Archive for the ‘ori investigations’ Category
Journals have retracted three out of the four papers flagged by the Office of Research Integrity during its investigation of a University of Oregon neuroscience student, David Anderson.
Last month, when we first reported on the case, Anderson told us that he “made an error in judgment,” and took “full responsibility.” Two of the retraction notes say that Anderson “knowingly falsified data,” and cited the Office of Research Integrity case summary.
All three papers focus on memory.
The note for the first retraction, from the Journal of Experimental Psychology: Human Perception and Performance, reveals exactly how Anderson falsified data in the paper. It’s paywalled — tsk, tsk — but printed here in full:
Read the rest of this entry »
A former graduate student at the University of California, San Francisco “knowingly falsified and/or fabricated” data in two published papers, according to the Office of Research Integrity.
According to a case summary published this morning, Peter Littlefield was working on his PhD, studying the ways that cells respond to external signals, when he published the two problematic papers. He is the first author on the papers; Natalia Jura, whose lab he worked in, is the last on both.
The report’s findings are based on, among other sources, “the respondent’s admission.”
The first paper, “Structural analysis of the EGFR/HER3 heterodimer reveals the molecular basis for activating HER3 mutations” was published in Science Signaling and has been cited twice, according to Thomson Scientific’s Web of Knowledge.
Three figures in the paper are problematic, says the ORI summary:
A former graduate student at Wake Forest School of Medicine “presented falsified and/or fabricated data” in a government-funded drug study, according to findings released by the U.S. Office of Research Integrity earlier today.
The report was released in the wake of an investigation conducted by the university and the ORI. Investigators found that although Brandi Blaylock recorded responses of a dozen laboratory monkeys after giving them anti-abuse drugs, she hadn’t given them the compounds “per protocol.”
Blaylock then presented the data at “two poster presentations, several laboratory meetings, and progress reports.”
Some of her research was supported by a grant from the National Institute of Drug Abuse, “Dopamine D2 Receptors In Primate Models of Cocaine Abuse,” which examined the effects of novel dopamine D3 receptor compounds on drug addiction on monkeys.
However, according to the report, Blaylock presented the falsified responses from a dozen monkeys: Read the rest of this entry »
Have you ever wondered what could happen if you’re accused of misconduct and face official proceedings? We are pleased to present a guest post from Callan Stein, a lawyer who represents U.S. researchers in misconduct cases, who describes some nuances many may not realize about these situations.
Most researchers know that being accused of research misconduct is a very serious matter. When research misconduct allegations are made, institutions embark upon lengthy, multi-staged inquiry and investigation processes as required by federal law. The federal government’s Office of Research Integrity (“ORI”) – part of the Department of Health and Human Services (HHS) – oversees those institutional findings and imposes potentially career-threatening punishments on those found guilty. While researchers generally understand the basics of how a research misconduct case unfolds, many are unaware of the nuances that bear greatly on the outcome. What follows are brief descriptions of eight such nuances of which every researcher should be aware.
- While “honest error” exempts researchers from misconduct, it is very hard to prove.
Retractions have been published for four papers authored by former Wayne State University professor, Teresita L. Briones, after an April ORI report found evidence of misconduct in the articles.
Investigators found that Briones had “intentionally, knowingly, and recklessly engaged in research misconduct by falsifying and/or fabricating data.” They flagged five papers and three grant applications that contained false data.
As a result of their findings, four out of the five papers have been retracted, and the editors of the remaining journal say they are looking into the last paper.
A graduate student at the University of Oregon in Eugene has admitted to faking data that appeared in four published papers in the field of visual working memory, according to the Office of Research Integrity.
Anderson told Retraction Watch that the misconduct stemmed from “an error in judgment”:
A former postdoctoral fellow at Penn State University faked numerous data and analyses in a manuscript submitted to Molecular Cancer Research, according to the Office of Research Integrity (ORI).
In a notice released today, the ORI found Julie Massè: Read the rest of this entry »
An HIV researcher has admitted to faking data in a published paper, a manuscript, and two grant applications, according to a notice released today by the the Office of Research Integrity (ORI).
Former postdoc Julia Bitzegeio faked data in a 2013 paper, published in the Journal of Virology, about how HIV adapts to interferon. In the paper, “the manipulation was really minor,” Theodora Hatziioannou, principal investigator of the lab at the Aaron Diamond AIDS Research Center (ADARC) in New York City where Bitzegeio worked, told Retraction Watch. “She just made cosmetic changes.”
The paper will be corrected, Hatziioannou said. Bitzegeio has left her lab, and her future is somewhat less clear:
A researcher who confessed to spiking rabbit blood samples to make the results of an HIV vaccine experiment look better has been sentenced to 57 months of prison time, according to The Des Moines Register.
Dong-Pyou Han has also been ordered to repay more than $7 million to the U.S. National Institutes of Health, and will have three years of supervised release following his prison term.
In December, 2013, the U.S. Office of Research Integrity announced that Han, formerly at Iowa State University (ISU), had faked his results to make an HIV vaccine look more powerful. The faulty data made their way into seven national and international symposia between 2010 and 2012 (resulting in a retracted poster in 2014), along with three grant applications and multiple progress reports. Han agreed to a three-year research ban, and resigned from ISU in October the following year.
The NIH never sent the final $1.38 million grant payment of more than $10 million awarded to Han’s boss, Michael Cho, and ISU returned nearly $500,000 it had received for Han’s salary and other costs.
However, Read the rest of this entry »
Two papers about the molecular underpinnings of lung damage are being retracted following an investigation at Oita University in Japan, which revealed that images from both papers had been used to depict “different experimental conditions” in a third paper (which has not been retracted).
It’s not clear which of the authors were the subject of the investigation. The two retracted papers, “Nafamostat mesilate inhibits the expression of HMGB1 in lipopolysaccharide-induced acute lung injury” in the Journal of Anesthesia and “Coexpression of HSP47 Gene and Type I and Type III Collagen Genes in LPS-Induced Pulmonary Fibrosis in Rats” in Lung, both originally published in 2007, share the same first author — Satoshi Hagiwara, whose affiliation is listed as the Department of Brain and Nerve Science, Anesthesiology, Oita University Faculty of Medicine. The papers have been cited 13 times and 12 times, respectively, according to Thomson Scientific’s Web of Knowledge. Hagiwara is also the first author on the third paper that contains the duplicated images.
The first retraction notice reads: