Kate Travis

Panel upholds results of contested U Toronto mammography study

The University of Toronto has quietly published the results of an inquiry into the Canadian National Breast Screening Study that began in 2022 and, it seems, concluded in March 2024.

The panel, tasked with evaluating new allegations about the trial’s randomization, found the evidence it reviewed did not affect the results of the trials, which called into question the value of mammography in women ages 40-59.

Imaging scientist Martin Yaffe of the University of Toronto has long been a critic of the CNBSS, a pair of randomized clinical trials of mammography conducted in the 1980s. In April, we published a guest post in which Yaffe detailed the history of the trial and his critiques of it, as well as new evidence that clinical staff may have unwittingly influenced randomization. He reported this to the Canadian Cancer Society in 2021, and to the university.

Retraction for ‘unsound’ analysis was ‘disproportionate and discouraging,’ author says

The editors of Scientific Reports have retracted an article on burnout because the statistical analysis of its main finding was “unsound.” But the authors dispute the editors’ take on the statistics and claim a mistake in the paper triggered an unfair review.

For the paper, published in November, the authors measured concentrations of cortisol in hair samples from nearly 500 healthcare workers in Buenos Aires to study the effect of the COVID-19 pandemic on chronic stress and burnout. The analysis hinged on a statistical method called mediation analysis.

“Mediation analysis is a method to understand how one thing causes another by looking at what happens in between,” said lead author Federico Fortuna, of the Institute of Physiopathology and Clinical Biochemistry at the University of Buenos Aires. “In our study, we examined whether depersonalisation mediates the relationship between hair cortisol — a biological stress marker — and emotional exhaustion, a key psychological symptom of burnout.”

Viral paper on black plastic kitchen utensils earns second correction

The authors of a paper that went viral with attention-grabbing headlines urging people to throw out their black plastic kitchen tools have corrected the work for a second time.

But a letter accompanying the correction suggests the latest update still fails “to completely correct the math and methodological errors present in the study,” according to Mark Jones, an industrial chemist and consultant who has been following the case. “The errors are sufficient to warrant a restating of the abstract, sections of the paper and conclusions, if not a retraction.”

The paper, “From e-waste to living space: Flame retardants contaminating household items add to concern about plastic recycling,” originally appeared in Chemosphere in September. The study authors, from the advocacy group Toxic-Free Future and the Amsterdam Institute for Life and Environment at Vrije Universiteit Amsterdam, looked for the presence of flame retardants in certain household plastic items, including toys, food service trays and kitchen utensils.

When PubMed got it right, Elsevier got it wrong, and Retraction Watch helped clear it up

More than 20 years after publishing a letter saying a set of papers should be retracted — and PubMed marking them as such — the journal has finally retracted the articles, following a Retraction Watch inquiry.

Let’s back up.

In 1998, the journal Contraception published a supplement with six articles on Implanon, a subdermal contraceptive implant. The papers examined the implant’s pharmacodynamics and side effects. The next year, the journal published two clinical studies of the implant, one on its effectiveness as a contraceptive and the other on its effect on lipid metabolism.

Those two studies took place at centers in Jakarta, Indonesia. Some of the study data published in the supplement also included patients at those centers.

Apparent NCI director candidate wants ‘open, respectful’ post-publication peer review while promoting anonymous site that calls sleuths a ‘mob’

Brown University physician-scientist Wafik El-Deiry has been a longtime critic of the post-publication forum PubPeer, where 75 of his papers have been flagged. For example, in an April post on X, formerly Twitter, he stated, “It is not good that PubPeer has been weaponized and has become tyrannical.” In July 2024, he referred to the emails authors receive when someone posts a comment about their papers as being “under attack by PubPeer and their anonymous mob.”

PubPeer, started in 2012, won the 2024 Einstein Award For Promoting Quality in Research. (Disclosure: Our co-founder Ivan Oransky is a volunteer member of the board of directors of the PubPeer Foundation.)

In April, a site called Science Guardians, an “online journal club” with remarkable similarities – but also key differences – to PubPeer, launched what it called an “investigation” into PubPeer. Since then the anonymous account has posted numerous posts on X critiquing PubPeer while promising to reveal the “perpetrators of the PubPeer Network Mob.”

10 years after the downfall of a same-sex marriage canvassing study, tenure, some better practices — and an engagement

A study on how conversations can change minds grabbed headlines when it was published — and again five months later when retracted.

