Retraction Watch

Tracking retractions as a window into the scientific process

Archive for the ‘cancer biology’ Category

3rd retraction appears for fired Pfizer breast cancer researcher

without comments

Pfizer has retracted a paper by a former employee who was fired after the company discovered she had been doctoring data.

The retraction, in Molecular Cancer Research, is the third of five papers Pfizer asked to retract, after an investigation discovered they contained duplicated images. The papers have been discussed on PubPeer, which is also mentioned in the latest retraction notice.

As a result of the investigation, Pfizer terminated the employment of Min-Jean Yin, the last author on the newly retracted paper.

According to the notice, Yin and five of her co-authors agreed to the retraction:

Read the rest of this entry »

Cancer biologist stops research as his retraction count rises to 13

with 16 comments

Anil Jaiswal

A cancer biologist based at the University of Maryland is transitioning out of research, as a journal has retracted three more of his papers.

Anil Jaiswal has now lost 13 papers, including, as we reported on February 6, six retractions issued earlier this month.

The Baltimore Sun reported this week that Jaiswal would no longer be conducting research at the University of Maryland School of Medicine, which we confirmed from a spokesperson:

Read the rest of this entry »

Cancer researcher logs 6 retractions, bringing total to 10

with 24 comments

Anil Jaiswal

A journal has retracted six papers by a cancer researcher at the University of Maryland in Baltimore, bringing his total to 10.

The retractions cite an investigation by the university, and detail problems ranging from duplicated images, to tweaking an image to conceal particular bands, to including unreliable data.

Three of the papers had already been flagged by the journal with expressions of concern. The last author on all the papers is Anil Jaiswal, a professor in the pharmacology department. He has issued four previous retractions.

Bruce Jarrell, the Chief Academic and Research Officer and Senior Vice President at the University of Maryland, told us at least two more retractions are forthcoming:

Read the rest of this entry »

“We made big mistakes:” Gastric paper pulled with unusual notice

without comments

Sometimes we come across a real head-scratcher.

That happened this week, when we saw a retraction notice for a 2015 paper on gastric cancer in the International Journal of Clinical and Experimental Medicine, which only says the authors “made big mistakes” and contains two fairly significant typos.

Although there’s no sign of a retraction on PubMed, the table of contents for the latest issue of the journal lists the retraction — but includes no hyperlink to the notice. The only way to see it is via a Web cached version. Here’s the text:

Read the rest of this entry »

What turned a cancer researcher into a literature watchdog?

without comments

Jennifer Byrne

Sometime in the middle of 2015, Jennifer Byrne, professor of molecular oncology at the University of Sydney, began her journey from cancer researcher to a scientific literature sleuth, seeking out potentially problematic papers.

The first step was when she noticed several papers that contained a mistake in a DNA construct which, she believed, meant the papers were not testing the gene in question, associated with multiple cancer types.  She started a writing campaign to the journal editors and researchers, with mixed success. But less than two years later, two of the five papers she flagged have already been retracted.

When asked why she spent time away from bench research to examine this issue, Byrne told us:  Read the rest of this entry »

At last, cancer reproducibility project releases some results — and they’re mixed

without comments

Nearly five years ago, researchers suggested that the vast majority of preclinical cancer research wouldn’t hold up to follow-up experiments, delaying much needed treatments for patients. In a series of articles publishing tomorrow morning, eLife has released the results of the first five attempts to replicate experiments in cancer biology — and the results are decidedly mixed.

As our co-founders Adam Marcus and Ivan Oransky write in STAT, the overall take-home message was that two studies generated findings similar to the original, one did not replicate the original, and two others were inconclusive.

They quote Brian Nosek, a psychologist at the University of Virginia, in Charlottesville, who runs the Center for Open Science, who has been leading the replication effort in his own field:

Read the rest of this entry »

Written by Alison McCook

January 18th, 2017 at 1:53 pm

Breast cancer studies by fired Pfizer employee retracted

without comments

Last year, Pfizer fired one of its scientists following an investigation that ended with requests for retraction of five of her studies. Now, two of the five papers, which were first flagged on PubPeer, have been retracted.

One notice cites the Pfizer investigation, which found that cancer researcher Min-Jean Yin had included duplicated images in all five papers. Yin is the last author on both retracted papers.

Here’s the first notice from Clinical Cancer Research, which says most or all of the questioned images appear to be duplicates, and Pfizer — who sponsored the study and requested the retraction — can’t find the originals:
Read the rest of this entry »

Journal retracts gastric cancer study with multiple duplications, authors MIA

with 3 comments

An oncology journal has decided to retract a 2012 paper on gastric cancer after discovering duplicated data in multiple figures.

According to the retraction notice, the journal’s editorial board received a tip from a reader regarding the potential figure issues. Oncology Reports launched an investigation, which confirmed the allegations. The authors failed to respond to the journal’s multiple requests for more information.

Here’s the retraction notice: Read the rest of this entry »

Cancer researcher in Germany loses multiple papers after misconduct finding

with one comment

A pathology journal is retracting two papers after an investigation at the last author’s institution in Germany found evidence of scientific misconduct.

The notice for both papers cites an investigation involving Regine Schneider-Stock, who studies cancer biology at the Friedrich Alexander-University Erlangen-Nuremberg (FAU). Meanwhile, another 2005 paper that lists Schneider-Stock as the first author was retracted in October, noting evidence of image manipulation.

The most recent retractions, from the American Journal of Pathology, note that FAU declined to provide the journal with details of its investigation beyond a prepared statement:

Read the rest of this entry »

Journal cleans the house by retracting 6 cancer papers for plagiarism

with 3 comments

Following an investigation, a genetics journal has pulled six cancer papers published this year for plagiarizing from other sources.

According to an excerpt from the retraction notice in Genetics and Molecular Research, the journal has “strong reason to believe that the peer review process was [a] failure,” and has alerted the authors’ institutions.

The notice announcing the retraction of all six papers begins: Read the rest of this entry »