by journal – Page 15 – Retraction Watch

Prominent cancer researcher loses nine papers, making 10

Andrew Dannenberg (credit Patricia Kuharic)

The Journal of Biological Chemistry (JBC) has retracted nine papers in bulk by a group of cancer researchers in New York led by the prominent scientist Andrew Dannenberg.

The work of Dannenberg’s group at Weill Cornell — and the figures in particular — has been the subject of scrutiny on PubPeer for more than two years.

The group also lost an article more than a decade ago in The Lancet, bringing their total so far to 10. Cancer Discovery subjected a paper to an expression of concern in August. Much of the tainted work was funded by grants from the U.S. government, as well as from funding authorities in other countries.

According to the notice for 2014’s “p53 protein regulates Hsp90 ATPase activity and thereby Wnt signaling by modulating Aha1 expression“:

Nobel winner retracts paper from Science

A Caltech researcher who shared the 2018 Nobel Prize in Chemistry has retracted a 2019 paper after being unable to replicate the results.

Frances Arnold, who won half of the 2018 prize for her work on the evolution of enzymes, tweeted the news earlier today:

PLOS ONE retracts a paper first flagged in 2015 — and breaks the 100 retraction barrier for 2019

A team of researchers in Saudi Arabia, led by an ex-pat from Johns Hopkins University, has lost three papers for problems with the images in their articles.

The three retractions pushed the journal — which has become a “major retraction engine” for reasons we explain here and here — over 100 for 2019.

In December, PLOS ONE retrcated three papers by the group, led by Michael DeNiro, of the King Khaled Eye Specialist Hospital in Riyadh. First, the journal retracted a 2011 article, “Inhibition of reactive gliosis prevents neovascular growth in the mouse model of oxygen-induced retinopathy,” the co-authors were Falah H Al-Mohanna and Futwan A Al-Mohanna. According to the retraction notice:

How a plagiarized eye image in the NEJM was discovered

The Images in Clinical Medicine section of the New England Journal of Medicine (NEJM) is prime real estate for physicians and others wanting to share a compelling picture with their colleagues. But earlier this month, an eye specialist in Michigan saw double when he looked at the Dec. 5, 2019, installment of the feature.

Depicted was a picture from a pair of eye specialists in India who claimed to have seen a case of a person who’d suffered retinal bleeding after having been struck in the eye by a tennis ball:

Award-winning researcher in India retracts two papers, corrects three

Kithiganahalli Narayanaswamy Balaji, a professor at the Indian Institute of Science in Bangalore, has retracted two papers and corrected three for duplication of images.

Balaji, who won the 2011 Shanti Swarup Bhatnagar Prize from India’s Council of Scientific & Industrial Research (CSIR) “for outstanding contributions to science and technology,” is last author of the five papers, which were published in the Journal of Biological Chemistry (JBC) from 2008 to 2015.

The authors take responsibility for what they call “inadvertent mistakes.” The retraction notice for “Pathogen-specific TLR2 protein activation programs macrophages to induce Wnt-β-catenin signaling,” for example, concludes as follows:

‘Exceptionally silly mistakes’: PLOS ONE flags two papers by Cambridge researcher for image issues

A researcher at the University of Cambridge has had two papers subjected to expressions of concern by the editors of PLOS ONE for image problems.

The expressions of concern for “The Coordination of Cell Growth during Fission Yeast Mating Requires Ras1-GTP Hydrolysis” and “The Role of the RACK1 Ortholog Cpc2p in Modulating Pheromone-Induced Cell Cycle Arrest in Fission Yeast” are extensive. They both refer to multiple “discontinuities,” “similarities,” and other issues.

The common author on the two papers is Graham Ladds, who told Retraction Watch that no other papers would be affected. He said that

Death, retirement, and inability to contact authors leads to retraction of paper first flagged five years ago

More than five years after comments appeared on PubPeer about a 2012 paper in PLoS ONE with a raft of problematic images — and a deceased member of the group whom the corresponding author suggests might have been able to support the validity of the data — the journal has retracted the article.

The article, “Placental expression of CD100, CD72 and CD45 is dysregulated in human miscarriage,” was written by a team of researchers at the Università Politecnica delle Marche, in Ancona, Italy. The first, and corresponding, author of the paper was Teresa Lorenzi, of the school’s Division of Neuroscience and Cell Biology.

The paper has 19 citations, including two in 2019, according to Clarivate Analytics’ Web of Science. The lengthy notice begins with a rundown of 14 questions about three of the paper’s figures. We’ll spare you the entire catalog of ships, but here are a few examples:

Andrew Wakefield’s fraudulent paper on vaccines and autism has been cited more than a thousand times. These researchers tried to figure out why.

Elizabeth Suelzer

Retraction Watch readers are no doubt familiar with one of the most consequential retractions of this century, namely that of the 1998 paper in The Lancet by Andrew Wakefield and others claiming a link between vaccines and autism. What they may also know is that the paper remains one of the most highly cited retracted articles of all time, as demonstrated by our leaderboard of such papers.

With that in mind, six librarians from institutions in Wisconsin had a question: ” What are the characteristics of citations of the retracted 1998 article by Wakefield et al that purported to show an association between the measles-mumps-rubella vaccine and autism?” A paper describing their findings was published on Friday in JAMA Network Open.

We asked corresponding author Elizabeth Suelzer, of the Medical College of Wisconsin, to answer several questions about the paper.

Retraction Watch (RW): Why did you decide to focus on the Wakefield paper, and what were your findings?

Stem cell researchers have papers retracted for image manipulation

A group of dentistry researchers in Japan, whose work on stem cells has been the subject of an institutional investigation, have now lost two papers in PLOS ONE for image problems.

The authors, from Aichi Gakuin University in Nagoya, were led by Makio Mogi, a medicinal biochemist at the school. Mogi asked for at least one of the retractions.

The first article, published in 2013, was titled “Matrix metalloproteinase-3 in odontoblastic cells derived from Ips cells: unique proliferation response as odontoblastic cells derived from ES cells.” It has been cited 18 times, according to Clarivate Analytics’ Web of Science. According to the notice:

PLOS ONE realizes an academic editor had a conflict of interest that the publisher says it now tries harder to avoid

A group of genetics researchers in Italy has lost a 2014 paper in PLOS ONE for a range of image problems and a glaring conflict of interest.

The article, titled “Neuronal differentiation dictates estrogen-dependent survival and ERK1/2 kinetic by means of caveolin-1,” came from a team led by Luca Colucci-D’Amato, of the Second University of Naples.

The retraction notice in PLOS ONE lays out a raft of issues with the paper, for example:

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