“Gay Advocates Can Shift Same-Sex Marriage Views,” read the New York Times headline. “Doorstep visits change attitudes on gay marriage,” declared the Los Angeles Times. “Cure Homophobia With This One Weird Trick!” Slate spouted.

Driving those headlines was a December 2014 study in Science, by Michael J. LaCour, then a Ph.D. student at the University of California, Los Angeles, and Donald Green, a professor at Columbia University.

Researchers praised the “buzzy new study,” as Slate called it at the time, for its robust effects and impressive results. The key finding: A brief conversation with a gay door-to-door canvasser could change the mind of someone opposed to same-sex marriage.

By the time the study was published, David Broockman, then a graduate student at the University of California, Berkeley, had already seen LaCour’s results and was keen to pursue his own version of it. He and fellow graduate student Joshua Kalla had collaborated before and wanted to look more closely at the impact canvassing could have on elections. But as the pair deconstructed LaCour’s study to figure out how to replicate it, they hit several curious stumbling blocks. And when they got a hold of LaCour’s dataset, or replication package, they quickly realized the results weren’t adding up.

Fourth retraction for Italian scientist comes 11 years after sleuths flagged paper

PLOS One has retracted a 2011 paper first flagged for image issues 11 years ago. The retraction marks the fourth for the paper’s lead author, Gabriella Marfè of the University of Campania “Luigi Vanvitelli,” in Caserta, Italy.

“Involvement of FOXO Transcription Factors, TRAIL-FasL/Fas, and Sirtuin Proteins Family in Canine Coronavirus Type II-Induced Apoptosis,” has been cited 41 times, according to Clarivate’s Web of Science.

Elisabeth Bik flagged the article on PubPeer in 2014 for apparent image manipulation and duplication in six figures. In a 2019 email to PLOS staff, pseudonymous sleuth Claire Francis drew attention to Bik’s findings. The journal retracted the paper on May 6 of this year.

IQ study retracted in fallout from decades-old misconduct report

The authors of a paper on how motivation influences intelligence test scores have retracted their paper following the retraction of a 50-year-old study included in their analysis.

Part meta-analysis and part longitudinal study, “Role of test motivation in intelligence testing” appeared in Proceedings of the National Academy of Sciences in 2011. The meta-analysis portion included a 1978 paper by Stephen Breuning, a child psychologist who was the subject of 1987 report from the National Institute of Mental Health that found he “knowingly, willfully, and repeatedly” engaged in research misconduct and fabricated results in 10 NIMH funded articles.

As we reported earlier this year, six of Breuning’s papers have been retracted, including one last December. That article, published in 1978 in the Journal of School Psychology, found record albums, sporting event tickets, portable radios, and other incentives boosted scores on IQ tests.

Genentech authors flip PNAS study from corrected to retracted following Retraction Watch coverage

The authors of a 2006 paper have retracted their article following an extensive correction in January – and a Retraction Watch story noting the correction missed at least one additional issue with the work.

“Death-receptor activation halts clathrin-dependent endocytosis,” published in July 2006 in Proceedings of the National Academy of Sciences, has been cited 99 times, according to Clarivate’s Web of Science. Most of the authors were affiliated with the biotech company Genentech.

As we previously reported, commenters on PubPeer raised issues about possible image duplications, spurring the authors to review the work. The January correction addressed about two dozen instances of image splicing and duplication in five of the paper’s figures. The notice stated the authors repeated the experiments for a manuscript posted on bioRxiv in October 2024. “The new data confirms the original results, reaffirming the experimental conclusions,” the authors wrote in the correction notice.

Elsevier removes journal from Scopus after Retraction Watch inquiry

Elsevier has removed a journal from its Scopus database after Retraction Watch inquired about its review process for the journal, whose editorial board lists fake names and digital fingerprint shows other red flags.

Scientific sleuth Anna Abalkina uncovered several issues with Science of Law, which she details in a post published today. Besides editors and editorial board members who cannot be verified and don’t seem to exist, the journal’s history doesn’t match its publication record, early articles show signs of fabrication, and its publisher data in Scopus doesn’t match that in Crossref. Despite this, Scopus added the journal to its index last year.

To understand how these problems could have evaded reviewers at Scopus, we asked Elsevier if Scopus staff verifies editorial board members when vetting journals, and if they assess the quality and validity of articles in journals before adding them to the index.

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