Archive for the ‘nature retractions’ Category
Nature retracted a paper on protein structures today, six years after an investigation at the University of Alabama identified several structures that were “more likely than not falsified and/or fabricated” by one of the authors.
The paper came under scrutiny soon after it was published in 2006. A letter published in Nature that same year pointed out “physically implausible features in the structures it described.” That triggered the investigation at the University of Alabama, the result of which was published in 2009, identifying “nine publications related to the same protein structures that should be retracted from various scientific journals.” Everything was pinned on last author H.M. Krishna Murthy, who the investigation determined was “solely responsible for the fraudulent data.”
A 2009 Nature news article on the investigation declared that the “fraud is the largest ever in protein crystallography.”
We’re not sure what took Nature so long to retract the letter, titled “The structure of complement C3b provides insights into complement activation and regulation.” Here’s the note, which explains that not all the authors agreed to the retraction:
The technique — which claimed to provide a new way to nudge young cells from mice into pluripotency — was initially described in two 2014 Nature papers, both first-authored by Haruko Obokata. However, the papers were soon mired in controversy, corrected, then retracted later that year due to “several critical errors,” some of which were categorized by a RIKEN investigation as misconduct.
Authors have retracted a highly cited Nature letter that purported to discover a much sought-after, stable light source from quantum dots, after they realized the light was actually coming from another source: the glass the dots were affixed to.
When the paper “Non-blinking semiconductor nanocrystals” was published in 2009, it received some media coverage, such as in Chemistry World. That’s partly because very small sources of “non-blinking” light could have wide-ranging, big-picture applications, author Todd Krauss, a physical chemist at the University of Rochester, told us:
Off the top of my head, a quantum computer. Quantum cryptography is another one. People want a stable light source that obeys quantum physics, instead of classic physics.
The retraction note, published Wednesday, explains how the researchers found out the effect was coming from the glass, not quantum dots:
Despite acknowledging in its own pages that two recent high-profile retraction notices turned out to not tell the whole story, Nature will not be updating the original retraction notices, the journal tells us.
We checked in with Nature after it published two Brief Communications Arising regarding two high-profile retractions of papers describing a new method of reprogramming cells to a pluripotent state. (This method is also known as stimulus-triggered acquisition of pluripotency, or STAP.)
We were particularly intrigued by the journal’s plans for the retractions, published in 2014, when an editorial in the September 23 issue about the new BCAs (here and here) suggested the wording of the notices might be problematic: Read the rest of this entry »
A 2011 letter to Nature from Harvard researchers received its second correction today, this time after discovering the researchers conducted experiments in which mice may have “experienced more pain and suffering than originally allowed for.”
That quote comes from an accompanying editorial in the journal, a rare move for a correction to a 2011 letter. But it’s an unusual correction, for a letter that found that a component of a pepper plant appeared to selectively kill cancer cells, leaving healthy cells relatively unscathed.
Here’s the first paragraph from the detailed correction notice, published today: Read the rest of this entry »
Thanks to some eagle-eyed readers, we’ve been alerted to some corrections for high profile stem cell scientist Jacob Hanna that we had missed, bringing our count to one retraction and 13 errata on 10 papers.
The problems in the work range from duplications of images, to inadvertent deletions in figures, to failures by his co-authors to disclose funding sources or conflicts of interest. Hanna is the first or last author on 4 of the papers, and one of several on the rest.
First up, a correction to a Cell paper on which Hanna is the first author:
A nearly ten-year-long series of investigations into a pair of plant physiologists who received millions in funding from the U.S. National Science Foundation has resulted in debarments of less than two years for each of the researchers.
The NSF Office of Inspector General recently posted its close-out report on its decision and a review of the University’s investigation, which had recommended a total of eight retractions or corrections. Although the investigator’s names have been redacted, the text of retractions and corrections quoted in the report corresponds to papers by Read the rest of this entry »
A team of Columbia University biologists has retracted a 2013 Nature paper on the molecular pathways underlying Alzheimer’s disease, the second retraction from the group after a postdoc faked data.
An April report from the Office of Research Integrity (ORI) found
the a first author, former Columbia postdoc Ryousuke Fujita, responsible for “knowingly and intentionally fabricating and falsifying research in seventy-four (74) panels” in three papers: a 2011 Cell paper retracted in 2014, an unpublished manuscript, and this now-retracted Nature paper, “Integrative genomics identifies APOE e4 effectors in Alzheimer’s disease.”
The paper was touted in a Columbia University Medical Center press release as identifying “key molecular pathways” leading to late-onset Alzheimer’s disease. The paper fingered two potential molecular drug targets, as well.
Upon realizing they had experienced a case of mistaken cell-line identity, the authors of a 2014 Nature paper on lung cancer think “it prudent to retract pending more thorough investigation,” as they explain in a notice published Wednesday.
The problem seems to stem from more than just honest error, according to corresponding author Julian Downward, a scientist at the Francis Crick Institute in the UK.
In a 1,215 word statement, sent to us via the Director of Research Communications and Engagement at Cancer Research UK, which funds Downward’s research, Downward told us the backstory not presented in the journal’s retraction note:
Sauer had two papers retracted from Science last year following a university investigation. Here’s the Nature notice for “Histone methylation by the Drosophila epigenetic transcriptional regulator Ash1:” Read the rest of this entry »