Archive for the ‘misconduct investigations’ Category
Drug researchers in India have lost their 2013 paper in ACS Medicinal Chemistry Letters because the first author fabricated findings.
The article, by a group from the Maharaja Sayajirao University of Baroda, Vadodara, in Gujarat, was attempting to synthesize and screen novel clot-busting drugs; one compound exhibited the same activity as aspirin or warfarin, but without increasing bleeding time.
Sadly, it appears as if this potential medical advance was not to be. Here’s the retraction notice for “Novel 2-Aminobenzamides as Potential Orally Active Antithrombotic Agents”: Read the rest of this entry »
The authors of a 2011 Science paper that proposed a new way to direct chemical bonds have withdrawn the paper after concerns about the data prompted an investigation and Editorial Expression of Concern last year from the journal. The retraction is the second for the group, which has also had seven other expressions of concern.
After a reader emailed the editors to raise suspicions about the data, corresponding author Christopher W. Bielawski, then based at the University of Texas at Austin, led an investigation of all the figures. It found substantial problems: “In over 50% of the figure parts, the authors deemed the data unreliable due to uncertainty regarding the origin of data or the manner in which the data were processed,” according to the retraction notice.
UT Austin concluded that there had been misconduct, but did not elaborate.
The paper, “Preference for immediate reinforcement over delayed reinforcement: relation between delay discounting and health behavior,” was written by Shane Melanko and Kevin Larkin. It examined whether people who place less importance on the future were also less likely to adopt healthy behaviors, which come with delayed benefits. Melanko, then a doctoral candidate under Larkin, was evidently at one time a psychology student of some promise.
Lawyers one, scientists nil.
Danish judges have overruled scientists in that nation, concluding that a panel of experts erred in finding that physiologist Bente Klarlund Pedersen, of the University of Copenhagen, was guilty of misconduct.
Last September, Pedersen announced that she would fight the ruling of the Danish Committees on Scientific Dishonesty (DCSD, Danish acronym UVVU), which had said she had committed misconduct in four of 12 articles it had examined.
As we reported then, Pedersen’s case is tied to that of another Copenhagen scientist, Milena Penkowa, with whom she had collaborated and who also has been found guilty of scientific misdeeds. (The new ruling does not address Penkowa.) Read the rest of this entry »
Bruce Murdoch, a neuroscientist formerly of the University of Queensland, will appear in court next week to face fraud charges stemming from an investigation that has already led to three retractions, several corrections, and similar charges for one of his colleagues.
The journal Chemical Science has issued an expression of concern over a 2012 article by a pair of Texas researchers whose “unclick reaction” work has been under scrutiny by their institution.
The article, “Homonuclear bond activation using a stable N,N-diamidocarbene,” was written by Kelly M. Wiggins and Christopher W. Bielawski, of UT Austin. It’s the second EoC that we know of for a paper by Wiggins and Bielawski. We covered a previous one, from Science, that appeared in June.
A one-time media favorite is being accused of serious misconduct in three cases where he inserted artificial windpipes into patients and treated them with stem cells. Two of the patients have died; one survives, but needs her airway cleaned every four hours by hospital staff to keep her alive.
A little over two years ago, thoracic surgeon Paolo Macchiarini soared to the top and then sunk to the bottom within days. First, his work implanting artificial tracheas hit the front page of the New York Times. Days later he was placed on house arrest for accusations of fraud and extortion.
We wrote about him a month later, when a paper of his was retracted for plagiarism.
The abstract, “Reduced syntaxin-5 in skeletal muscle of patients with type 2 diabetes is linked to increased diacylglycerol, activation of PKCtheta and impaired insulin signalling,” was presented at the annual meeting of the European Association of the Study of Diabetes. The first author was Kurt Højlund, who now is at the University of Southern Denmark. The second author was Pontus Boström, of the Karolinska Institutet.
A late researcher in Italy who has already been blamed for image manipulation in a PLOS ONE retraction notice has had two more papers retracted, both from Free Radical Biology and Medicine.
The European Heart Journal has issued an expression of concern for a
2014 2001 paper by Don Poldermans, the Dutch heart researcher who stepped down from his post at Erasmus University after being accused of misconduct.
The article, “Bisoprolol reduces cardiac death and myocardial infarction in high-risk patients as long as 2 years after successful major vascular surgery,” appeared in July and reported data from the DECREASE trial. Poldermans, who left Erasmus in 2011, has acknowledged failing to receive informed consent from some patients in one phase of the DECREASE study but denied having fabricated results.