Brain tumor researchers lose second paper as UCSF investigates

Russell Pieper

A research group at the University of California, San Francisco, under investigation for potential misconduct has had a second paper retracted.

The group, led by Russell O. Pieper, director of basic science at the UCSF Brain Tumor Center and vice-chairman of the UCSF Department of Neurological Surgery, previously lost a 2021 paper in Science Translational Medicine after Elisabeth Bik and other commenters on PubPeer posted concerns about some of the images in the article. 

The newly retracted paper, “Phosphoglycerate Mutase 1 Activates DNA Damage Repair via Regulation of WIP1 Activity,” appeared in Cell Reports in 2020. It has been cited 25 times, according to Clarivate’s Web of Science. 

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How a sleuth’s email turned a correction into a retraction

Isabella Grumbach

On Sept. 2, 2021, a professor at the University of Iowa, in Iowa City, emailed a biochemistry journal asking to correct a paper she had published the previous year. An experiment had “unintentionally” been omitted from a figure, Isabella Grumbach explained, and a comparison of experimental groups contained “a minor error in the degree of statistical significance.” A correction ensued. 

But the problems with the article, “Inhibition of CaMKII in mitochondria preserves endothelial barrier function after irradiation,” appear to have been more deep-rooted than the email suggested. An anonymous commenter on PubPeer had first raised concerns about the article, which had appeared in Free Radical Biology and Medicine (FRBM), in July 2021, more than a year after it was published. The commenter claimed error bars between two figures were vastly different, even though they were meant to be related data points. 

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Cancer paper earns expression of concern nearly two years after investigation report is revealed

Carlo Croce

A Springer Nature journal has issued an expression of concern for a 16-year-old paper by Carlo Croce, the cancer researcher – and noted art collector – at The Ohio State University three years after the publication had received a correction for problematic images and roughly 20 months after the news division at Nature reported on a pair of institutional investigations into problems with Croce’s work. 

As we and others have reported, those investigations concluded Croce had not committed misconduct but had overlooked the misdeeds of others in his lab. 

Here’s the notice for the paper, “MicroRNA signatures of TRAIL resistance in human non-small cell lung cancer,” which Oncogene published in 2008:

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Journal takes 3 years to pull papers by researcher who committed misconduct

Samson Jacob

Nearly three years after a university investigation committee recommended retracting several papers by a cancer researcher found guilty of research misconduct, the journal Cancer Research has pulled three of the offending articles.

The journal also retracted a fourth paper by the researcher, Samson Jacob, a former emeritus professor at The Ohio State University, which had been flagged on PubPeer.

In 2021, the OSU committee reviewed dozens of allegations against Jacob’s work, and found 14 of them met at least one of two evidence standards for research misconduct, as we reported in 2022. The allegations mainly centered on figures that appeared to be spliced together from different experimental runs, which was not acknowledged in the studies – a concern the new retraction notices also mention. 

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Sociology journal’s entire editorial board resigns after Springer Nature appointed new leadership

The entire editorial board of a sociology journal has resigned after they say that the publisher, Springer Nature, installed new editors-in-chief without consulting the board — but Springer Nature says they tried unsuccessfully to engage the board on planning going back at least five years.

In December 2023, senior editors of the journal, Theory and Society, learned Springer Nature “had opted for a ‘completely different view’ of the journal going forward,” according to a message shared on a listserv for the American Sociological Association and published on the blog Scatterplot. The 10 senior editors subsequently resigned, they told their colleagues, but didn’t offer additional details. 

On January 4, the journal’s corresponding editors also resigned, according to a resignation letter shared with the sociology listserv. The corresponding editors cited Springer Nature’s decision to replace Janet Gouldner, the former executive editor (and widow of the journal’s founding editor, Alvin Gouldner), without consulting the rest of the editorial board. They wrote: 

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‘A travesty’: A researcher found guilty of misconduct by federal U.S. government responds

Hee-Jeong Im Sampen

“These findings are unjustified.”

