Retraction Watch

Tracking retractions as a window into the scientific process

Archive for the ‘molecular biology’ Category

Two more retractions for stem cell researcher appealing her dismissal

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Susana Gonzalez

Susana Gonzalez, a rising star in stem cell research, has had a rough year.

In addition to being fired from her former research institute (which she is now appealing), one of her grants (totaling nearly 2 million Euros) was suspended. Most recently, she has received two new retractions in Nature Communications over figure duplications and missing raw data. By our count, she has a total of three retractions.

Both of the new notices say the papers contained figures duplicated in other papers by Gonzalez, and neither includes Gonzalez among the list of co-authors who agreed to the retraction.

Gonzalez was dismissed from her position at the National Center for Cardiovascular Research (CNIC) in Spain last February over allegations of misconduct. According to the head of basic research at CNIC, Gonzalez is still embroiled in a legal battle with the Center over her dismissal. Vicente Andrés could not go into detail because of the ongoing litigation, but he told us: Read the rest of this entry »

15-year old paper pulled for image problems

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A group of researchers in France has been forced to retract their 2002 article in the Journal of Virology after learning that the paper was marred by multiple image problems.

The paper, “P0 of Beet Western Yellows Virus Is a Suppressor of Posttranscriptional Gene Silencing,” came from the lab of Veronique Ziegler-Graff, a plant biologist at the University Louis Pasteur, in Strasbourg. The authors attribute some of the image problems to “genuine mounting mistakes,” and have repeated the experiments to confirm the conclusion, as have other labs. However, the researchers couldn’t find all the original data from the 2002 paper.

Although the retraction statement points the finger at the first author, Sebastien Pfeffer, the list of contributors includes Patrice Dunoyer, a frequent collaborator of Olivier Voinnet, a high-profile plant biologist whose work has come under intense scrutiny.

According to the lengthy notice:
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“Knowledgeable informant” outs researchers for falsifying data

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A pathology journal has retracted a 2015 paper from researchers in China after concluding the authors had falsified and copied some of the data and text.

According to the notice, a “knowledgeable informant” told the journal about the overlap and “fraudulent” aspects of the paper, which the editors were able to confirm. The journal retracted the paper last month.

Here’s the retraction notice for “Genistein attenuates glucocorticoid-induced bone deleterious effects through regulation Eph/ephrin expression in aged mice:”

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3rd retraction appears for fired Pfizer breast cancer researcher

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Pfizer has retracted a paper by a former employee who was fired after the company discovered she had been doctoring data.

The retraction, in Molecular Cancer Research, is the third of five papers Pfizer asked to retract, after an investigation discovered they contained duplicated images. The papers have been discussed on PubPeer, which is also mentioned in the latest retraction notice.

As a result of the investigation, Pfizer terminated the employment of Min-Jean Yin, the last author on the newly retracted paper.

According to the notice, Yin and five of her co-authors agreed to the retraction:

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Unexplained abnormalities in stem cells prompt Columbia researchers to pull diabetes paper

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Researchers at Columbia University have retracted a 2013 paper in The Journal of Clinical Investigation, after uncovering abnormalities in the stem cell lines that undermined the conclusions in the paper.

Last year, corresponding author Dieter Egli discovered he could not reproduce key data in the 2013 paper because almost all the cell lines first author Haiqing Hua used contained abnormalities, casting doubt on the overall findings. When Egli reached out to Hua for answers, Hua could not explain the abnormalities. As a result, Hua and Egli agreed the paper should be retracted.

Since some of the details of how the paper ended up relying on abnormal cells remain unclear, the university confirmed to us that it is investigating the matter.

Here’s the retraction notice for “iPSC-derived β cells model diabetes due to glucokinase deficiency,” cited 42 times: Read the rest of this entry »

Cancer biologist stops research as his retraction count rises to 13

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Anil Jaiswal

A cancer biologist based at the University of Maryland is transitioning out of research, as a journal has retracted three more of his papers.

Anil Jaiswal has now lost 13 papers, including, as we reported on February 6, six retractions issued earlier this month.

The Baltimore Sun reported this week that Jaiswal would no longer be conducting research at the University of Maryland School of Medicine, which we confirmed from a spokesperson:

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Authors pull virus replication paper after they cannot replicate results

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Researchers in China have retracted a 2016 paper exploring the replication behaviors of a retrovirus, after discovering that the key results could not be reproduced — possibly because their cell cultures had been contaminated.

The authors also cite a disagreement with a colleague, who they say contributed to the work but does not want to be listed as an author.

Here’s the retraction notice for “Nuclear import of prototype foamy virus transactivator Bel1 is mediated by KPNA1, KPNA6 and KPNA7,” published in the International Journal of Molecular Medicine: Read the rest of this entry »

Journal pulls paper with missing data, citing inquiry and legal proceedings

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A journal has retracted a 2012 paper after the last author was unable to provide material to support the results presented in multiple figures.

The lack of supporting data came out during “an internal inquiry and subsequent legal proceedings,” according to the notice, issued by Cell Cycle.

The last author on the paper is Susana Gonzalez, who was dismissed from her position at the National Center for Cardiovascular Research (CNIC) in Spain last year.

Here’s the full notice:

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Students withdraw report of private stem cell retreat

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Master’s students have retracted a review of an internal meeting of stem cell researchers because it contained confidential information.

According to the Managing Director of the society, Stem Cell Network North Rhine Westphalia (NRW), the event was not open to the public, and the authors had not contacted either the society or the scientists they cited before publishing the report.

Here’s the retraction notice for “A Report on the Internal Retreat Meeting of the Stem Cell Network North Rhine Westphalia,” published online in Molecular Biotechnology on October 31 and retracted shortly after on December 14: Read the rest of this entry »

Columbia University probe prompts retraction of cardiovascular paper

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A journal has retracted a 2011 study at the request of Columbia University.

According to Jeanine D’Armiento, the study’s last author, the newly retracted paper in Clinical Science contained a figure from a Journal of Hypertension paper published by the same authors earlier that year. 

First and corresponding author Joseph George told Retraction Watch the error was unintentional. A Columbia spokesperson sent us this statement: Read the rest of this entry »