Retraction Watch

Tracking retractions as a window into the scientific process

Archive for the ‘Cell Bio Internat’ Category

What turned a cancer researcher into a literature watchdog?

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Jennifer Byrne

Sometime in the middle of 2015, Jennifer Byrne, professor of molecular oncology at the University of Sydney, began her journey from cancer researcher to a scientific literature sleuth, seeking out potentially problematic papers.

The first step was when she noticed several papers that contained a mistake in a DNA construct which, she believed, meant the papers were not testing the gene in question, associated with multiple cancer types.  She started a writing campaign to the journal editors and researchers, with mixed success. But less than two years later, two of the five papers she flagged have already been retracted.

When asked why she spent time away from bench research to examine this issue, Byrne told us:  Read the rest of this entry »

Misidentified cell line fells cancer paper

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Screen Shot 2016-04-15 at 2.52.06 PMResearchers have retracted a paper about a new molecular target for cancer after realizing they had mistaken the identity of their cell line.

It’s all too easy to mix up cell lines, so we see plenty of retractions for that reason — and, according to an expert in the area, many more cases lurk uncorrected in the literature.

The retraction notice for “Knockdown of tumor protein D52-like 2 induces cell growth inhibition and apoptosis in oral squamous cell carcinoma” in Cell Biology International explains the authors’ perspective on this case:

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