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Retraction Watch

Tracking retractions as a window into the scientific process

Archive for the ‘misconduct investigations’ Category

Danish commitee finds Klarlund Pedersen, Penkowa guilty of scientific dishonesty

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Klarlund Pedersen

Klarlund Pedersen

Two researchers in Denmark are guilty of scientific dishonesty, the Danish Committees on Scientific Dishonesty (DCSD, Danish acronym UVVU) has concluded.

In July, the DCSD said in a draft report that Bente Klarlund Pedersen had acted in a “scientifically dishonest” and “grossly negligent” manner. She — and many of her defenders — responded by saying that while she had made mistakes, she had not committed misconduct. Here’s a key quote from a letter her attorney wrote to the committee: Read the rest of this entry »

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Written by Ivan Oransky

December 19, 2013 at 2:00 pm

France tries husband-wife team for research misconduct in plagiarism case

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Mr Sixou

Michel Sixou

We’re always glad to have guest posts, and here’s one from François-Xavier Coudert, reporting from France.

As we reported the other day, a Nature editorial suggested that police involvement might be an appropriate response to research misconduct. The French seem to agree, based on reports in the media there, as Coudert writes:

A husband-wife team of French odontology researchers at l’université Paul-Sabatier in Toulouse have been on trial in that country for research misconduct. Christine Marchal-Sixou, an associate professor, faces a charge of plagiarism, and Michel Sixou, full professor and dean of the faculty of dental medicine until September, has been charged with complicity. Read the rest of this entry »

Written by amarcus41

December 10, 2013 at 12:00 pm

Nature Medicine retracts MS paper with ghost data by former GSK researcher

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naturemed1213Nearly six months after first expressing concern about the validity of a 2010 paper on multiple sclerosis, Nature Medicine has retracted the article for containing “erroneous” data — which in this case don’t seem to have existed, making them more fabricated than wrong.

The paper, “Crucial role of interleukin-7 in T helper type 17 survival and expansion in autoimmune disease,” came from a group led by Jingwu Zhang, who at the time ran GlaxoSmithKline’s Research and Development Center in Shanghai.

In June, the journal issued an expression of concern about the article after readers discovered problems with the data, as reported by Nature Medicine’s blog.
Read the rest of this entry »

Columbia University misconduct retraction highlights what’s wrong with the retraction process

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jcacoverThe Journal of Clinical Anesthesia has a retraction of a 2006 paper by a group from Columbia University that, to our minds, is the poster child for how not to handle such things.

The article, “Dexmedetomidine infusion is associated with enhanced renal function after thoracic surgery,” was written by Robert J. Frumento, Helene G. Logginidou, Staffan Wahlander, Gebhard Wagener, Hugh R. Playford and Robert N. Sladen, who now is chief of critical care at the institution. The paper has been cited 30 times, according to Thomson Scientific’s Web of Knowledge.

Why do we bother to name all the authors? Here’s why: According to the retraction notice, one of them — but don’t ask which — is guilty of research misconduct: Read the rest of this entry »

Lancet retracts Jikei Heart Study of valsartan following investigation

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logo_lancetThe Lancet has retracted a study of Novartis’ blood pressure drug valsartan (Diovan) that has been subject to an investigation following the retraction of a related study earlier this year.

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Written by Ivan Oransky

September 6, 2013 at 8:30 am

Regrettable, but not scientifically dishonest: Klarlund Pedersen responds to Danish committee

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Klarlund Pedersen

Klarlund Pedersen

A Danish researcher has responded to a draft report of the Danish Committees on Scientific Dishonesty (DCSD) that found she had acted in a “scientifically dishonest” and “grossly negligent” manner.

Bente Klarlund Pedersen, a University of Copenhagen researcher, has published with Milena Penkowa, four of whose papers have been retracted following investigations. In the press, she argued that while she had made mistakes, she had not committed misconduct.

The 57-page letter from Klarlund Pedersen’s attorney to the DCSD responds in detail to the critique of her work, including twelve papers. This passage from the summary gathers the arguments together: Read the rest of this entry »

Written by Ivan Oransky

September 2, 2013 at 9:30 am

Aussie university halts trials of skin cancer drug whose developer has four retractions

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An Australian university has put a hold on trials of an experimental drug for skin cancer whose main developer has been dogged by charges of research misconduct for several years.

The Australian Broadcasting Corporation is reporting that the University of New South Wales has suspended trials of the drug, DZ13, while it investigates the work of Levon Khachigian, who is leading the studies.

According to the news organization, Khachigian and his group were cleared by the school in two prior inquiries. However, additional accusations of misconduct — specifically involving image manipulation and misuse — prompted a third investigation.

We’ve found four retractions of Khachigian’s studies, from the Journal of Biological Chemistry and Biochemical and Biophysical Research Communications, between 2009 and 2010 (before the launch of Retraction Watch).

They are: Read the rest of this entry »

Penkowa notches fourth retraction, in Experimental Neurology

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exp neuroMilena Penkowa, the Danish neuroscientist who resigned from the University of Copenhagen in December 2010 amid suspicions of misconduct, has had another paper retracted.

The new retraction appears in Experimental Neurology. Here’s the notice for “M-CSF deficiency leads to reduced metallothioneins I and II expression and increased tissue damage in the brain stem after 6-aminonicotinamide treatment”: Read the rest of this entry »

University of Utah finds former faculty member guilty of misconduct because of “reckless disregard”

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utahSince last May, we’ve been reporting on a case at the University of Utah involving two retractions and two corrections. When the story first broke, the lab blamed a former worker for inappropriately removing data from the premises, and the university has been investigating. Last month, we reported that Ivana De Domenico, the junior faculty member who was first author on those papers, had left the university, and that senior author Jerry Kaplan had retired.

But the problems went beyond the four papers we reported on, as the Salt Lake Tribune reported on Friday. In a 9-page report provided to the Tribune, the panel overseeing the investigation details its examination of 11 papers. This is the first of six findings: Read the rest of this entry »

Written by Ivan Oransky

August 5, 2013 at 9:30 am

University, funding agency clear researcher Rui Curi of fraud charges

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Rui Curi

Rui Curi

The University of São Paulo and Brazil’s National Council of Technological and Scientific Development funding agency (CNPq) have cleared a researcher of fraud following a six-month investigation.

The CNPq’s Commission on Integrity in Scientific Activity noted, however, that “there was failure to exercise rigor in the conduct and dissemination of results [in Rui Curi's work], essential to quality research.” Read the rest of this entry »

Written by Ivan Oransky

August 4, 2013 at 10:06 am


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