Researchers from The Ohio State University and The Scripps Research Institute are retracting a 2013 paper in Proceedings of the National Academy of Sciences after they uncovered data irregularities.
The retraction notice for “Somatic hypermutation maintains antibody thermodynamic stability during affinity maturation,” will appear online on Sept. 5. The paper purported to find clues about what makes antibodies stable at different temperatures. In a press release issued at the time of publication, corresponding author Thomas Magliery, of The Ohio State University, said the paper might help pharmaceutical companies make better antibody-based drugs. It has been cited 36 times, according to Clarivate Analytics’ Web of Science.
At some point — we’re not exactly sure when — the authors discovered that the antibody stability data was suspect. According to the notice: Continue reading PNAS retracts paper linked to ex-Ohio State researcher who had chemistry PhD revoked