Here’s the notice for “Refining siRNA in vivo transfection: Silencing SPHK1 reveals its key role in C5a-induced inflammation in vivo,” by Alirio Melendez and colleagues in The International Journal of Biochemistry & Cell Biology:
This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy).
This article has been retracted at the request of the Editor-in-Chief.
Data presented in this paper have been manipulated digitally. Figures shown in this article have been replicated in other papers depicting different experimental conditions. The other papers are:
Puneet P, Yap CT, Wong L, Lam Y, Koh DR, Moochhala S, Pfeilschifter J, Huwiler A, Melendez AJ. SphK1 regulates proinflammatory responses associated with endotoxin and polymicrobial sepsis. Science 2010;328:1290–4.
The study has been cited 18 times, according to Thomson Scientific’s Web of Knowledge.
The Science paper to which the notice refers has already been subject to an Expression of Concern and a correction.