children’s Research Hospital in Memphis, Tenn., and has another marked with an expression of concern.

The retraction is the first for Douglas R. Green of St. Jude, although he’s had a handful of corrections and two other papers he published in Nature have been questioned by scientists who couldn’t replicate the results.

After a postdoc at St. Jude, Martinez led an independent research program at NIEHS in Research Triangle Park, North Carolina since 2015, according to an online CV. She resigned from NIEHS in March and a federal research watchdog is looking into her work, a spokesperson told us:

Nobel Prize winner Gregg Semenza retracts four papers

A Johns Hopkins researcher who shared the 2019 Nobel Prize in Medicine or Physiology has retracted four papers from the Proceedings of the National Academy of Sciences (PNAS) for concerns about images in the articles.

Gregg Semenza is “one of today’s preeminent researchers on the molecular mechanisms of oxygen regulation,” the work for which he shared the 2019 Nobel, according to Hopkins. But even before that, the pseudonymous Claire Francis began pointing out potential image duplications and other manipulations in Semenza’s work on PubPeer, as described in October 2020 by Leonid Schneider.

The four papers retracted yesterday are:

‘It’s time to devise a more efficient solution’: Science editor in chief wants to change the retraction process

On the heels of a high-profile retraction that followed deep investigations by the Science news team, Holden Thorp, the editor in chief of the journal, says it’s time to improve the process of correcting the scientific record.

In an editorial published today, Thorp, a former university provost, describes the often time-consuming and frustrating process involving journals, universities, and government agencies that are often at odds, or at least have different priorities. Based on the experience of what can feel like gridlock, he calls for breaking the process into two stages:

Science retracts coral reef recovery paper more than a year after a report on allegations in its own pages

Fifteen months after its news division published an investigation into work on coral reef recovery, Science has retracted a 2014 paper on the subject.

The article, “Chemically mediated behavior of recruiting corals and fishes: A tipping point that may limit reef recovery,” was written by a group at Georgia Institute of Technology led by Danielle Dixson, then a postdoc at the university. Science issued an expression of concern in February of this year, as we reported then.

According to the retraction notice, signed by Science editor in chief Holden Thorp, the University of Delaware, Lewes, where Dixson has been running her own lab, “no longer [has] confidence in the validity of the data”:

Exclusive: PLOS ONE to retract more than 100 papers for manipulated peer review

In March, an editor at PLOS ONE noticed something odd among a stack of agriculture manuscripts he was handling. One author had submitted at least 40 manuscripts over a 10-month period, much more than expected from any one person.

The editor told the ethics team at the journal about the anomaly, and they started an investigation. Looking at the author lists and academic editors who managed peer review for the papers, the team found that some names kept popping up repeatedly.

Within a month, the initial list of 50 papers under investigation expanded to more than 300 submissions received since 2020 – about 100 of them already published – with concerns about improper authorship and conflicts of interest that compromised peer review.

Papers in Scientific Reports – and their expressions of concern – raise questions

Has Springer Nature’s Scientific Reports been targeted with an authorship for sale scheme? At least one expert in such matters thinks so.

The journal has issued two recent expressions of concern for papers by researchers from Indonesia, Iran and Russia with highly unusual – and oddly similar – constellations of authors.

One 2021 article, “Numerical investigation of nanofluid flow using CFD and fuzzy-based particle swarm optimization,” drew a significant amount of attention on PubPeer. In January, a commenter pointed out a variety of apparent problems with the paper and noted that questions have been raised about other work by members of the group – including this now-retracted article in … Scientific Reports.

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