Two and a half years after critics raised concerns, a dermatology journal says it has called on two French institutions to launch an inquiry into a 2017 paper.
The Journal of Investigative Dermatology has issued an expression of concern for the article, “NADPH Oxidase-1 Plays a Key Role in Keratinocyte Responses to UV Radiation and UVB-Induced Skin Carcinogenesis,” which it published in June 2017.
The authors of the group were led by Hamid Reza Rezvani, the head of the dermatology team at Université de Bordeaux, and a research director with INSERM, France’s publicly funded science agency.
A journal has issued expressions of concern for a pair of 2021 meta-analyses purporting to find that ivermectin is an effective treatment for Covid-19 after data sleuths raised questions about some of the research in the studies.
As we reported last fall, one of the two papers – “Ivermectin for Prevention and Treatment of COVID-19 Infection: A Systematic Review, Meta-analysis, and Trial Sequential Analysis to Inform Clinical Guidelines” – began to wobble when data central to its conclusion were retracted from the journal Viruses. That article has been cited 37 times, according to Clarivate Analytics’ Web of Science, making it a highly-cited, “hot” paper.
The other article was titled “Review of the Emerging Evidence Demonstrating the Efficacy of Ivermectin in the Prophylaxis and Treatment of COVID-19” and was written by a group led by Pierre Kory. Kory is a controversial Wisconsin physician whose ideas about how to treat the infection, and particularly ivermectin, have made him a darling of ivermectin proponents like Joe Rogan.
The two meta-analyses were the subject of an editorial in the November/December 2021 issue of the journal by its editor, Peter Manu, who cautioned that:
A 2018 study in PNAS that claimed to show a biotech company’s platform for creating immunotherapies was better than existing methods has earned an expression of concern over the reproducibility of some of its findings.
The technique was developed by SQZ Biotech, which was founded by MIT’s Robert Langer, a founder or co-founder of numerous biotechs including Moderna, and with whom Roche partnered in 2015.
The paper has been cited 55 times, according to Clarivate Analytics’ Web of Science. According to a press release announcing the work:
A gastroenterology journal has issued expressions of concern for forty articles about a probiotic formulation that has been at the center of a long-running legal saga in the United States and Europe.
The articles appeared in the Journal of Crohn’s and Colitis, the official journal of the European Crohn’s and Colitis Organisation (ECCO) and date back to 2007. All mention a proprietary formulation of probiotics – and therein lies the tale.
A group of heart researchers in China now have four expressions of concern, along with a retraction, for questions about the reliability of their data.
The latest expressions of concern for the team, led by Bu Lang Gao, of Shijiazhuang First Hospital of Hebei Medical University, involves a 2019 paper in Springer Nature’s Scientific Reports titled “Asymmetrical middle cerebral artery bifurcations are more vulnerable to aneurysm formation.”
Here’s the notice for the article, which has been cited 4 times, according to Clarivate Analytics’ Web of Science:
A PLOS journal has issued an expression of concern for a 2018 paper which claimed that ivermectin could be useful as a way to control dengue fever.
In fact, the reason the journal re-examined the article was because the hype about the use of ivermectin for Covid-19 led at least one skeptic to take a closer look at the study – and he didn’t like what he saw.
The article, “Antivirus effectiveness of ivermectin on dengue virus type 2 in Aedes albopictus,” was written by a group in China led by Tie-Long Xu, of the National Institute of Parasitic Diseases at the Chinese Center for Disease Control and Prevention. According to the study, which appeared on PLOS Neglected Tropical Diseases:
A virology journal has issued an expression of concern about a paper claiming that the SARS-CoV-2 virus can damage DNA after one member of the research team raised reservations about the reported findings.
The paper has received a fair amount of attention – particularly among vaccine skeptics who, as critics noted, used the article to buttress their claims that Covid vaccines are unsafe – generating enough buzz on social media and in the news to make it into the top 5% of all articles tracked by Altmetric. TWiV even devoted part of an episode of the show to the findings.
A journal has slapped an expression of concern on a 2021 paper reporting on the utility of self-administered “battlefield” acupuncture in soldiers, citing readers who said the FDA has not approved the devices for that use – a point the authors, who object to the move, dismissed as irrelevant and misleading.
The study, which appeared in Medical Acupuncture, looked at the experiences of a dozen veterans at an Ohio VA hospital who’d purportedly self-administered acupuncture to treat chronic pain. According to this 2010 article from the U.S. military:
The Journal of Neuroscience has slapped expressions of concern on a pair of papers linked to the maker of a controversial drug to treat Alzheimer’s disease.
As we and others have reported, Cassava Sciences has been under intense scrutiny lately. In August, the law firm Labaton Sucharow – who is representing Cassava short sellers – submitted a “citizen’s petition” to the FDA regarding a regulatory filing from the company for its drug simulfilam and called on the agency to halt trials of the experimental medication because it had:
Ettore Majorana, after whom the “Majorana” particle is named By unknown author / Mondadori Collection, public domain
You might say that the third time is not the charm for a paper on some elusive fermions.
For the third time this year, a leading science journal has raised concerns about a paper on the “Majorana” particle, which, if it exists, would hold promise for building a quantum computer.
