Cell retraction for bogus images in genetics paper reveals another, in Journal of Molecular Biology

Call it bad luck, but the journal Cell has been victimized again by image manipulation. For the second time this month, the publication has retracted a paper whose authors acknowledged that one of them had played around with the figures.

Published in August 2009, the paper, “Population-Level Transcription Cycles Derive from Stochastic Timing of Single-Cell Transcription,” has been cited 16 times, according to Thomson Scientific’s Web of Knowledge. It purported to show using computer modeling that

transcriptional cycling, i.e., periodic assembly of transcription factors and their cofactors and the resulting cyclical accumulation of mRNA, may stem from stochastic timing and sequential activation of transcription in individual cells.

The authors, from several European institutions, presented experimental data to back up their computer model, including multiple figures. Some of those, they now admit, were fabricated — to the point where the whole paper collapsed: Continue reading Cell retraction for bogus images in genetics paper reveals another, in Journal of Molecular Biology