Retraction Watch

Tracking retractions as a window into the scientific process

Archive for the ‘molecular endocrinology’ Category

Researcher whose PhD was revoked is no longer at Harvard lab

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mend.2016.30.issue-8.coverA research fellow at Harvard Medical School whose PhD was revoked last month is no longer working in his former lab, Retraction Watch has learned. 

An archived version of the lab site for Alfred Goldberg from December, 2015, lists Sudarsanareddy Lokireddy as a postdoctoral fellow; however, Goldberg’s current lab site doesn’t include Lokireddy as a lab member.

We contacted Goldberg’s lab, and he was unavailable for comment. We were told all of his lab members are on the current website.

Lokireddy has also logged his sixth retraction. But this case isn’t as straightforward as it seems.

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Harvard researcher’s PhD revoked, former group earns three more retractions

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Journal of Biological ChemistryA research fellow at Harvard has lost his PhD from a university in Singapore after being found guilty of falsifying data, and his former group leader’s contract has been terminated by his institution.

But that’s not the whole story. This tangled mess involves not only the Harvard researcher, Sudarsanareddy Lokireddy, and his former boss, Ravi Kambadur at the Nanyang Technological University (NTU) in Singapore, but an as-yet unnamed colleague of theirs who, we’re told, has admitted making up data in three papers, on which Lokireddy and Kambadur are co-authors. Bear with us as we walk you through this tale.

Two of those papers have been retracted by The Journal of Biological Chemistry (JBC); one in Molecular Endocrinology has yet to be pulled. Kambadur, who held joint appointments at the NTU and the Agency for Science, Research and Technology (A*STAR) in Singapore, has now had his contract terminated at both institutions.  Read the rest of this entry »

Singapore investigation leads to another retraction, correction for Harvard research fellow

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After an investigation found evidence of misconduct, a biologist has issued a third retraction.

Sudarsanareddy Lokireddy — now a research fellow at Harvard Medical School — “admitted falsification,” a Research Integrity Officer at Nanyang Technological University in Singapore told us in December. According to The Scientist, another journal has also published a correction that the authors had requested earlier.

The newly retracted paper is “Myostatin is a novel tumoral factor that induces cancer cachexia,” published in Biochemical Journal and cited 40 times, according to Thomson Reuters Web of Science. Here’s the retraction note:

Second of 3 retractions appears for biologist, the result of “a substantial number of falsifications”

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Screen Shot 2016-01-13 at 10.19.01 AMA cell biologist who falsifed Western blots has notched a second retraction, with one more expected after a investigation at Nanyang Technological University in Singapore.

First author Sudarsanareddy Lokireddy, now apparently a research fellow at Harvard, did not agree to the retraction, the result of “a substantial number of falsifications.”

In December, we covered the results of the NTU investigation, where Lokireddy used to work. During that investigation, he admitted to falsifying data, Research Integrity Officer Tony Mayer told us. The end result: three retractions.

One of those papers was retracted by Cell Metabolism in December. The second paper, published in Molecular Endocrinology, has been cited 52 times, according to Thomson Scientific’s Web of Knowledge. The retraction note explains which figures were falsified:

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Singapore investigation leads to two retractions, two more on the way

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cov150hAuthors have retracted papers from Cell Metabolism and the Journal of Biological Chemistry after an investigation in Singapore found issues, including falsified data. The investigation is ongoing, and two additional retractions, along with two corrections, are on the horizon.

The investigation looked into papers by first authors Sudarsanareddy Lokireddy, now a postdoc at Harvard, and Sandhya Sriram, a postdoc at the Agency for Science, Technology and Research in Singapore. Led by the Nanyang Technological University in Singapore, where some of the work was done, the investigation concluded that there were issues with six papers on which either Sriram or Lokireddy was first author.

All authors but Lokireddy have agreed to retractions or corrections. Ravi Kambadur of NTU, and Mridula Sharma at the National University of Singapore, are the last two authors on all the papers.

According to a notice from the NTU, the “investigation found a number of instances of alterations to data” in three papers on which Lokireddy is first author. One of those was retracted December 1 by Cell Metabolism: Read the rest of this entry »

Cancer researcher has correction upgraded to retraction

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mol endo coverRakesh Kumar, a researcher with six recent corrections and one retraction, has had one of those corrections upgraded to a retraction.

Here’s the unhelpful notice, from Molecular Endocrinology: Read the rest of this entry »

Two papers to be retracted after ORI finds misconduct by Boston University cancer researcher

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courtesy Nature Publishing Group

The U.S. Department of Health and Human Services’ Office of Research Integrity (ORI) has found that a Boston University cancer researcher made up experiments reported in two papers funded by National Cancer Institute and National Institutes of Health grants. According to the ORI notice:

Sheng Wang, PhD, Boston University School of Medicine Cancer Research Center: Based on the Respondent’s acceptance of ORI’s research misconduct findings, ORI found that Dr. Sheng Wang, who has been an Assistant Professor, Department of Medicine, Boston University School of Medicine Cancer Research Center (BUSM), engaged in research misconduct in research supported by National Cancer Institute (NCI), National Institutes of Health (NIH), grants R01 CA102940 and R01 CA101992.

The two papers were: Read the rest of this entry »

Georgia (well, the Medical College there, anyway) on our minds for a mysterious retraction

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We’re watching a case which appears to involve more than meets the eye.

Molecular Endocrinology has retracted a 2010 study by researchers at the Medical College of Georgia. According to the Spartan retraction notice (we added a link): Read the rest of this entry »