That’s how a biologist at the Jesse Brown Veterans Affairs Medical Center in Chicago described the conclusions of a federal investigation that found she had faked images and inflated sample sizes in published papers and a grant application. The biologist, Hee-Jeong Im Sampen, has been banned from conducting VA research. 

Sampen, also a research professor at the University of Illinois-Chicago, said that “any errors that occurred involved discrete erroneously-placed figures or images” that “in no way undermine our basic conclusions and findings.”

Calling the episode a “long and hard battle for me,” Sampen sent us these comments:

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US VA scientist banned from agency research for faking data

Hee-Jeong Im Sampen

A research biologist at the Jesse Brown Veterans Affairs Medical Center in Chicago faked images and inflated sample sizes in published papers and a grant application, the federal agency has determined. 

Hee-Jeong Im Sampen, also a research professor of biomedical engineering at the University of Illinois, Chicago, “engaged in research misconduct by intentionally, knowingly and/or recklessly falsifying/fabricating data” in three published papers, an unpublished manuscript, a poster presentation, and a grant application for VA funding, according to a Federal Register notice

Sampen, who publishes under the name Hee-Jeong Im, is corresponding author on all of the published papers the VA identified. The articles, which also list an affiliation with Rush University Medical Center, are: 

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Nobel Prize winner Gregg Semenza tallies tenth retraction

Gregg Semenza

It’s Nobel Prize week, and the work behind mRNA COVID-19 vaccines has just earned the physiology or medicine prize. But this is Retraction Watch, so that’s not what this post is about.

A Nobel prize-winning researcher whose publications have come under scrutiny has retracted his 10th paper for issues with the data and images. 

Gregg Semenza, a professor of genetic medicine and director of the vascular program at Johns Hopkins’ Institute for Cell Engineering in Baltimore, shared the 2019 Nobel prize in physiology or medicine for “discoveries of how cells sense and adapt to oxygen availability.” 

The pseudonymous sleuth Claire Francis had flagged possibly duplicated or manipulated images in Semenza’s publications on PubPeer before 2019, and other sleuths posted more beginning in October 2020. 

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Former Stanford president retracts 1999 Cell paper

Marc Tessier-Lavigne

Marc Tessier-Lavigne, the former president of Stanford University who resigned following scrutiny of his published papers and an institutional research misconduct investigation, has retracted a third paper, this one from Cell

Last week, Tessier-Lavigne retracted two articles from Science that had been published in 2001. 

The Cell paper, A Ligand-Gated Association between Cytoplasmic Domains of UNC5 and DCC Family Receptors Converts Netrin-Induced Growth Cone Attraction to Repulsion, was published in 1999. It has been cited 577 times, according to Clarivate’s Web of Science. 

The retraction notice was posted Monday. It states:

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Exclusive: UCSF and VA found “pervasive” manipulation in lab of former center director

Rajvir Dahiya

Two institutional investigations that concluded in 2016 and 2019 found scientific misconduct in multiple publications from the lab of a leading urologist at the University of California, San Francisco, Retraction Watch has learned. 

The investigations could not determine who had manipulated the published images of experimental data, but the 2019 report concluded that Rajvir Dahiya, also director of the urology research center at the San Francisco Veterans Affairs Medical Center, “was senior/last author on all these publications and therefore responsible for the results.” Dahiya retired in 2020. 

The two investigation reports, which we obtained through a public records request, along with the reports from the preliminary inquiries preceding the investigations, recommend notifying the journals that published eight papers of the issues identified. Four have so far been retracted, one corrected, and two marked with expressions of concern. One of those expressions of concern was published last month. 

In comments to Retraction Watch, Dahiya blamed the findings that research misconduct occurred in his lab on the age of the papers. He said the VA destroyed notebooks with original data that had been stored in a central facility after the required data retention period had lapsed: 

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