Late last year, we reported on a retraction in Antioxidants & Redox Signaling (ARDS) by Indika Edirisinghe, who was at the University of Rochester when the original paper was published, and colleagues. On January 17, the Journal of Agricultural and Food Chemistry published a correction to “Effect of Black Currant Anthocyanins on the Activation of Endothelial Nitric Oxide Synthase (eNOS) in Vitro in Human Endothelial Cells,” on which Edirisinghe is also first author.
Western blots in Figure 5 were distorted in publication. Distortion is likely due to a problem with color/contrasting method that was used to remove background smears of the bands to help better visualize the data in print. The corrected figure gives the data derived from the same experiment without changing contrast/color. The graphs and the figure caption remain without any change. Overall, this correction will not affect the interpretation or conclusions of the manuscript.
Figure 5. Effect of vitamin C depleted black currant juice concentrates on the activation of Akt and eNOS in vitro in HUVECs. Vitamin C in the black currant sample (Ben Hope, BH) was eliminated using the method described under Materials and Methods. Representative immunoblots show the effect of BH and vitamin C depleted BH sample on phosphorylation of Akt (p-Akt) (A) and eNOS (p-eNOS) (B). Vitamin C (respective concentration found in BH sample) alone increased the level of p-Akt and p-eNOS significantly (P < 0.05). However, significant difference was not observed between BH samples and vitamin C depleted BH sample (P > 0.05). The histograms shown in both panels C and D are those obtained after quantification of the blots using densitometry (n = 3) for p-Akt and p-eNOS, respectively. The ordinates are the relative ratios of the phosphorylated and nonphosphorylated forms of each enzyme. () P < 0.05 and () P < 0.001, significant compared to control; (##) P < 0.01, significant compared to vitamin C (n = 3).
The paper has been cited six times, according to Thomson Scientific’s Web of Knowledge. We’ve contacted Edirisinghe to ask whether there would be any more corrections or retractions, and will update with anything we learn.
While we have you, Retraction Watch readers also uncovered a 2009 retraction of a Molecular Nutrition and Food Research paper and a 2008 correction in Respiratory Research by the senior author of the retracted ARDS paper, Irfan Rahman.