Two retractions as yeast researcher risks losing her PhD

Saccharomyces cerevisiae cells in DIC microscopy via Wikimedia

A team of researchers in France has lost two papers on their studies of yeast because the work was “a complete work of fiction,” in the words of one colleague.

The papers came from the lab of Jean-Luc Parrou, of the University of Toulouse, and involved work by a former PhD student of his named Marjorie Petitjean. According to Parrou, institutional investigators are now in the process of revoking her degree, but have been delayed by the Covid-19 pandemic. We could not find contact information for Petitjean.

One of the articles, “Yeast tolerance to various stresses relies on the trehalose-6P synthase (Tps1) protein, not on trehalose,” appeared last year in the Journal of Biological Chemistry. It has been cited 54 times, according to Clarivate Analytics’ Web of Science. The other, “A new function for the yeast Trehalose-6P Synthase (Tps1) Protein, as key pro-survival factor during growth, chronological ageing, and apoptotic stress,” was published in Mechanisms of Ageing and Development in 2017. It has been cited 11 times. 

The retraction notice from JBC reads

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Materials scientist up to nine retractions

An itinerant materials scientist whose former lab head has accused publicly of misconduct is up to nine retractions for manipulating his data. 

We last wrote about Hossein Hosseinkhani in 2016, after he’d lost seven papers stemming from his time as a researcher in the lab of Yasuhiko Tabata, of the Institute for Frontier Life and Medical Sciences at Kyoto University in Japan. 

Since then, the researcher has lost two more articles, including, most recently, a 2001 article he wrote with Tabata that appeared in the Proceedings of the Japanese Academy of Sciences. According to the retraction notice for the paper, titled “In vitro transfection of plasmid DNA by different cationized gelatin with or without ultrasound irradiation.”

The notice reads: 

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Litigious OSU cancer researcher earns his 10th retraction

Carlo Croce

Carlo Croce, the prolific cancer researcher at The Ohio State University (OSU) with a penchant for hiring — and then losing — lawyers to sue those who displease him, has lost an 10th paper to retraction.

Croce, who in addition to the 10 retractions also has three expressions of concern and 18 corrections for his work, unsuccessfully sued the New York Times for defamation after the newspaper reported on misconduct allegations against him. He has also sued OSU — also unsuccessfully — to force them to restore him as chair of the Department of Cancer Biology and Genetics. 

Apparently, Croce and his co-author thought that a correction to the newly retracted article was necessary because of “improper reuse of text from previous articles.” The journal, however, felt differently.

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A German vocabulary lesson: Paper retracted because an “individuelle Heilversuche” is not a clinical trial

by mcmurryjulie

A co-editor of the Journal of Neurology has retracted a 2018 paper he helped write because the way the paper was written misled readers about the nature of the research. 

The article, “Menière’s disease: combined pharmacotherapy with betahistine and the MAO-B inhibitor selegiline—an observational study,” purported to describe the effects of a combination treatment to reduce the incidence of dizziness in people with Menière’s, a neurologic disorder that affects the inner ear. 

The first author of the paper is Michael Strupp, of the Munich Center for Neurosciences at Ludwig-Maximilians-University in Munich. Strupp also is one of a troika of editors in-chief of the Journal of Neurology.

According to the abstract: 

Continue reading A German vocabulary lesson: Paper retracted because an “individuelle Heilversuche” is not a clinical trial

Frustrated by a university’s lack of action, a journal retracts

Expression of concern, meet expression of frustration.

Eight months ago, in the wake of skepticism about the data in a 2017 paper it had published, the Obstetrics & Gynecology issued an EoC about the article. At the time, the journal, an official title of the American College of Obstetricians and Gynecologists, said it had contacted the authors’ institution — Menoufia University in Shibin Al Kawm, Egypt — about the article.

Those efforts evidently met with silence. Now the journal has retracted the paper, “Sildenafil citrate therapy for oligohydramnios: a randomized controlled trial,” with a swipe at the school’s apparent lack of interest in the misdeeds of its faculty members: 

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Researcher loses PhD after investigation finds he faked data

Researchers in Singapore have lost a 2011 paper in Gene Therapy after an institutional investigation found that some of their data had been fabricated by a PhD student on the project.

Most of the authors were affiliated with the Institute of Bioengineering and Nanotechnology, a unit of the Agency for Science, Technology and Research (A*STAR). 

The article, “Targeted suicide gene therapy for glioma using human embryonic stem cell-derived neural stem cells genetically modified by baculoviral vectors,” purported to show that: 

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Investigation at Japanese university leads to four retractions

Kobe Gakuin University via Wikimedia

A group of pharmacology researchers in Japan have now lost four papers over concerns about the validity of their data.  

The studies come from a group at Kobe Gakuin University, which conducted a misconduct investigation into the articles last year and concluded that 10 papers were affected. (Note: The report is in Japanese and does not identify the person or persons responsible for the deception.)

Among the latest to be retracted is a 2012 article in the Journal of Natural Medicines titled “Honokiol suppresses the development of post-ischemic glucose intolerance and neuronal damage in mice.”

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Four retractions follow misconduct inquiry at U Maryland

via Wikimedia

The Journal of Virology has retracted three papers, and corrected two others, by a group led by a researcher at the University of Maryland, for problematic images. 

The articles, published in 2008 and 2014, describe experiments to assess the immune response to Newcastle disease virus in various animal species.  The studies were led by Siba K. Samal, a molecular biologist at the Virginia-Maryland Regional College of Veterinary Medicine at the University of Maryland, in College Park.

The retractions make four for Samal, who also lost a 2015 paper in the Journal of Clinical Microbiology, “Glycoprotein-based enzyme-linked immunosorbent assays for serodiagnosis of infectious laryngotracheitis,” and whose work has been scrutinized on PubPeer for more than four years. The notice for that paper reads: 

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Letter on vaping science paper earns expression of concern because author made up a degree

via Wikimedia

Leonard Zelig, meet Zvi Herzig.

The journal Circulation has issued an expression of concern about a 2015 letter, putatively written by Herzig, in which the author poked holes in a review article about e-cigarettes. 

According to the EoC, however, Herzig, like Zelig, may be a bit of a chameleon.

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Researcher formerly of OSU and Taiwan’s Academia Sinica gets 10-year ban

After a 20-month investigation, Taiwan’s leading science institution has hit a former star cancer researcher with a 10-year ban for research misconduct. 

Academia Sinica (AS) said its inquiry found that Ching-shih Chen, formerly a distinguished research fellow at the center, was guilty of fabricating or falsifying data in several of the nearly two dozen papers he’d published while affiliated with the institution from 2014 to 2018. AS said Chen was being directed to retract one of the affected papers and correct three others. 

A 2018 article in the Taipei Times quoted an AS official, Henry Sun, saying that Chen, who resigned his post there that year, admitted that his staff had “beautified” his results and that he kept loose reins over this lab. 

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