‘A display of extreme academic integrity’: A grad student who found a key error praises the original author

Paul Lodder

Last week, we wrote about the story of Paul Lodder, a graduate student at the University of Amsterdam who had been trying without success to replicate the findings of a 2020 paper in Scientific Reports by Rubén Herzog, of the Universidad de Valparaíso in Chile. The paper would end up retracted. At the time, Lodder had not had a chance to respond to our questions about the case. We’re pleased to share his comments as a guest post.

I’ve had a big passion for research into the therapeutic potential of psychedelics ever since I had started my undergraduate in biomedical sciences at Amsterdam University College. I am currently a MSc Artificial Intelligence student and about a year ago, in preparation for a computational neuroscience course, I wanted to expand on the model used by Rubén.

I sent him an e-mail explaining the situation, and requesting some parameters that weren’t detailed in the paper so that I could start running the simulations myself. Rubén responded very quickly and was immediately very helpful with getting me started with running the simulations.

Now that I was able to run the model properly, I wanted to start off with being able to reproduce the paper’s analysis results before looking into expanding. Using the methodology described in the paper, I re-implemented the steps needed to compute the entropy. And indeed, this is where I got some different results as presented in the paper.

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