Data highjinx forces retraction of tumor paper in JBC
The Journal of Biological Chemistry has an illuminating retraction notice — we’re happy to be able to say — about a 2001 article from a group of researchers at the National University of Singapore.
The paper, “Intracellular acidification triggered by mitochondrial-derived hydrogen peroxide is an effector mechanism for drug-induced apoptosis in tumor cells,” was written by Jayshree L. Hirpara, Marie-Véronique Clément and Shazib Pervaiz.
It has has been cited 110 times, according to Thomson Scientific’s Web of Knowledge. According to the retraction notice:
Figs. 1 and 9C contain images that were taken from previous publications where they were described as representing the results of different experiments. Some of the data were labeled incorrectly, and permission for re-use of the data was not obtained from the copyright holder, although the articles in which the data in Figs. 1 and 9C were originally published were referenced in the text. Therefore, in accordance with accepted scientific practice, the authors have withdrawn the paper.
The paper had come to the attention of Abnormal Science back in 2011, when the blog reported that three articles by Pervaiz and Hirpara were under scrutiny for questionable findings. Pervaiz was a co-author on a paper that Nature Immunology retracted in 2011 — again for image issues — from a group led by Arilio Melendez, who once worked at the National University of Singapore.