Retraction Watch

Tracking retractions as a window into the scientific process

Archive for the ‘J Pharm Experimental Therapeutics’ Category

Shigeaki Kato up to 38 retractions

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Shigeaki Kato

Shigeaki Kato

Our retraction notice count for Shigeaki Kato, number seven on our leaderboard, has grown to 38.

The former University of Tokyo endocrinologist recently earned another retraction, for a paper in Archives of Biochemistry and Biophysics that contained image manipulation. As we’ve noted before, Kato resigned from the university in 2012 as it investigated his work for misconduct; in 2013 a Japanese newspaper reported that the investigation had found 43 papers from his lab contained “likely altered or forged materials.”

In addition to the new retraction, we’ve dug up four others for Kato from the past few years, plus one correction. Two of the retraction notices mention an investigation at the University of Tokyo.

First, the retraction note for “Multiple co-activator complexes support ligand-induced transactivation function of VDR,” published in December:

Read the rest of this entry »

U Colorado “golden boy” grad student faked data in drug lab, says investigation

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u coloradoA graduate student at the University of Colorado Denver faked data in his work at a drug research lab that has notched two retractions and an expression of concern over “data integrity,” according to an extensive university investigation.

It seems like many more retractions are on the horizon for grad student Rajendra Kadam, who worked in the lab of Uday Kompella, a pharmaceutical researcher at the university.  

Here’s an excerpt from the report, which you can read in full (but redacted) here: Read the rest of this entry »

JPET corrects Janssen antidepressant paper after neuroscience blogger notes errors

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Are drug company R&D departments reading blogs?

In a recent paper, “Translational evaluation of JNJ-18038683, a 5-HT7 receptor antagonist, on REM sleep and in major depressive disorder,” researchers with New Jersey-based Janssen Pharmaceuticals Inc. tested whether a potential drug code-named JNJ-18038683 that binds to a receptor linked to depression could actually help patients.

Turns out, the drug was a flop, but Read the rest of this entry »

Written by trevorlstokes

June 21st, 2012 at 9:58 am

JPET peeves: Paper withdrawn after drug company won’t disclose chemical structure

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A group of researchers at the drug company ChemoCentryx is withdrawing a 2012 paper in the Journal of Pharmacology and Experimental Therapeutics over failure to appropriately identify the molecule they describe in the article.

The withdrawal notice tells the story: Read the rest of this entry »

University of Perugia researcher faces trial for embezzlement, fraud following 13 retractions and Expressions of Concern

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Stefano Fiorucci, a gastroenterology researcher at the University of Perugia in Italy, has been indicted for fraud and embezzlement, after a university investigation found that he had manipulated images in papers that he used to win about 2 million Euros in grant funding.

The case, which has so far resulted in four retractions and nine Expressions of Concern, has dragged on for several years. The trial is scheduled for July. It’s the first time that embezzlement charges have been brought against a scientist found to have committed fraud, according to reports in Umbria 24 and the Umbria Journal.

Fiorucci’s attorney, Stefano Bagianti, told Umbria 24 that there was Read the rest of this entry »