Archive for the ‘NAS’ Category
Scientists at Duke and the National Institutes of Health have retracted a PNAS paper on asthma treatment after realizing the data from two sources didn’t match, and “most primary data” from several experiments were missing.
The mix up seems to have come from the pulmonary function laboratory that tested how well asthmatic patients’ lungs were functioning on an experimental anti-inflammatory therapy. As the authors say in the retraction note: Read the rest of this entry »
The paper tries to explain how Epstein-Barr virus blocks the immune system’s attempts to destroy it. According to the notice, the three “nonexperimentalist authors” – identified in the paper as two P.I.’s from University of Texas at Austin and one from the University of California, San Francisco – didn’t know the figures “were not reflective of original Northern blot and immunoblot data.”
That leaves UT Austin PhD student Jennifer Cox under the bus. Her LinkedIn says she pursued a PhD from 2010-2015, though it’s unclear if she’s received a degree. Cox’s name is at the top of P.I. Christopher Sullivan’s list of past lab members, and she’s the only one on the page whose name doesn’t hyperlink to additional information, such as a contact.
The authors of a 2007 PNAS paper that provided molecular details for how calorie restriction may act on Sir2 enzymes to extend life are now retracting their research after discovering a figure was compromised by “several unintentional anomalies in the background image.”
According to study author David W. Piston at Vanderbilt University, first author Qinghong Zhang cut and pasted images together to beautify a figure showing how a form of sugar affects the expression of SIRT1, the mammalian version of the Sir2 enzyme: Read the rest of this entry »