Archive for the ‘ori investigations’ Category
One Friday in January, graduate student Meredyth Forbes was reviewing material for her dissertation with her mentor when she decided to make a confession.
She “burst out with a statement that some of the data was fabricated,” said Edward Burns, research integrity officer at the Albert Einstein College of Medicine, where Forbes worked. It was, Burns told Retraction Watch: Read the rest of this entry »
The retractions come as part of a backstory of pulled papers authored by psychologist Edward Awh and his former graduate student David Anderson when he was based at the University of Oregon in Eugene. The pair retracted four papers last year after Anderson admitted to misconduct during an investigation by the U.S. Office of Research Integrity (and spoke to us about it last July). This led Awh — now based at the University of Chicago in Illinois — to take a second look at the other publications he’d co-authored with Anderson; earlier this year, Awh retracted two others, and informed us more would be coming, including the two most recent publications.
In May of last year, Stephanie Watkins, who now works at Loyola Medicine, earned two retractions, which mention a review by an investigation committee at the National Institutes of Health. Two of the new notes, published in Cancer Research, mention the review as well, and cite data falsification in a figure as the reason for retraction. Watkins is the only author that did not agree to those retractions.
There may be more changes to the literature — an editor at another cancer journal told us the journal is awaiting a decision from the Office of Research Integrity before deciding what to do with a paper by Watkins, given that she does not agree with the misconduct charges.
We’ll start with a retraction note from Cancer Research:
Authors have retracted two papers about visual perception and working memory from the Journal of Cognitive Neuroscience, after the first author admitted to falsifying or fabricating data in four other papers.
The authors have requested another two retractions, as well, which will bring the total for Edward Awh and his former graduate student David Anderson to nine retractions. (Earlier in 2015, they lost a paper due to an error in the analytic code, which Awh told us was unrelated to the misconduct.)
The retraction notice attached to both articles cites a 2015 settlement agreement between the Office of Research Integrity and first author Anderson (the “respondent”), who admitted to misconduct while working as a graduate student in the lab of Awh at the University of Oregon in Eugene. Since then, “additional problems” were discovered in the newly retracted articles, such as removed data points.
A paper flagged in an Office of Research Integrity notice more than one year ago has finally been retracted. According to the notice, the paper includes images manipulated by author H. Rosie Xing, a former University of Chicago cancer researcher.
The main conclusions of the paper are affected by the ORI finding, according to the retraction note from Molecular Cancer Therapeutics. But otherwise, the note contains information that was available in the ORI finding, published in December 2014.
“Pharmacologic Inactivation of Kinase Suppressor of Ras1 Sensitizes Epidermal Growth Factor Receptor and Oncogenic Ras-Dependent Tumors to Ionizing Radiation Treatment” has been cited seven times, according to Thomson Scientific’s Web of Knowledge — twice since the ORI finding came out.
The retraction note explains which images were affected by the manipulation:
The Office of Research Integrity’s findings are based on an inquiry at Virginia Commonwealth University, where Girija Dasmahapatra worked until July of this year, investigating possible therapies for cancer. The misconduct affected research funded by three grants from the National Institutes of Health. Steven Grant, a researcher at VCU, is the principal investigator on the grants, each of which total over $2 million in funding. All of the 11 affected papers will be corrected or retracted, according to the ORI notice.
Two of the papers containing “falsified and/or fabricated” data — a study on an experimental combination of drugs for blood cancer and one on chemotherapies for rare forms of lymphoma — were covered in press releases by VCU.
According to the notice in the Federal Register:
The director of the Research Integrity & Compliance Review Office at Colorado State University (CSU) is the new head of the U.S. Office of Research Integrity, taking over a position that has been vacant for more than a year and a half.
The Office of Research Integrity report found that Maria C.P. Geraedts manipulated bar graphs in the papers to “produce the desired result.” Both have been retracted. Geraedts left academia in 2014, and is now a science writer.
We reported on one retraction in July, “Gustatory stimuli representing different perceptual qualities elicit distinct patterns of neuropeptide secretion from taste buds,” published in The Journal of Neuroscience.
The other, “Transformation of postingestive glucose responses after deletion of sweet taste receptor subunits or gastric bypass surgery,” published in 2012 in the American Journal of Physiology Endocrinology and Metabolism, was retracted in September. Here’s the note, which cites the university’s investigation: Read the rest of this entry »
A federal investigation into a paper on prostate cancer has now led to a retraction. In an unusual twist, it happened following a request from the animal rights group People for the Ethical Treatment of Animals (PETA).
In January, the Office of Research Integrity reported that corresponding author Dong Xiao “intentionally fabricated data” in an Oncotarget study of how a steroid inhibits the growth of prostate cancer. Xiao, a former cancer researcher at the University of Pittsburgh, claimed that he had tumor data from more mice than he did, and falsified several figures.
In July, after no sign of the retraction, a researcher at PETA followed up with the journal, Oncotarget, on behalf of the organization “and our more than 3 million members and supporters to request the immediate retraction.”
Last month, they received a reply from the publisher, which they forwarded to us:
A retired obstetrics and gynecology professor under federal investigation for misconduct has notched his ninth retraction.
The latest retraction stems from an investigation by the University of Florida, where Nasser Chegini worked until 2012, which found fabricated data in three figures in a paper on the muscle cells that line the uterus.
The paper, “Differential expression of microRNAs in myometrium and leiomyomas and regulation by ovarian steroids,” was published in The Journal of Cellular and Molecular Medicine. It’s been cited 74 times, according to Thomson Scientific’s Web of Knowledge.
Here’s the note: