After 15 years of controversy, Science retracts ‘arsenic life’ paper

Science has retracted a 2010 paper describing a strain of bacteria that purportedly substituted arsenic for phosphorus, an element present in all known life.
Science/AAAS

Fifteen years after publishing an explosive but long-criticized paper claiming to describe a microbe that could substitute arsenic for phosphate in its chemical makeup, Science is retracting the article, citing “expanded” criteria for retraction. 

The authors stand by their findings and disagree with the retraction, and contend the decision doesn’t reflect best practices for publishers. 

Many scientists, including David Sanders, a biologist at Purdue University in West Lafayette, Ind. who has previously argued for the paper’s retraction in posts for Retraction Watch, believe the paper’s results were simply the result of contamination of the authors’ materials. He told us he was “glad” to see the retraction. 

Continue reading After 15 years of controversy, Science retracts ‘arsenic life’ paper

Misconduct investigation at U.S. military university uncovers image duplication

Authors affiliated with a federal health sciences university have lost three papers this year for image duplication following an investigation by the institution. And another journal has confirmed it will retract a fourth paper by some of the same authors.

The “internal research misconduct investigation” conducted by the Uniformed Services University, or USU, in Bethesda, Md., found “several falsified or inappropriately duplicated images” and “images from previously published articles,” according to two of the retraction notices. USU, an institution focused on military medicine and part of the U.S. Department of Defense, acknowledged our multiple requests for comment about the investigation but did not provide a statement.

In January, Retraction Watch filed a Freedom of Information Act request about the investigation. The Department of Defense acknowledged our request on January 7, noting the agency has 4,552 open requests that are processed in the order in which they are received.

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Director of Cambridge toxicology institute retracts paper for potential image manipulation

Twelve years after sleuths flagged problematic images in a 2009 paper, the authors — including the head of a UK research institute — have retracted the article.  

The paper, published in Genes & Development, has been cited 126 times, according to Clarivate’s Web of Science.

According to the June 1 retraction notice, the authors retracted the paper because of “anomalies in the data presented” in multiple figures. “The issues relate to potential instances of image manipulation, including undisclosed splicing, lane flipping, and lane and panel duplications in the preparation of these figures.”

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Wake Forest cancer lab blames ‘honest mistakes’ for retractions

A prominent cancer research lab is up to three retractions and six corrections for “highly similar” images in papers published between 2018 and 2022. 

The lab is led by Kounosuke Watabe at Wake Forest University School of Medicine in Winston-Salem, North Carolina. Watabe holds one of three Wake Forest professorships all funded by a $2.8 million donation for cancer research in 2016. 

Each of the retractions and corrections came after sleuth Kevin Patrick raised concerns about the articles on PubPeer in May 2024. Patrick, who identified instances of images in Watabe lab papers being “more similar than expected,” told Retraction Watch he wasn’t confident whether the image duplication could be attributed to misconduct. “I am never sure which is worse, misconduct or a pattern of errors. Neither seem to inspire confidence in the published results,” he said. 

Watabe did not respond to multiple requests for comment.

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Retraction for ‘unsound’ analysis was ‘disproportionate and discouraging,’ author says

The editors of Scientific Reports have retracted an article on burnout because the statistical analysis of its main finding was “unsound.” But the authors dispute the editors’ take on the statistics and claim a mistake in the paper triggered an unfair review.

For the paper, published in November, the authors measured concentrations of cortisol in hair samples from nearly 500 healthcare workers in Buenos Aires to study the effect of the COVID-19 pandemic on chronic stress and burnout. The analysis hinged on a statistical method called mediation analysis.

“Mediation analysis is a method to understand how one thing causes another by looking at what happens in between,” said lead author Federico Fortuna, of the Institute of Physiopathology and Clinical Biochemistry at the University of Buenos Aires. “In our study, we examined whether depersonalisation mediates the relationship between hair cortisol — a biological stress marker — and emotional exhaustion, a key psychological symptom of burnout.”

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When it comes to conflicts of interest, affiliations are apparently no smoking gun

Seven papers on various aspects of vaping and cigarettes published in Toxicology Reports listed each authors’ affiliation –  the tobacco company Philip Morris International – when they originally appeared in the journal between 2019 and 2023. And all but one article disclosed the funding for the research originated from the company. 

That apparently wasn’t enough for the journal.

Toxicology Reports has issued a correction to add those affiliations as a conflict of interest. The statements were “missing or incorrect” in the original papers, according to the correction notice, published in the June 2025 issue of Toxicology Reports. In addition to reiterating that the authors work for PMI, the correction also adds to the conflict of interest statements that the authors were funded by the company and used its products in the research.

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Viral paper on black plastic kitchen utensils earns second correction

The authors of a paper that went viral with attention-grabbing headlines urging people to throw out their black plastic kitchen tools have corrected the work for a second time.

But a letter accompanying the correction suggests the latest update still fails “to completely correct the math and methodological errors present in the study,” according to Mark Jones, an industrial chemist and consultant who has been following the case. “The errors are sufficient to warrant a restating of the abstract, sections of the paper and conclusions, if not a retraction.”

The paper, “From e-waste to living space: Flame retardants contaminating household items add to concern about plastic recycling,” originally appeared in Chemosphere in September. The study authors, from the advocacy group Toxic-Free Future and the Amsterdam Institute for Life and Environment at Vrije Universiteit Amsterdam, looked for the presence of flame retardants in certain household plastic items, including toys, food service trays and kitchen utensils. 

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Science issues correction on a paper after repeat experiments and misconduct finding

Science has changed an expression of concern on a 2022 paper to an erratum after removing one of the coauthors — who was found to have committed misconduct — and allowing the researchers to repeat experiments.

The paper, “Structural basis for strychnine activation of human bitter taste receptor TAS2R46,” has been cited 68 times, according to Clarivate’s Web of Science. 

Two months after publishing the article in September 2022, Science issued an editorial expression of concern, stating a post-publication analysis had found one figure with “potential discrepancies.”

Continue reading Science issues correction on a paper after repeat experiments and misconduct finding

Apparent NCI director candidate wants ‘open, respectful’ post-publication peer review while promoting anonymous site that calls sleuths a ‘mob’

Wafik S. El-Deiry

Brown University physician-scientist Wafik El-Deiry has been a longtime critic of the post-publication forum PubPeer, where 75 of his papers have been flagged. For example, in an April post on X, formerly Twitter, he stated, “It is not good that PubPeer has been weaponized and has become tyrannical.” In July 2024, he referred to the emails authors receive when someone posts a comment about their papers as being “under attack by PubPeer and their anonymous mob.”

PubPeer, started in 2012, won the 2024 Einstein Award For Promoting Quality in Research. (Disclosure: Our co-founder Ivan Oransky is a volunteer member of the board of directors of the PubPeer Foundation.)

In April, a site called Science Guardians, an “online journal club” with remarkable similarities – but also key differences – to PubPeer, launched what it called an “investigation” into PubPeer. Since then the anonymous account has posted numerous posts on X critiquing PubPeer while promising to reveal the “perpetrators of the PubPeer Network Mob.” 

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10 years after the downfall of a same-sex marriage canvassing study, tenure, some better practices — and an engagement

A study on how conversations can change minds grabbed headlines when it was published — and again five months later when retracted.

“Gay Advocates Can Shift Same-Sex Marriage Views,” read the New York Times headline. “Doorstep visits change attitudes on gay marriage,” declared the Los Angeles Times. “Cure Homophobia With This One Weird Trick!” Slate spouted.

Driving those headlines was a December 2014 study in Science, by Michael J. LaCour, then a Ph.D. student at the University of California, Los Angeles, and Donald Green, a professor at Columbia University.

Researchers praised the “buzzy new study,” as Slate called it at the time, for its robust effects and impressive results. The key finding: A brief conversation with a gay door-to-door canvasser could change the mind of someone opposed to same-sex marriage. 

By the time the study was published, David Broockman, then a graduate student at the University of California, Berkeley, had already seen LaCour’s results and was keen to pursue his own version of it. He and fellow graduate student Joshua Kalla had collaborated before and wanted to look more closely at the impact canvassing could have on elections. But as the pair deconstructed LaCour’s study to figure out how to replicate it, they hit several curious stumbling blocks. And when they got a hold of LaCour’s dataset, or replication package, they quickly realized the results weren’t adding up. 

Continue reading 10 years after the downfall of a same-sex marriage canvassing study, tenure, some better practices — and an engagement