Cancer specialist faked data in at least ten papers, VA and UCLA find

Alan Lichtenstein

A multiple myeloma specialist “recklessly“ falsified data in at least 10 published articles, according to a joint investigation by the University of California, Los Angeles David Geffen School of Medicine and Veterans Affairs Greater Los Angeles Healthcare System. 

The institutions found Alan Lichtenstein, a former staff physician at the VA, committed research misconduct by reusing images “to falsely represent the results” related to 26 pairs of experiments, according to a notice published in the Federal Register. 

At least one of the sets of images in each of the pairs “is inaccurate,” the notice stated. The institutions found Lichtenstein had falsified data in “at least ten” of the 13 articles in which the images appeared, perhaps because the investigators could not determine which images, if any, were original. 

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Penn State barred embattled professor from doing research

Deborah Kelly

The Pennsylvania State University in May blocked a prominent professor at the school from doing research and making presentations on its behalf, Retraction Watch has learned. 

The professor, Deborah Kelly, has faced mounting scrutiny over her work since a researcher in the United Kingdom noticed apparent data manipulation in a now-retracted article she published in 2017. Kelly earned her third retraction last week following a university probe that found “serious data integrity concerns” in another paper, as we reported at the time. 

In comments she made via her legal counsel for that story, Kelly, a biomedical engineer and an expert in electron microscopy, told us:

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Nobel prize-winner tallies two more retractions, bringing total to 13

Gregg Semenza

A Nobel prize-winning genetics researcher has retracted two more papers, bringing his total to 13. 

Gregg Semenza, a professor of genetic medicine and director of the vascular program at Johns Hopkins’ Institute for Cell Engineering in Baltimore, shared the 2019 Nobel prize in physiology or medicine for “discoveries of how cells sense and adapt to oxygen availability.” 

Since pseudonymous sleuth Claire Francis and others began using PubPeer to point out potential duplicated or manipulated images in Semenza’s work in 2019, the researcher has retracted 12 papers. A previous retraction from 2011 for a paper co-authored with Naoki Mori – who with 31 retractions sits at No. 25 on our leaderboard – brings the total to 13. 

Continue reading Nobel prize-winner tallies two more retractions, bringing total to 13

Penn State prof earns second retraction, faces third following university probe

Deborah Kelly

A professor of biomedical engineering at the Pennsylvania State University today lost a government-funded study in Science Advances, marking her second retraction. 

The researcher, Deborah Kelly, is also facing retraction of a paper in Current Opinion in Structural Biology after a review undertaken by her institution found “serious data integrity concerns” in the work, according to emails obtained by Retraction Watch. Kelly has hired a lawyer to fight the retraction, apparently without success. (Update on Sept. 12: The paper has now been retracted.)

Today’s retraction of “Structural analysis of BRCA1 reveals modification hotspot” cites “unresolved concerns in the integrity of the data presented,” including what appears to be alterations of cryogenic electron microscopy (cryo-EM) maps using an “eraser tool.” The study was funded in part through a National Institutes of Health (NIH) grant for US$353,386 to Kelly.

In a statement to Retraction Watch sent via her legal counsel, Kelly stood by her work. 

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Faked heart papers retracted following Ohio State investigation

A physiology journal has retracted two papers after an institutional investigation found a heart researcher falsified data and figures in the articles.

A committee at the Ohio State University found Govindasamy Ilangovan, an associate professor of cardiovascular medicine at the school, falsified figures and reused data, according to the retraction notices published in Heart and Circulatory Physiology, a journal of the American Physiological Society. 

The two papers, “Heat shock protects cardiac cells from doxorubicin-induced toxicity by activating p38 MAPK and phosphorylation of small heat shock protein 27,” and “HSP27 regulates p53 transcriptional activity in doxorubicin-treated fibroblasts and cardiac H9c2 cells: p21 upregulation and G2/M phase cell cycle arrest,” first appeared nearly 20 years ago. They have received 132 citations in total, according to Clarivate’s Web of Science.

