The notices follow four retractions — two for image duplications and two for unknown reasons — for Anil K. Jaiswal. The three papers under notice are all on mechanisms that regulate gene expression; PubPeer commenters have raised questions about some of the figures in the papers.
The expression of concern on all three papers reads, in full:
The publisher of the Journal of Biological Chemistry is issuing this Expression of Concern to notify readers that questions have been raised with the corresponding author’s institution regarding some of the data and the conclusions in the articles listed above. This Expression of Concern is solely intended to notify readers for informational purposes. It is not a statement regarding the validity of the data. The Journal of Biological Chemistry will provide additional information as it becomes available.
The papers that bear this notice are:
- “Src subfamily kinases regulate nuclear export and degradation of transcription factor Nrf2 to switch off Nrf2-mediated antioxidant activation of cytoprotective gene expression,” cited 42 times, according to Thomson Scientific’s Web of Knowledge (PubPeer comments)
- “Prothymosin-alpha mediates nuclear import of the INrf2/Cul3Rbx1 complex to degrade nuclear Nrf2,” cited 46 times (PubPeer comments)
- “Phosphorylation and dephosphorylation of tyrosine 141 regulate stability and degradation of INrf2. A novel mechanism in Nrf2 activation,” cited 34 times (PubPeer comments)
The first author on two of those papers is Suryakant K. Niture, who shares three retractions with Jaiswal; we couldn’t find contact info for him. Abhinav K. Jain is the first author on one paper, and co-author on another.
all part of the same investigation. It’s been going on for at least two years, maybe longer.
We asked if he could provide details regarding which aspects of Jaiswal’s work were being investigated:
I can’t. That’s one of the restrictions I’m under.
We also reached out to Jaiswal and JBC. We’ll update this post with anything else we learn.
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