The notices detail how Ilangovan repurposed and relabelled Western blots from both published and unpublished works. One of the figures also was “inaccurate” due to “addition of false bands” in a Western blot, but the notice did not explicitly attribute the problems with the figure to Ilangovan.

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Brain tumor researchers lose second paper as UCSF investigates

Russell Pieper

A research group at the University of California, San Francisco, under investigation for potential misconduct has had a second paper retracted.

The group, led by Russell O. Pieper, director of basic science at the UCSF Brain Tumor Center and vice-chairman of the UCSF Department of Neurological Surgery, previously lost a 2021 paper in Science Translational Medicine after Elisabeth Bik and other commenters on PubPeer posted concerns about some of the images in the article. 

The newly retracted paper, “Phosphoglycerate Mutase 1 Activates DNA Damage Repair via Regulation of WIP1 Activity,” appeared in Cell Reports in 2020. It has been cited 25 times, according to Clarivate’s Web of Science. 

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How a sleuth’s email turned a correction into a retraction

Isabella Grumbach

On Sept. 2, 2021, a professor at the University of Iowa, in Iowa City, emailed a biochemistry journal asking to correct a paper she had published the previous year. An experiment had “unintentionally” been omitted from a figure, Isabella Grumbach explained, and a comparison of experimental groups contained “a minor error in the degree of statistical significance.” A correction ensued. 

But the problems with the article, “Inhibition of CaMKII in mitochondria preserves endothelial barrier function after irradiation,” appear to have been more deep-rooted than the email suggested. An anonymous commenter on PubPeer had first raised concerns about the article, which had appeared in Free Radical Biology and Medicine (FRBM), in July 2021, more than a year after it was published. The commenter claimed error bars between two figures were vastly different, even though they were meant to be related data points. 

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Cancer paper earns expression of concern nearly two years after investigation report is revealed

Carlo Croce

A Springer Nature journal has issued an expression of concern for a 16-year-old paper by Carlo Croce, the cancer researcher – and noted art collector – at The Ohio State University three years after the publication had received a correction for problematic images and roughly 20 months after the news division at Nature reported on a pair of institutional investigations into problems with Croce’s work. 

As we and others have reported, those investigations concluded Croce had not committed misconduct but had overlooked the misdeeds of others in his lab. 

Here’s the notice for the paper, “MicroRNA signatures of TRAIL resistance in human non-small cell lung cancer,” which Oncogene published in 2008:

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Journal takes 3 years to pull papers by researcher who committed misconduct

Samson Jacob

Nearly three years after a university investigation committee recommended retracting several papers by a cancer researcher found guilty of research misconduct, the journal Cancer Research has pulled three of the offending articles.

The journal also retracted a fourth paper by the researcher, Samson Jacob, a former emeritus professor at The Ohio State University, which had been flagged on PubPeer.

In 2021, the OSU committee reviewed dozens of allegations against Jacob’s work, and found 14 of them met at least one of two evidence standards for research misconduct, as we reported in 2022. The allegations mainly centered on figures that appeared to be spliced together from different experimental runs, which was not acknowledged in the studies – a concern the new retraction notices also mention. 

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Sociology journal’s entire editorial board resigns after Springer Nature appointed new leadership

The entire editorial board of a sociology journal has resigned after they say that the publisher, Springer Nature, installed new editors-in-chief without consulting the board — but Springer Nature says they tried unsuccessfully to engage the board on planning going back at least five years.

In December 2023, senior editors of the journal, Theory and Society, learned Springer Nature “had opted for a ‘completely different view’ of the journal going forward,” according to a message shared on a listserv for the American Sociological Association and published on the blog Scatterplot. The 10 senior editors subsequently resigned, they told their colleagues, but didn’t offer additional details. 

On January 4, the journal’s corresponding editors also resigned, according to a resignation letter shared with the sociology listserv. The corresponding editors cited Springer Nature’s decision to replace Janet Gouldner, the former executive editor (and widow of the journal’s founding editor, Alvin Gouldner), without consulting the rest of the editorial board. They wrote: 

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